Protein Alignment Ir75d and Grin2d

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_036008580.1
• Gene: Grin2d / 14814
• MGIID: 95823
• Length: 1345
• Species: Mus musculus
• Alignment Length: 610
• Identity: 124/610 - (20%)
• Similarity: 206/610 - (33%)
• Gaps: 176/610 - (28%)

  Fly   113 APPPKSFHANNSTHWETSFLLPALPYKMGI---------------LLLEFSSECALNLLRWSAAS 162
            ||.|....|..|..|....   |.....|:               .|.|...:|..........|
Mouse   300 APLPAGLFAVRSAGWRDDL---ARRVAAGVAVVARGAQALLRDYGFLPELGHDCRAQNRTHRGES 361

  Fly   163 EHNYFTTNRFWLLLTEDPGDIDLLED-----PEIFIPPDSELRVLHYENVGNFSCSLIDLYKVAA 222
            .|.||      :.:|.|..|....||     |.:.:  .|..|...:|.||::....:.| |...
Mouse   362 LHRYF------MNITWDNRDYSFNEDGFLVNPSLVV--ISLTRDRTWEVVGSWEQQTLRL-KYPL 417

  Fly   223 WKPLKRTLVGHNIRNSRHVIHALQHFGSAITYRQDLEGIVFNSAIVI--AFPDLFTNIEDLSLRH 285
            |....|.|  ..:.:::|:..|            .||...|   :::  |.|...|.|.|    .
Mouse   418 WSRYGRFL--QPVDDTQHLTVA------------TLEERPF---VIVEPADPISGTCIRD----S 461

  Fly   286 IDTISKVN--HRL-------------------------MLELANRLNMSYNTYQTVN--YGWRQP 321
            :...|::|  |.|                         :..||:.:..||:.|...|  :| ::.
Mouse   462 VPCRSQLNRTHSLVAPRSPPPDAPRPEKRCCKGFCIDILKRLAHTIGFSYDLYLVTNGKHG-KKI 525

  Fly   322 NGSFDGLMGR--FQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIM---------------- 368
            :|.::|::|.  :||.::.:..|.|  ..:|..:|||..........:|
Mouse   526 DGVWNGMIGEVFYQRADMAIGSLTI--NEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLAF 588

  Fly   369 -FRQPPLSAVANIFAMPFENDVWVS--ILMLLIITTVVLVLELFFSPHNHDMSYM---------- 420
             :..||:|      ..|:...|||.  ::.|.::...|.:.| :.||..::.|..
Mouse   589 AWLMPPMS------PEPYSPAVWVMMFVMCLTVVAVTVFIFE-YLSPVGYNRSLATGKRPGGSTF 646

  Fly   421 ---DTLNFVWGAMCQQGFYVE-VRNRSARIIVFT-TFVAALFLFTSFSANIVALL--QSPSDAIQ 478
               .::..:|..:......|| .|..:::|:|.. .|.|.:|| .|::||:.|.:  :...|.:.
Mouse   647 TIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFL-ASYTANLAAFMIQEEYVDTVS 710

  Fly   479 SLSDLG-QSPLEIGVQDTQYNKIYF-TESTDPVTKNL------YHKKIASKGENIYMRPLLGMEK 535
            .|||.. |.|.|      ||..:.| |.......||:      .|..:....:......|..::.
Mouse   711 GLSDRKFQRPQE------QYPPLKFGTVPNGSTEKNIRSNYPDMHSYMVRYNQPRVEEALTQLKA 769

  Fly   536 MRTGLFAYQVELQAGYQIVSDTFSEPEKCGLMELEPFQLPMLAIPTRKNFP---YKELIRRQLRW 597
            .:...|.|...: ..|....|     |.|.|          :.|.:.|.|.   |...:.:..||
Mouse   770 GKLDAFIYDAAV-LNYMARKD-----EGCKL----------VTIGSGKVFATTGYGIALHKGSRW 818

  Fly   598 QREVSL----------VNREERKWI 612
            :|.:.|          :...||.|:
Mouse   819 KRPIDLALLQFLGDDEIEMLERLWL 843

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	49/223 (22%)
		Lig_chan	388..644	CDD:278489	56/265 (21%)
Grin2d	XP_036008580.1	Periplasmic_Binding_Protein_type1	<156..415	CDD:415822	27/126 (21%)
		PBP2_iGluR_NMDA_Nr2	432..849	CDD:270436	93/464 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830