Protein Alignment Ir75d and Grik2

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_011241422.1
• Gene: Grik2 / 14806
• MGIID: 95815
• Length: 943
• Species: Mus musculus
• Alignment Length: 818
• Identity: 162/818 - (19%)
• Similarity: 287/818 - (35%)
• Gaps: 254/818 - (31%)

  Fly    36 PDPKTRWGNQLPDMLVAYY--RHHGVHSLMLVVCHTDIADFRLWKLWQHFNLNNFY--------- 89
            |..:|||.:|:.|...::|  .:....||...:  .|:..|..||     .:...|
Mouse   128 PHIQTRWKHQVSDNKDSFYVSLYPDFSSLSRAI--LDLVQFFKWK-----TVTVVYDDSTGLIRL 185

  Fly    90 ---VQVSTESSLR-DLQHVDALDEHKDAPP-------PKSFHANNSTHWETSFLLPALPYKMGIL 143
               ::..:..:|| .::.:.|  :.|||.|       .|.||                      :
Mouse   186 QELIKAPSRYNLRLKIRQLPA--DTKDAKPLLKEMKRGKEFH----------------------V 226

  Fly   144 LLEFSSECALNLLRWSAAS------EHNYFTT------------------NRFWLLLTE------ 178
            :.:.|.|.|..:|:.:.|.      .|..|||                  ..|.:|.||
Mouse   227 IFDCSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDVEPYRYSGVNMTGFRILNTENTQVSS 291

  Fly   179 --DPGDIDLLEDPEIFIPPDSEL--------RVLHYE---------------NVGNFSCS----- 213
              :...::.|:.|.   .|||.|        ..|.|:               .|.:..|:
Mouse   292 IIEKWSMERLQAPP---KPDSGLLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSSLQCNRHKPW 353

  Fly   214 -----LIDLYKVAAWKPLKRTLVGHNIRNSR-----HVI----HALQHFG-----SAITYRQDLE 259
                 .:.|.|.|.|:.|...:..:.....|     .||    ..|:..|     |.:...:..:
Mouse   354 RFGTRFMSLIKEAHWEGLTGRITFNKTNGLRTDFDLDVISLKEEGLEKIGTWDPSSGLNMTESQK 418

  Fly   260 GIVFN--------SAIVIAF---PDLFTNIEDLSLRHIDTISKVNHRLMLELANRLNMSY--NTY 311
            |...|        |.||...   |.:.....|..|...|........|:.||:..|..:|  ...
Mouse   419 GKPANITDSLSNRSLIVTTILEEPYVLFKKSDKPLYGNDRFEGYCIDLLRELSTILGFTYEIRLV 483

  Fly   312 QTVNYGWRQP-NGSFDGLMGRFQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLS 375
            :...||.:.. ||.::|::.....::.|||...:.:...|..::||......:...|::|:|. .
Mouse   484 EDGKYGAQDDVNGQWNGMVRELIDHKADLAVAPLAITYVREKVIDFSKPFMTLGISILYRKPN-G 547

  Fly   376 AVANIFAM--PFENDVWVSILMLLIITTVVL---------------------------------- 404
            ....:|:.  |...|:|:.||:..:..:.||
Mouse   548 TNPGVFSFLNPLSPDIWMYILLAYLGVSCVLFVIARQSKFSWFKYPNCSHYHHSQRCLCTQHLES 612

  Fly   405 VLEL-------FFSPH--NHDMSYMDT----LNFVW---GAMCQQGFYVEVRNRSARIIVFTTFV 453
            .:||       :::||  |.|...::.    ||..|   ||:.|||..:..:..|.||:....:.
Mouse   613 YMELCLFSPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWF 677

  Fly   454 AALFLFTSFSANIVALL-----QSPSDAIQSLSDLGQSPLEIGVQDTQYNKIYFTESTDPVTKNL 513
            ..|.:.:|::||:.|.|     :||.|:...|:.  |:.:|.|..:......:|.:|    ..:.
Mouse   678 FTLIIISSYTANLAAFLTVERMESPIDSADDLAK--QTKIEYGAVEDGATMTFFKKS----KIST 736

  Fly   514 YHKK---IASKGENIYMRP-LLGMEKMRTGLFAYQVELQAGYQIVSDT--FSEPEKC------GL 566
            |.|.   ::|:.:::.::. ..|::::.|..:|:.:|        |.|  |.....|      ||
Mouse   737 YDKMWAFMSSRRQSVLVKSNEEGIQRVLTSDYAFLME--------STTIEFVTQRNCNLTQIGGL 793

  Fly   567 MELEPFQLPMLAIPTRKNFPYKELIR-RQLRWQREVSLVNREERKW----IPQKPKCEGGVGGFV 626
            ::.:.:     .:.|....||::.|. ..|:.|.|..|...:|:.|    .|::...|....|..
Mouse   794 IDSKGY-----GVGTPMGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEESKEASALGVQ 853

  Fly   627 SIGITECRYALGIF---GCGAAVSFVLFLFEFIFRHFK 661
            :||        |||   ..|..:|..:.:.||:::..|
Mouse   854 NIG--------GIFIVLAAGLVLSVFVAVGEFLYKSKK 883

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	53/243 (22%)
		Lig_chan	388..644	CDD:278489	69/330 (21%)
Grik2	XP_011241422.1	PBP1_iGluR_Kainate	37..414	CDD:380605	58/319 (18%)
		Periplasmic_Binding_Protein_Type_2	430..835	CDD:389745	88/424 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167846549
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840