Protein Alignment Ir75d and grik5

DIOPT Version :10

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_002936446.1
• Gene: grik5 / 100497490
• XenbaseID: XB-GENE-953974
• Length: 995
• Species: Xenopus tropicalis
• Alignment Length: 620
• Identity: 132/620 - (21%)
• Similarity: 235/620 - (37%)
• Gaps: 139/620 - (22%)

  Fly   119 FHANNSTH-------------WE-----TSFLLPALPYKM----------GILLLEFSSECALNL 155
            |...||:|             |.     :::|.|||...:          .:..|..|.|..:..
 Frog   271 FSMYNSSHPFYLEFLRSLNMSWRENCELSTYLGPALSAALMFDAVHVVVSAVRELNRSQEIGVKQ 335

  Fly   156 LRWSAASEHNYFTTNRFWLLLTEDPGDIDLLEDPEIFIPPDSELRVLHYENVGNFSCSLIDLYKV 220
            |..|.:....:.|:...:|.:.|..|....:|........:..||:|.....|:        .::
 Frog   336 LSCSTSQIWQHGTSLMNYLRMVEYDGLTGRVEFNSKGQRTNYTLRILEKAGDGH--------REI 392

  Fly   221 AAWKPLKRTLVGHNIRNSRHVIHALQHFGSAITYRQDLEGIVFNSAIVIAFPDLFTNIEDLSLRH 285
            ..|.. .|||             |:......::..:.||........::..|.:.......||..
 Frog   393 GVWYS-NRTL-------------AMNATSLDLSTSETLENKTLVVTTILENPYMMRKSNYRSLSG 443

  Fly   286 IDTISKVNHRLMLELANRLNMSYNTYQTVN--YGWRQPNGSFDGLMGRFQRYELDLAQLAIFMRL 348
            .|........:::|||..|..:|......:  ||..:||||:.|::|.....:.|||..|..:..
 Frog   444 NDQYEGFCAEMLMELAALLRFNYKIKLVEDGLYGAPEPNGSWTGMVGELINRKADLAVAAFTITA 508

  Fly   349 DRIALVDF--------VAETYRVRAGIMFRQPPLSAVANIFAMPFENDVWVSILMLLIITTVVLV 405
            :|..::||        ::..|||:.|   |:|...:    |..||...||:.:|:..:..:.||.
 Frog   509 EREKVIDFSKPFMTLGISILYRVQMG---RKPGYFS----FLDPFSPAVWLFMLLAYLAVSCVLF 566

  Fly   406 LEL------FFSPH------NHDMSYMDTL-NFVW---GAMCQQGFYVEVRNRSARIIVFTTFVA 454
            |..      :::||      :|.:....|| |.:|   |...|||..|..|..|.|.:....:..
 Frog   567 LAARLSPYEWYNPHPCLRERHHILENQYTLGNSLWFPVGGFMQQGSEVMPRALSTRCVSGVWWAF 631

  Fly   455 ALFLFTSFSANIVALL--QSPSDAIQSLSDLG-QSPLEIGVQDTQYNKIYFTESTDPVTKNLYHK 516
            .|.:.:|::||:.|.|  |.....|:|..||. |:.:|.|.........:|..|.....:.:::
 Frog   632 TLIIISSYTANLAAFLTVQRMEVPIESADDLADQTNIEYGTIHGGSTMTFFQNSRYQTYQRMWN- 695

  Fly   517 KIASKGENIYMRPL-LGMEKMRTGLFAYQVELQAGYQIVSDTFSEPEK---C------GLMELEP 571
            .:.||..:::::.. .|:.::....:|:.:|         .|.:|..:   |      ||::.:.
 Frog   696 YMNSKQPSVFVKSTEEGIARVLNSRYAFLLE---------STMNEYHRRLNCNLTQIGGLLDTKG 751

  Fly   572 FQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVNREERKWIPQKPKCEGGVG-----------GF 625
            :.:.|   |.  ..||::.|...:...:|.:.:...:|||      .|||..           |.
 Frog   752 YGIGM---PL--GSPYRDEITLAILQLQENNRLEILKRKW------WEGGKCPKEEDHRAKGLGM 805

  Fly   626 VSIGITECRYALGIFG---CGAAVSFVLFLFEFIF 657
            .:||        |||.   ||..::..:.:.||::
 Frog   806 ENIG--------GIFVVLICGLIIAVFVAIMEFVW 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>372	CDD:473866	25/82 (30%)
		Lig_chan	386..643	CDD:459656	65/299 (22%)
grik5	XP_002936446.1	PBP1_iGluR_Kainate_KA1_2	27..405	CDD:380616	28/155 (18%)
		Periplasmic_Binding_Protein_Type_2	418..788	CDD:473866	89/397 (22%)