Protein Alignment Ir75d and grin3b

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_017952374.2
• Gene: grin3b / 100497172
• XenbaseID: XB-GENE-990106
• Length: 1005
• Species: Xenopus tropicalis
• Alignment Length: 906
• Identity: 154/906 - (16%)
• Similarity: 276/906 - (30%)
• Gaps: 349/906 - (38%)

  Fly     2 KVQVAHWLPLIFFL-LVSGTPRVAGSWRSEYSRQDPDPKTRWGNQLPDMLVAYYRHHGVHSLM-- 63
            ::....|||....| :|||.||          .:.|...|||   |..:|||    .|:.:::
 Frog    59 RISRTSWLPYNLSLEVVSGAPR----------DRSPASLTRW---LCQVLVA----QGIAAVLAF 106

  Fly    64 -----------LVVCHTDIADFRLWKLWQHFNL---NNFYVQVSTESSLRDLQHVDALDEHKDAP 114
                       .:....:|....:.:..|...|   |.|::|:.|:||:.:|..:
 Frog   107 PQAQEELLQLEFLSSFLEIPFISILEQEQIVPLATKNPFHLQMDTQSSVENLMDI---------- 161

  Fly   115 PPKSFHANNSTHWETSFLLPALPYKMGILLLEFSSECALNLLRWSAASEHNYFTTNRFWLLLTED 179
               .|....::.||...::...|                    |.:||...|.|:|
 Frog   162 ---FFSVLQNSSWEEVDIITCHP--------------------WDSASIQRYLTSN--------- 194

  Fly   180 PGDIDLLEDPEIFIPPDSELRVL-----HYENVGN-------FSC-----SLIDLYKVAA----- 222
               ..|:....:.|.|..|..::     |:|::.|       :.|     ||:  ::||.
 Frog   195 ---TTLVSRTILNIHPVDESALVPFLQQHFESMKNPQFPMLLYGCDARRSSLV--FRVARDCGLE 254

  Fly   223 -----WKPLKRTLVGHNIRNSRHVIH----ALQHFGSAI-----TYRQDLEGIVFN--SAIVIAF 271
                 |      ::||.:........    .|..:|...     .:.:|..|:|..  ||.|...
 Frog   255 AHEFHW------MIGHPLNGEEMTTEGMPPGLLAYGEVSRPTMEKFIRDAVGLVTRAISAAVHVR 313

  Fly   272 PDL-----FTNIEDLSLRHIDTISKVNHRLM-----------LELANRL---------------N 305
            |||     ..|..|...:..::......|.:           :.::|.|               :
 Frog   314 PDLALIQSMVNCNDKQTKQNESSGSYLSRFLANTSFSGQTGQIYVSNNLIHTEHHYRIWSLVRDS 378

  Fly   306 MSYNTYQTVNYGWRQ-------------------------------------------------- 320
            :...|:.||. ||||
 Frog   379 LGDPTWVTVG-GWRQGKMEVEEGLWQSRIQQWEPAPGGFARTKLRVVTLVEHPFVFTREVDADGS 442

  Fly   321 ---------------------------PNGS-------------------------FD------- 326
                                       ||||                         ||
 Frog   443 CPAGQMCLDPRTNNSAVLDVLFEELNSPNGSVPLEYKTCCYGYCIDLLEKLSEDLRFDFELYIVG 507

  Fly   327 -------------GLMGRFQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLSAVA 378
                         ||:|........:|..:..:...|..::||.:..|....||:.|....::..
 Frog   508 DGKYGARKGDRWTGLVGDLLSGAAHMAVTSFSINSARSTVIDFTSPFYSTSLGILVRMRDTASPI 572

  Fly   379 NIFAMPFENDVWVSILMLLIITTVVLVLELFF--------SPHNHD----MSYMDTLNFVWGAMC 431
            ..|..|....:||.|.:.|.||.:.|.   |:        :||..:    .||...||..:..:
 Frog   573 GAFMWPLHWSMWVGIFVALHITALFLT---FYEWKSPFGMTPHGRNRTKIFSYSSALNLCYAIL- 633

  Fly   432 QQGFYVEVRNR-----SARIIVFTTFVAALFLFTSFSANIVALLQSPSDAIQSLSDLGQSPLEIG 491
               |...|.::     :.|:::....:..|.:.:|::||:.|::.. ....::||.:....|...
 Frog   634 ---FGRTVSSKTPKCCTGRVLMNLWAIFCLLVLSSYTANLAAVMVG-DKTFEALSGIHDPKLHHP 694

  Fly   492 VQDTQYNKIYFTESTDPVTKNL-----YHKK--IASKGENIYM----RPLLGMEKMRTGLFAYQV 545
            .|..::..::.:.:...:.|:.     |.:|  :.:..:.:::    .|.|....|...|..|:|
 Frog   695 SQGFRFGTVWESSAEQYIKKSFPEMHNYMRKFSVPATSDGVHLLKTDPPTLNAFIMDKALLDYEV 759

  Fly   546 ELQAGYQIVSDTFSEPEKCGLMEL-EPFQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVNREER 609
            .:.      ||       |.|:.: :||.:....|...:|.|....|...:...:....::....
 Frog   760 SID------SD-------CKLLTIGKPFAIEGYGIGLPQNSPLTSNISEFISRYKSSGFMDTLHD 811

  Fly   610 KWIPQKPKC-----------EGGVGGFVSIGITECRYALGIFGCGAAVSFVLFLFEFIFRH 659
            ||....| |           :.|:..|..:.:..|   :|.  ||   |.:..|.|.:..|
 Frog   812 KWYKMVP-CGKRVYAVTETLQMGIYHFSGLFVLLC---IGF--CG---SLLTSLMERVVYH 863

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	52/337 (15%)
		Lig_chan	388..644	CDD:278489	54/295 (18%)
grin3b	XP_017952374.2	PBP1_iGluR_NMDA_NR3	29..402	CDD:380600	76/413 (18%)
		PBP2_iGluR_NMDA_Nr3	418..814	CDD:270438	65/416 (16%)
		Lig_chan	582..848	CDD:395014	52/290 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910