Protein Alignment Ir75d and grik1

DIOPT Version :10

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_004912220.1
• Gene: grik1 / 100493949
• XenbaseID: XB-GENE-957124
• Length: 928
• Species: Xenopus tropicalis
• Alignment Length: 676
• Identity: 138/676 - (20%)
• Similarity: 257/676 - (38%)
• Gaps: 150/676 - (22%)

  Fly    54 YRHHGVHSLMLVVCHTDIADFRLWKLWQHFNLNNFYVQVSTES-SLRDLQHVDALDEHKDAPP-P 116
            ||:.||          ::..|||      .|::|..|....|. |:..||          ||| |
 Frog   278 YRYSGV----------NMTGFRL------LNIDNPQVSSVVEKWSMERLQ----------APPKP 316

  Fly   117 KS------------------FHANNSTHWETSFLLPAL------PYKMGILLLEFSSECALNLLR 157
            ::                  :....:|...|...:.:|      |::.|...:....|.     |
 Frog   317 ETGLLDGMMTTDAALMYDAVYMVAVATQRATQMTVSSLQCHRHKPWRFGPRFMSLIKEA-----R 376

  Fly   158 WSAASEHNYFTTNRFWLLLTEDPGDIDLLEDPEIFIPPDSELRVLHYENVGNFSCSLIDLYKVAA 222
            |...:  ...|.||...|..:  .|:|::...|..:...:...|.|...|..         ||..
 Frog   377 WDGLT--GRITFNRTDGLRRD--FDMDIISLKEDGMEKAAGETVNHLNKVWK---------KVGV 428

  Fly   223 WKPLKRTLVGHNIRN-SRHVIHALQHFGSAITYRQDLEGIVFNSAIVIAFPDLFTNIED--LSLR 284
            |.......:..|::: |.::..:|.                 |..:::.     |.:||  :..|
 Frog   429 WNSNTGLNMTDNLKDKSTNITDSLA-----------------NRTLIVT-----TILEDPYVMFR 471

  Fly   285 HIDTISKVNHR-------LMLELANRLNMSYNTYQTVN--YGWRQPNGSFDGLMGRFQRYELDLA 340
            ..|.....|.|       |:.||:|.|..:|.....|:  ||.:...|.::|::.....::.|||
 Frog   472 KSDKPLYGNDRFEGYCLDLLKELSNILGFTYEVRLVVDGKYGAQNDKGEWNGMVRELIDHKADLA 536

  Fly   341 QLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLSAVANIFAM--PFENDVWVSILMLLI-ITTV 402
            ...:.:...|..::||......:...|::|:|. .....:|:.  |...|:|:.:|:..: ::.|
 Frog   537 VAPLTITYVREKVIDFSKPFMTLGISILYRKPN-GTNPGVFSFLNPLSPDIWMYVLLACLGVSCV 600

  Fly   403 VLVLELF-----FSPH--NHDMSYMDT----LNFVW---GAMCQQGFYVEVRNRSARIIVFTTFV 453
            :.|:..|     ::||  |.|...::.    ||..|   ||:.|||..:..:..|.||:....:.
 Frog   601 LFVIARFTPYEWYNPHPCNPDSDVVENNFTLLNSFWFGVGALMQQGSELMPKALSTRIVGGIWWF 665

  Fly   454 AALFLFTSFSANIVALL-----QSPSDAIQSLSDLGQSPLEIGVQDTQYNKIYFTESTDPVTKNL 513
            ..|.:.:|::||:.|.|     :||.|:...|:.  |:.:|.|.........:|.:|.....:.:
 Frog   666 FTLIIISSYTANLAAFLTVERMESPIDSADDLAK--QTKIEYGAVRDGSTMTFFKKSKISTYEKM 728

  Fly   514 YHKKIASKGENIYMRPLLGMEKMRTGLFAYQVELQAGYQIVSDTFSEPEKCGLMELEPFQLPMLA 578
            :....:.:...:......|::::.|..:|..:|..:...:.....:..:..||::.:.:     .
 Frog   729 WAFMSSRQQTALVKNNDEGIQRVLTTDYALLMESTSIEYVTQRNCNLTQIGGLIDSKGY-----G 788

  Fly   579 IPTRKNFPYKELIR-RQLRWQREVSLVNREERKW----IPQKPKCEGGVGGFVSIGITECRYALG 638
            :.|....||::.|. ..|:.|.|..|...:|:.|    .|::...|....|..:||        |
 Frog   789 VGTPIGSPYRDKITIAILQLQEEGKLHMMKEKWWRGNGCPEEDSKEASALGVENIG--------G 845

  Fly   639 IF---GCGAAVSFVLFLFEFIFRHFK 661
            ||   ..|..:|..:.:.|||::..|
 Frog   846 IFIVLAAGLVLSVFVAIGEFIYKSRK 871

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>372	CDD:473866	18/74 (24%)
		Lig_chan	386..643	CDD:459656	60/284 (21%)
grik1	XP_004912220.1	PBP1_iGluR_Kainate	46..439	CDD:380605	39/204 (19%)
		Periplasmic_Binding_Protein_Type_2	454..823	CDD:473866	81/381 (21%)