Protein Alignment Ir75d and grid2

DIOPT Version :10

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_031759030.1
• Gene: grid2 / 100487676
• XenbaseID: XB-GENE-955038
• Length: 1007
• Species: Xenopus tropicalis
• Alignment Length: 652
• Identity: 127/652 - (19%)
• Similarity: 239/652 - (36%)
• Gaps: 182/652 - (27%)

  Fly    61 SLMLVVCHTDIADFRLWKLWQHFN--LNNFYVQVSTESSLRDLQHVDALDEHKDAPPP-----KS 118
            :|:...||           |...|  :|:..||.....|:..|..:     .:..|.|     :.
 Frog   250 NLVAFDCH-----------WIIINEEINDLDVQELVRRSIGRLTII-----RQTFPVPHNSSQRC 298

  Fly   119 FHANNSTHWETSFLLPALPYKMG-----------ILLLEFSSECALNLLRW-SAASEHNYFTTNR 171
            |..|:..  .||...|..|:...           :|||..:....|...:| |.||.......::
 Frog   299 FRGNHRI--STSLCDPKDPFSQNMEITNMYIYDTVLLLANAFHKKLEDRKWHSMASLTCIRKNSK 361

  Fly   172 FW-----LLLTEDPGDI-------DLLED---PEIFIPPDSELRVLHY-ENVGNFSCSLIDLYKV 220
            .|     :|.|...|.:       |..||   |.|:.    |:...:| |.:|.      .:.|:
 Frog   362 PWQGGRSMLETVKKGGVSGLTGALDFSEDGGNPNIYF----EILGTNYGEELGR------GIRKL 416

  Fly   221 AAWKP---LKRTLVGHNIRNSRHVIHALQHFGSAITYRQDLEGIVFNSAIVIAFPDLFTN----- 277
            ..|.|   |..:|....:.|                   ::.|:|...|.|:..|.:..:
 Frog   417 GFWNPVTGLNGSLTDRKLEN-------------------NMRGVVLRVATVLEEPFVMVSENVLG 462

  Fly   278 ----IEDLSLRHIDTISKVNHRLMLELANRLNMSYNTYQTVN--YGWRQPNGSFDGLMGRFQRYE 336
                .:..|:..:|.:|           :.|...|..|...:  ||..|.:||::||:|......
 Frog   463 KPKKYQGFSIDVLDALS-----------SYLGFKYEIYVASDHKYGSPQADGSWNGLIGELLLKR 516

  Fly   337 LDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLSAVANIFA--MPFENDVWVSILMLLII 399
            .|:...|:.:..||..:|||.........|::.|:  .....::||  .||:..:|..|...:::
 Frog   517 ADMGISALTITPDRENVVDFTTRYMDYSVGVLLRK--AEKTVDMFACLAPFDLSLWACIAGTVLL 579

  Fly   400 TTVVLVLELFFSPHNHDMSYM------DTLNFVWGAMCQQGFYVEVRNRSARIIVFTTFVAALFL 458
            ..:::.|..:.:|....|..|      :::.||:|:..|||..|.....:.|:::...::.||.:
 Frog   580 VGLLVYLLNWLNPPRLQMGSMTSTTLYNSMWFVYGSFVQQGGEVPYTTLATRMMMGAWWLFALIV 644

  Fly   459 FTSFSANIVALL--QSPSDAIQSLSDL-----------------------GQSPLEIGVQDTQYN 498
            .:|::||:.|.|  .....:||||.||                       |.:|.|   :|:.|:
 Frog   645 ISSYTANLAAFLTISRIESSIQSLQDLSRQTDIPYGTVFDSAVYEHVRVKGMNPFE---RDSMYS 706

  Fly   499 KIYFTESTDPVTKNLYHKKIASKGENIYMRPLLGMEKMRTGLFAYQVEL-----------QAGYQ 552
            :::          .:.::...|  ||.....|.|::|::.|.:|:..:.           ...:.
 Frog   707 QMW----------RMINRSNGS--ENNVQESLEGIQKVKHGNYAFVWDAAVLEYIAINDQDCSFY 759

  Fly   553 IVSDTFSEPEKCGLMELEPFQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVNREERKWIPQKPK 617
            .|.:|.::..              ..|..:...||:::..:::...::...::..:.||.|:..:
 Frog   760 TVGNTIADRG--------------YGIALQHGSPYRDIFSQRILELQQNGDMDILKHKWWPRNGQ 810

  Fly   618 CE 619
            ||
 Frog   811 CE 812

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>372	CDD:473866	20/74 (27%)
		Lig_chan	386..643	CDD:459656	50/276 (18%)
grid2	XP_031759030.1	Periplasmic_Binding_Protein_type1	28..429	CDD:471960	43/206 (21%)
		PBP2_iGluR_delta_2	440..806	CDD:270449	79/407 (19%)