Protein Alignment Ir75d and grin3bb

DIOPT Version :10

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_017213803.2
• Gene: grin3bb / 100333101
• ZFINID: ZDB-GENE-131122-77
• Length: 1114
• Species: Danio rerio
• Alignment Length: 775
• Identity: 143/775 - (18%)
• Similarity: 253/775 - (32%)
• Gaps: 215/775 - (27%)

  Fly    46 LPDMLVAYYRHHGVHSLMLVVCH--TDIADFRLWKLWQHFNL--NNFYVQVS---TESSLRDLQH 103
            |.::|:|..:..|....|.|:||  .|.....|.||...|..  :.::::.:   :.|:.|....
Zfish   170 LVELLLAVLQRSGWEESMAVLCHGWEDAGLLDLLKLQGRFGWGPSQWHLRAALNLSHSTARMANI 234

  Fly   104 VDALDEH--KDAPPPKS---FHAN--------NSTHWETSFLLPALPYKMGILL----------- 144
            .|.|.||  .|..||.|   |.|:        .|.| :....||.:.:.||..|
Zfish   235 SDFLSEHFNLDHSPPASVLLFGADPECASSVLRSAH-DLGLTLPTVHWIMGHPLSPDALHSIGLP 298

  Fly   145 -------------LEFSSECALNLLR----------------------WSAASEHNYFTTNRF-- 172
                         |:|....||.|:.                      :...::|...::.::
Zfish   299 LGLLAYGEVDHKPLDFYISDALQLINRAVTAATVVRPDLALIQNMVNCFDKPNKHELPSSGQYIA 363

  Fly   173 -WLLLTEDPGDIDLLEDPEIFIPPDSELRVLH----------------YENVGNFSCSLIDLYKV 220
             :|..|...|    |..|.|.....|.:...|                :..||::....:::.:.
Zfish   364 RFLSNTSFVG----LTGPVIVQRNLSRVHTSHKVHIWSLRRDAVGQPTWVTVGSWEGGRLNVEEQ 424

  Fly   221 AAWK---PLKRT-----------LVGHNIRNSRHVIHALQHFGSAITYRQDLEGIVFNSAIVIAF 271
            ..|:   |.:||           ..|..:..||..:..|.......|...|.:|   |.......
Zfish   425 GLWQGSSPRQRTEGQMGREGRRWRAGFPVSGSRLRVVTLVEHPFVFTREVDEDG---NCPAGQYC 486

  Fly   272 PDLFTNIEDLSLRHI-------------DTISKVNHRLMLELANRL----NMSYNTYQTVN--YG 317
            .|..||..: :|.|:             ...||..:...::|..:|    |..::.|...:  ||
Zfish   487 LDAGTNSSE-TLDHLYAERAQGNKSFLPPDYSKCCYGYCIDLLEKLSEDMNFEFDLYIVGDGKYG 550

  Fly   318 WRQPNGSFDGLMGRFQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLSAVANIFA 382
             ....|.:.||:|.......|:|..:..:...|..::||.:..:....||:.|....:|....|.
Zfish   551 -AVKGGQWTGLVGDLLSGVADMAVTSFSINSARSKVIDFTSPFFSTSLGILVRSKDTAAPIGAFM 614

  Fly   383 MPFENDVWVSILMLLIITTVVLVL-----ELFFSPHNHD----MSYMDTLNFVWGAMCQQGFYVE 438
            .|....:|:.|.:.|.||.:.|.|     ....:||..:    .||...||..:..:    |...
Zfish   615 WPLHWSMWMGIFVALHITALFLTLYEWKSPFGMTPHGRNRVKVFSYSSALNLCYAIL----FGRT 675

  Fly   439 VRNR-----SARIIVFTTFVAALFLFTSFSANIVALLQSPSDAIQSLSDLGQSPLEIGVQDTQYN 498
            |.::     :.|.::....:..|.:.:|::||:.|::.. ....:.:|.:..:.|....|..::.
Zfish   676 VSSKTPKCWTGRFLMNLWAIFCLLVLSSYTANLAAVMVG-EKTFEEVSGIHDAKLHHPSQGFRFG 739

  Fly   499 KIYFTESTDPVTKNL--YHKKIASKGENIYMR------------------PLLGMEKMRTGLFAY 543
            .:..:.:.|.:.|:.  .|:         |||                  |.|....|...|..|
Zfish   740 TVRESSAEDYMKKSFPEMHE---------YMRKFNEPTTPDGVATLKTDPPQLDAFIMDKALLDY 795

  Fly   544 QVELQAGYQIVSDTFSEPEKCGLMEL-EPFQLPMLAIPTRKNFPYKELIRRQLRWQREVSLVNRE 607
            :|.:.|             .|.|:.: :||.:....|...:|.|....|...:...:....::..
Zfish   796 EVSIDA-------------DCKLLTVGKPFAIEGYGIGLPQNSPLTSNISEFVSRYKSDGYMDML 847

  Fly   608 ERKWIPQKPKCEGGVGGFVSIGITECRYALGIFGCGAAVSFVLFLFEFIFRHFKQVYRII 667
            ..||....|                         ||..|..|....:...|||..::.::
Zfish   848 HDKWYKVVP-------------------------CGKRVFAVTETLQMGIRHFSGLFVLL 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>372	CDD:473866	18/78 (23%)
		Lig_chan	386..643	CDD:459656	48/291 (16%)
grin3bb	XP_017213803.2	Periplasmic_Binding_Protein_type1	39..427	CDD:471960	48/261 (18%)
		PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	80/426 (19%)
		Lig_chan	618..885	CDD:459656	55/317 (17%)