Protein Alignment Ir75d and gria4

DIOPT Version :10

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: XP_031751480.1
• Gene: gria4 / 100125052
• XenbaseID: XB-GENE-5838893
• Length: 902
• Species: Xenopus tropicalis
• Alignment Length: 692
• Identity: 139/692 - (20%)
• Similarity: 260/692 - (37%)
• Gaps: 144/692 - (20%)

  Fly    86 NNFYVQVSTESSLRDLQHVDALDEHKDAPPPKSFHANNSTHWETSFLLPALPYK----------- 139
            |.|.:....|.....|:.:.::.:|     .|.:|          :::..|.:|
 Frog   207 NKFVIDCEVERLQNILEQIVSVGKH-----VKGYH----------YIIANLGFKDISLDRFMHGG 256

  Fly   140 ---MGILLLEFSSECALNLL-RWSAASEHNY---FTTNRFWLLLTEDPGDIDLLEDPEIFIPPDS 197
               .|..|::|::.....|: ||....:..|   .:..::...||.|    .:|...|.|
 Frog   257 ANVTGFQLVDFNTPIVTELMQRWKTLDQREYPGSESPPKYTSALTYD----GVLVMAEAF----- 312

  Fly   198 ELRVLHYENV-----GNFSCSLIDLYKVAAWK---PLKRTLVGHNIRNSRHVIHALQHFGSAITY 254
              |:|..:.:     ||....|.:  ..|.|.   .::|||....|:.....|. ..|:|..:.|
 Frog   313 --RILRRQKIDLSRRGNAGDCLAN--PAAPWGQGIDMERTLKQVRIQGLTGNIQ-FDHYGRRVNY 372

  Fly   255 RQDLEGIVFNSAIVI----------------AFPDLFTNIEDLSLRHIDTI-------SKVNHRL 296
            ..|:..:..|....|                ||.:..:.||:.:: .:.||       .|.||.|
 Frog   373 TMDVLELKSNGLRKIGYWNDMDKLVLLQHEPAFKNDSSGIENRTV-IVTTILEAPYVMYKKNHEL 436

  Fly   297 M--------------LELANRLNMSYN--TYQTVNYGWRQPNGS-FDGLMGRFQRYELDLAQLAI 344
            :              .|:|..:.:.|.  ......||.|..... ::|::|.....:.::|...:
 Frog   437 LEGNDKFEGYCVDLAYEIAKHIGIKYKIAIVPDGKYGARDSETKIWNGMVGELVYGKAEIAVAPL 501

  Fly   345 FMRLDRIALVDFVAETYRVRAGIMFRQPPLSAVANIFAM--PFENDVWVSILMLLIITTVVLVLE 407
            .:.|.|..::||......:...||.::|..|. ..:|:.  |...::|:.|:...|..:|||.|.
 Frog   502 TITLVREEVIDFSKPFMSLGISIMIKKPQKSK-PGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLV 565

  Fly   408 LFFSPHN------------------HDMSYMDTLNFVWGAMCQQGFYVEVRNRSARIIVFTTFVA 454
            ..|||:.                  ::....::|.|..||..|||..:..|:.|.||:....:..
 Frog   566 SRFSPYEWHTEEPEDGKEGPSDQPPNEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFF 630

  Fly   455 ALFLFTSFSANIVALLQ-----SPSDAIQSLSDLG-QSPLEIGVQDTQYNKIYFTESTDPVTKNL 513
            .|.:.:|::||:.|.|.     ||   |:|..||. |:.:..|..|....|.:|..|...|.:.:
 Frog   631 TLIIISSYTANLAAFLTVERMVSP---IESAEDLAKQTEIAYGTLDAGSTKEFFKRSKIAVYEKM 692

  Fly   514 YHKKIASKGENIYMRPLL-GMEKMR--TGLFAYQVELQAGYQIVSDTFSEPEKCGLMEL-EPFQL 574
            : ..:.|...:::.:... |:.::|  .|.||:.:|     ..:::...:.:.|..|:: .....
 Frog   693 W-TYMKSAEPSVFTKTTAEGVARVRKSKGKFAFLLE-----STMNEYIEQRKPCDTMKVGGNLDS 751

  Fly   575 PMLAIPTRKNFPYKELIRRQLRWQREVSLVNREERKWIPQKPKCEGGVGGFVSIGITECRYALGI 639
            ....:.|.|:...:..:...:....|..|:::.:.||...|.:|  |.||..|...|.......:
 Frog   752 KGYGVATPKHSQLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGEC--GSGGGDSKDKTSALSLSNV 814

  Fly   640 FGC------GAAVSFVLFLFEFIFRHFKQVYRIIKGYREVQR 675
            .|.      |..::.::.|.||.::...:..|:...:.|..|
 Frog   815 AGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKLTFSEAIR 856

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>372	CDD:473866	15/75 (20%)
		Lig_chan	386..643	CDD:459656	63/290 (22%)
gria4	XP_031751480.1	PBP1_iGluR_AMPA_GluR4	28..400	CDD:380611	40/221 (18%)
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	81/391 (21%)