Protein Alignment Ir75d and grin2ca

DIOPT Version :9

• Sequence 1: NP_649074.2
• Gene: Ir75d / 40065
• FlyBaseID: FBgn0036829
• Length: 675
• Species: Drosophila melanogaster
• Sequence 2: NP_001352716.1
• Gene: grin2ca / 100003342
• ZFINID: ZDB-GENE-070822-3
• Length: 1400
• Species: Danio rerio
• Alignment Length: 630
• Identity: 123/630 - (19%)
• Similarity: 232/630 - (36%)
• Gaps: 159/630 - (25%)

  Fly   132 LLPALPYKMGILLLEFSSECALNLLRWSAASEHNYFTTNRFWLLLTEDPGDIDLLEDPEIFIPPD 196
            |.|..|...|.|....     || :.|    |:..|:.|          .|..|:....|.|..|
Zfish   329 LSPIRPASNGTLYRHM-----LN-VSW----ENTDFSFN----------SDGYLVNPSMIIITLD 373

  Fly   197 SELRVLHYENVGNFSCSLIDLYKVAAWKPLKRTLVGHNIRNSRHV-IHALQHFGSAITYRQD-LE 259
               |...::.|||:...::.: :...| |...|.: ..:.::||: :..|:.....|....| :.
Zfish   374 ---RGRQWDKVGNYESGILQM-RYPVW-PRYGTFL-EPVSDNRHLTVATLEERPFVIVEAVDPVT 432

  Fly   260 GIVFNSAIVIAFPDLFTNIEDLSLRHIDTISKVNHR-----LMLELANRLNMSYNTYQTVN--YG 317
            |...::.:.....   :|..:..:.|.:..:|:..:     ::.:|:..:..||:.|...|  :|
Zfish   433 GTCLSNTVPCRRQ---SNKTETIVGHTEPYTKLCCKGFCIDILKKLSRNIKFSYDLYLVTNGKHG 494

  Fly   318 WRQPNGSFDGLMGRFQRYELDLAQLAIFMRLDRIALVDFVAETYRVRAGIMFRQPPLSAVANIFA 382
             :...|.::|::|.......|:|..::.:..:|..::||..........:|..:...:...:.|.
Zfish   495 -KLVRGIWNGMIGEVFYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTVSPSAFL 558

  Fly   383 MPFENDVWVS--ILMLLIITTVVLVLELFFSPHNHDMSYMDTLN-------------FVWGAMCQ 432
            .|:...|||.  ::.|.::...|.|.| :.||..::.|.:...:             .:||.:..
Zfish   559 EPYSPAVWVMMFVMCLTVVAVTVFVFE-YCSPVGYNRSLVSAKDPGGPTFTIGKSVWLLWGIVFN 622

  Fly   433 QGFYVE-VRNRSARIIVFT-TFVAALFLFTSFSANIVALL--QSPSDAIQSLSDLG-QSPLEIGV 492
            ....:| .:..:::|:|.. .|.|.:|| .|::||:.|.:  :...|.:..|||.. |.|
Zfish   623 NSVPIENPKGTTSKIMVLVWAFFAVIFL-ASYTANLAAFMIQEQYIDTVSGLSDKKFQKP----- 681

  Fly   493 QDTQYNKIYF----TESTDPVTKNLYHK------KIASKG-ENIYMRPLLGMEKMRTG---LFAY 543
            || ||....|    ..||:...::.|.:      |...|| |:       .:..::||   .|.|
Zfish   682 QD-QYPPFRFGTVPNGSTERNIRSNYPEMHSHMVKYNQKGVED-------ALNSLKTGKLDAFIY 738

  Fly   544 QVELQAGYQIVSDTFSEPEKCGLMELEPFQLPMLAIPTRKNFP---YKELIRRQLRWQREVSL-- 603
            ...: ..|....|     |.|.|          :.|.:.|.|.   |...::::.||:|.:.|
Zfish   739 DAAV-LNYMAGKD-----EGCKL----------VTIGSGKVFATTGYGIALQKESRWKRPIDLAL 787

  Fly   604 -------------------VNREERKWI-PQKPKCEGGVGGFVSIGITECRYALGIFGCGAAVSF 648
                               :.|.|:|.: ..|...:...|.|..:.:     |:|:       |.
Zfish   788 LQFLADGDTQKLQTVWLTGICRNEKKEVMSSKLDIDNMAGVFYMLLV-----AMGL-------SL 840

  Fly   649 VLFLFEFI----FRH--------------FKQVYRIIKGYREVQR 675
            ::|.:|.:    .||              .:.:|....|..:..|
Zfish   841 LVFAWEHLLYWKLRHSVRKSERLDFLLAISRGIYSCFNGVEDTDR 885

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir75d	NP_649074.2	Periplasmic_Binding_Protein_Type_2	299..>483	CDD:304360	43/204 (21%)
		Lig_chan	388..644	CDD:278489	66/314 (21%)
grin2ca	NP_001352716.1	PBP1_iGluR_NMDA_NR2	38..398	CDD:107373	21/93 (23%)
		PBP2_iGluR_NMDA_Nr2	409..810	CDD:270436	84/435 (19%)
		NMDAR2_C	847..>938	CDD:313729	5/39 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591558
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830