DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CSN1b and FUS6

DIOPT Version :9

Sequence 1:	NP_524152.2	Gene:	CSN1b / 40063	FlyBaseID:	FBgn0027057	Length:	525	Species:	Drosophila melanogaster
Sequence 2:	NP_567109.1	Gene:	FUS6 / 825286	AraportID:	AT3G61140	Length:	441	Species:	Arabidopsis thaliana

Alignment Length:	491	Identity:	192/491 - (39%)
Similarity:	287/491 - (58%)	Gaps:	62/491 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 QNAVEPMQVDIAPPNEDNENNEEQQIVVENPSIDLEVYANQYAGIVRLHRLIYVADVC---PVLA 72
            :.|..||........|:..|   ::.::....:|:|.||..|.|..::.||:::|:.|   ..|.
plant     5 EEASGPMMEMCTNGGEETSN---RRPIISGEPLDIEAYAALYKGRTKIMRLLFIANHCGGNHALQ 66

  Fly    73 VEALKMAITYVQTTYNVNLYQVLHKRLSDLNAGNAPAPPANAGGDQAGAAAPGPLAAAPLPDIAA 137
            .:||:||...::...|..|::.:                .|..|::.|
plant    67 FDALRMAYDEIKKGENTQLFREV----------------VNKIGNRLG----------------- 98

  Fly   138 QPVAQAQGQAQPAVEKDAFAYDAAWVDTKMKKAALKLEKLDSDLKNYKSNSIKESIRRGHDDLAD 202
                            :.:..|.||.:...::|..|..||:::|.:|::|.||||||.|::|..|
plant    99 ----------------EKYGMDLAWCEAVDRRAEQKKVKLENELSSYRTNLIKESIRMGYNDFGD 147

  Fly   203 HYLSCGDLTNALKCYSRARDYCTSGKHVVNMCLNVIKVSIYLQNWAHVMSYISKAESTPDFAEGS 267
            .|.:||.|.:|.|.|.|.|||||:.||:::||:|.|.|||.:..:.||.||::|||..|:..|
plant   148 FYYACGMLGDAFKNYIRTRDYCTTTKHIIHMCMNAILVSIEMGQFTHVTSYVNKAEQNPETLE-- 210

  Fly   268 KEANAQVHTRLECAAGLAELQQKKYKVAAKHFLNANFD-HCDFPEMISTSNVAVYGGLCALATFD 331
                ..|:.:|.||:|||.|:.||||:||:.||:.|.: ...:.|:|:..::|.||||||||:||
plant   211 ----PMVNAKLRCASGLAHLELKKYKLAARKFLDVNPELGNSYNEVIAPQDIATYGGLCALASFD 271

  Fly   332 RQELKRLVIASTSFKLFLELEPQLRDIIFKFYESKYASCLTLLDEIRDNLLVDMYIAPHVTTLYT 396
            |.|||:.||.:.:|:.||||.|.:|::|..||.|:|||||..|..::.|||:|:::..||.|||.
plant   272 RSELKQKVIDNINFRNFLELVPDVRELINDFYSSRYASCLEYLASLKSNLLLDIHLHDHVDTLYD 336

  Fly   397 KIRNRALIQYFSPYMSADMHKMAMAFNSSVGDLENEVMQLILDGQIQARIDSHNKILFAKEADQR 461
            :||.:|||||..|::|.|:.:||.||.:||..||.|:..||.|.|||||||||||||:|:.||||
plant   337 QIRKKALIQYTLPFVSVDLSRMADAFKTSVSGLEKELEALITDNQIQARIDSHNKILYARHADQR 401

  Fly   462 NSTFERALIMGKQYQRHTRMLVLRAAMLKSHIHVKS 497
            |:||::.|.||.::.|..|.::|||.:||...|.:|
plant   402 NATFQKVLQMGNEFDRDVRAMLLRANLLKHEYHARS 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN1b	NP_524152.2	RPN7	159..338	CDD:287560	84/179 (47%)
CSN1b	NP_524152.2	PCI	353..457	CDD:279707	57/103 (55%)
FUS6	NP_567109.1	RPN7	104..278	CDD:402301	84/179 (47%)
FUS6	NP_567109.1	PCI	293..397	CDD:396121	57/103 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	169	1.000	Domainoid score	I1171
eggNOG	1	0.900	-	-		E1_KOG0686
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3046
Inparanoid	1	1.050	345	1.000	Inparanoid score	I632
OMA	1	1.010	-	-		QHG55412
OrthoDB	1	1.010	-	-		D859626at2759
OrthoFinder	1	1.000	-	-		FOG0005242
OrthoInspector	1	1.000	-	-		oto4015
orthoMCL	1	0.900	-	-		OOG6_103258
Panther	1	1.100	-	-	LDO	PTHR14145
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5623
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840