Protein Alignment CG6843 and cir-1

DIOPT Version :9

• Sequence 1: NP_649072.1
• Gene: CG6843 / 40062
• FlyBaseID: FBgn0036827
• Length: 366
• Species: Drosophila melanogaster
• Sequence 2: NP_491654.1
• Gene: cir-1 / 172225
• WormBaseID: WBGene00018892
• Length: 560
• Species: Caenorhabditis elegans
• Alignment Length: 410
• Identity: 160/410 - (39%)
• Similarity: 219/410 - (53%)
• Gaps: 71/410 - (17%)

  Fly     1 MGKGFNNYMCKKFFHPASRDNLKRVWMAEQQAEAYKKKQEELRNQYEKEQNLHENKAMLSKDSKD 65
            |||||.|:|.||.|||::..|||.||.|.|:.....|:|||||..|||||.:..|||:|. |.|.
 Worm     1 MGKGFQNFMSKKDFHPSAFRNLKMVWEARQKKSLEDKRQEELRVAYEKEQEILNNKALLG-DEKA 64

  Fly    66 KLSVNFMYEPPPGVRKEREKDDNEPEYKFEWQRKYNAPRESYCKGDTEIRDQPFGIQVRNVRCLK 130
            |:.::|||:.|.|:.| ||:...||  ||||||||.||||.:.||:.||:|||||||||||||.|
 Worm    65 KMGLSFMYDAPAGMTK-REEPKEEP--KFEWQRKYQAPREDWAKGNEEIQDQPFGIQVRNVRCCK 126

  Fly   131 CHKWGHINTDKECTMYSIS---------------MSEARKLHAETEASDIMAKN----------- 169
            ||||||||||:||.::..|               :.:.|:...|.:|....:|:
 Worm   127 CHKWGHINTDRECPLFGKSGNFEDEGYANNPSDLIKDLRRRRQEGKAGPSTSKSSAAAATGEDDD 191

  Fly   170 ---------VLEEQMKEDGLMMKRSAQELQSIRAIQQQHQLVPSDGEKDAHADDQNPELVFLKSL 225
                     :..:..:|.|:.:|.|.     :..:|...||.....|    ..::...|.|..|:
 Worm   192 EDEWMDHQQLASDMREEHGIKLKSSV-----LAGMQTDQQLTRMKKE----MTEEEMMLEFFNSM 247

  Fly   226 SKKQKLKLLKKLEKIERMKRKGEGIKKPTKRKSKKERHEKDSKKKKSKKDKSSRKDKKGSVSNSS 290
            ::|:|.||.|||       ..|..::...|:|||||: :|:.|:|:..|||...| ||...|.|.
 Worm   248 TEKEKKKLHKKL-------MSGADLEDVMKKKSKKEK-KKEKKEKRKNKDKKKDK-KKNKKSKSR 303

  Fly   291 DSSSSSDSSDSEDNHKSNHRDDKRNGHQRTRDSDHSYQRR--------SNENRH-RRDRSRSRDR 346
            ::...||.|||||:.|  .:..||  .:|..:|...|:.:        .:||.| |:|.||.|..
 Worm   304 ETDDDSDGSDSEDDWK--EKSSKR--IKREVESSPEYRSKYIKQEVLSEDENSHGRKDSSRKRAH 364

  Fly   347 SRSLSRDRRRERERRDRSRR 366
            :.|.|.:..|..||: ||||
 Worm   365 NDSESSNEVRSSERK-RSRR 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6843	NP_649072.1	Cir_N	13..49	CDD:287204	18/35 (51%)
cir-1	NP_491654.1	Cir_N	13..49	CDD:198151	18/35 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158208
Domainoid	1	1.000	180	1.000	Domainoid score	I2102
eggNOG	1	0.900	-	-		E1_KOG3794
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	237	1.000	Inparanoid score	I2136
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58189
OrthoDB	1	1.010	-	-		D1604301at2759
OrthoFinder	1	1.000	-	-		FOG0006267
OrthoInspector	1	1.000	-	-		oto18754
orthoMCL	1	0.900	-	-		OOG6_106007
Panther	1	1.100	-	-	LDO	PTHR13151
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3109
SonicParanoid	1	1.000	-	-		X5216
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	14	13.840