DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and ydiO

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_416210.4	Gene:	ydiO / 945626	ECOCYCID:	G6918	Length:	383	Species:	Escherichia coli

Alignment Length:	385	Identity:	111/385 - (28%)
Similarity:	193/385 - (50%)	Gaps:	18/385 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 LTDDEKMMKETVAKLAQEQI-QPLVKKMDFEHKFDPSVVKAVFENGLMGIEIDTELGGSGCNFMT 100
            ||::::::..::.:|..... :...:..|....:....::|:.:||:..:.:..|.||...:::|
E. coli     5 LTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMRALADNGISMLGVPEEFGGIPADYVT 69

  Fly   101 NIVVVEELSKIDPAVAAFVDIHNTLVNSLMIKFGNAEQKAKYLPKLAQ------EYAGSFALTEP 159
            .::.:.|:||.  ...||:..:...::| |.:||:|||    |.|.|:      :.|.:.|||||
E. coli    70 QMLALMEVSKC--GAPAFLITNGQCIHS-MRRFGSAEQ----LRKTAESTLETGDPAYALALTEP 127

  Fly   160 GAGSDAFSLKTV-AKKDGSHYVINGSKMWISNSDVAGVFLIFA-NAKPEDGYRGITTFIVDRETP 222
            |||||..|..|. .:|:|..| |||.|.:|:.:......|:.| :.:|:|..:..|.:.||...|
E. coli   128 GAGSDNNSATTTYTRKNGKVY-INGQKTFITGAKEYPYMLVLARDPQPKDPKKAFTLWWVDSSKP 191

  Fly   223 GLIVNKPEDKLGIRASGTCQLTFDNVRVPEENILGTFGHGYKYAAGFLNEGRIGIAAQMVGLAQG 287
            |:.:| |..|:|.....||::..|||.|.|.:::|..|.|:..........|:..||:..|.|:.
E. coli   192 GIKIN-PLHKIGWHMLSTCEVYLDNVEVEESDMVGEEGMGFLNVMYNFEMERLINAARSTGFAEC 255

  Fly   288 TFDATIPYLLERKQFGDAIYNFQSMQHQIATVATEIEAARLMTYNAARLQEQGVPFQKEAAMAKY 352
            .|:....|..:|..||..|.:.|.:|.::|.:|.:|:..|.|....|...:|....:..||:||.
E. coli   256 AFEDAARYANQRIAFGKPIGHNQMIQEKLALMAIKIDNMRNMVLKVAWQADQHQSLRTSAALAKL 320

  Fly   353 YASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIGAIYEGTTNMQLSTIAKCIKKDY 412
            |.:..|.......:..|||:|:|.:....:::|||:...|..||..:.:....:.|.|||
E. coli   321 YCARTAMEVIDDAIQIMGGLGYTDEARVSRFWRDVRCERIGGGTDEIMIYVAGRQILKDY 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	111/385 (29%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	106/379 (28%)
ydiO	NP_416210.4	PRK12341	1..381	CDD:183454	111/385 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	97	1.000	Domainoid score	I372
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	183	1.000	Inparanoid score	I179
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000508
OrthoInspector	1	1.000	-	-		mtm9754
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
	7	6.860