DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and ACAD10

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_001130010.1	Gene:	ACAD10 / 80724	HGNCID:	21597	Length:	1090	Species:	Homo sapiens

Alignment Length:	442	Identity:	112/442 - (25%)
Similarity:	190/442 - (42%)	Gaps:	63/442 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SLKKLPVRMLANAARQQSAAMSSATGLPPPLTFLTDDEKMMKETVAKLAQEQIQ----------- 57
            |...:|....|:.:|  ...:.|...|.||:..|....|...|.....|:.::|
Human   666 SYSSVPEASPAHTSR--GGLVISPESLSPPVRELYHRLKHFMEQRVYPAEPELQSHQASAARWSP 728

  Fly    58 -PLVKKMDFEHKFDPSVVKAVFENGLMGIEIDTELG-GSG---------CNFM-TNIVVVEELSK 110
             ||::  |.:.|.....:..:|    :.:|.|.|.. |:|         |..| |::...|..:.
Human   729 SPLIE--DLKEKAKAEGLWNLF----LPLEADPEKKYGAGLTNVEYAHLCELMGTSLYAPEVCNC 787

  Fly   111 IDPAVAAFVDIHNTLVNSLMIKFGNAEQKAKYL-PKLAQEYAGSFALTEPG-AGSDAFSLKTVAK 173
            ..|      |..|.   .|::::|...|||::| |.|..:....||:|||. |.|||.:::...:
Human   788 SAP------DTGNM---ELLVRYGTEAQKARWLIPLLEGKARSCFAMTEPQVASSDATNIEASIR 843

  Fly   174 KDGSHYVINGSKMWISNSDVAGVF-------LIFANAKPE-DGYRGITTFIVDRETPGLIVNKPE 230
            ::.|.|||||.|.||:     |:.       :......|. ..:|..:..:|..:|||:.:.:|.
Human   844 EEDSFYVINGHKWWIT-----GILDPRCQLCVFMGKTDPHAPRHRQQSVLLVPMDTPGIKIIRPL 903

  Fly   231 DKLGIR--ASGTCQLTFDNVRVPEENILGTFGHGYKYAAGFLNEGRIGIAAQMVGLAQGTFDATI 293
            ...|:.  ..|..::.|::||||:||::...|.|::.|.|.|..|||....:::|.::.......
Human   904 TVYGLEDAPGGHGEVRFEHVRVPKENMVLGPGRGFEIAQGRLGPGRIHHCMRLIGFSERALALMK 968

  Fly   294 PYLLERKQFGDAIYNFQSMQHQIATVATEIEAARLMTYNAARLQEQGVPFQKEA----AMAKYYA 354
            ..:..|..||..:....::...||....|||.|||:...||.|.:  :...|.|    ||.|..|
Human   969 ARVKSRLAFGKPLVEQGTVLADIAQSRVEIEQARLLVLRAAHLMD--LAGNKAAALDIAMIKMVA 1031

  Fly   355 SEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIGAIYEGTTNMQLSTIAK 406
            ..:|.|...:.:...|..|.:.|:|..:::...:.....:|...:..:|:||
Human  1032 PSMASRVIDRAIQAFGAAGLSSDYPLAQFFTWARALRFADGPDEVHRATVAK 1083

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	104/409 (25%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	103/407 (25%)
ACAD10	NP_001130010.1	HAD-1A3-hyp	41..278	CDD:274054
		HAD_like	46..238	CDD:304363
		PLN02876	288..1087	CDD:215473	112/442 (25%)
		ACAD10_11_N-like	317..567	CDD:270703
		ACAD	694..1087	CDD:299127	104/412 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910