DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and Acadsb

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_080102.1	Gene:	Acadsb / 66885	MGIID:	1914135	Length:	432	Species:	Mus musculus

Alignment Length:	406	Identity:	235/406 - (57%)
Similarity:	308/406 - (75%)	Gaps:	0/406 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KLPVRMLANAARQQSAAMSSATGLPPPLTFLTDDEKMMKETVAKLAQEQIQPLVKKMDFEHKFDP 71
            |:|.|:|.::..:...::::......||..|||:|.|||:||.|.|||.:.|||..||...|.:.
Mouse    27 KIPPRVLKSSQPEALVSLTNNAVAFAPLQTLTDEEIMMKQTVKKFAQEHVAPLVSSMDENSKMEK 91

  Fly    72 SVVKAVFENGLMGIEIDTELGGSGCNFMTNIVVVEELSKIDPAVAAFVDIHNTLVNSLMIKFGNA 136
            ||::.:|:.||||||::.:.||:..:|..:::|:|||:|:|.:||...||.||::|:|..|..:.
Mouse    92 SVIQGLFQQGLMGIEVEAQYGGTEASFFCSVLVIEELAKVDASVALLCDIQNTIINNLFRKHASE 156

  Fly   137 EQKAKYLPKLAQEYAGSFALTEPGAGSDAFSLKTVAKKDGSHYVINGSKMWISNSDVAGVFLIFA 201
            ||||.|||||..|..|||.|:|.|||||:|::||.|.|.|::||:||||||||:::.|.:||:||
Mouse   157 EQKATYLPKLVTEKLGSFCLSEAGAGSDSFAMKTRADKSGNYYVLNGSKMWISHAEHAELFLVFA 221

  Fly   202 NAKPEDGYRGITTFIVDRETPGLIVNKPEDKLGIRASGTCQLTFDNVRVPEENILGTFGHGYKYA 266
            |..|..||||||.|:|||:|.|..:.|.|:|:|||||.||||||:||:|||.||||..|||||||
Mouse   222 NVDPSSGYRGITCFLVDRDTEGFQIGKRENKMGIRASSTCQLTFENVKVPETNILGKIGHGYKYA 286

  Fly   267 AGFLNEGRIGIAAQMVGLAQGTFDATIPYLLERKQFGDAIYNFQSMQHQIATVATEIEAARLMTY 331
            .|.||||||||||||:|||||.||.||||:.||.|||..|::||.:|||:|.|||::||.||:||
Mouse   287 IGSLNEGRIGIAAQMLGLAQGCFDYTIPYIKERMQFGKRIFDFQGLQHQVAQVATQLEATRLLTY 351

  Fly   332 NAARLQEQGVPFQKEAAMAKYYASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIGAIYEGT 396
            |||||.|.|.||.|||:||||||||||.....||::||||||:|:|:|.||::||.|||.||||.
Mouse   352 NAARLVEAGRPFIKEASMAKYYASEVAGLTTSKCIEWMGGVGYTKDYPVEKFFRDAKIGTIYEGA 416

  Fly   397 TNMQLSTIAKCIKKDY 412
            :|:||:||||.|..:|
Mouse   417 SNIQLNTIAKHIDAEY 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	229/376 (61%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	226/370 (61%)
Acadsb	NP_080102.1	CaiA	57..428	CDD:224871	227/370 (61%)
		SCAD_SBCAD	59..430	CDD:173847	226/370 (61%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:P45954	291..294		2/2 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839444
Domainoid	1	1.000	219	1.000	Domainoid score	I2636
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1216
Inparanoid	1	1.050	488	1.000	Inparanoid score	I1408
Isobase	1	0.950	-	0	Normalized mean entropy	S1951
OMA	1	1.010	-	-		QHG53594
OrthoDB	1	1.010	-	-		D589058at2759
OrthoFinder	1	1.000	-	-		FOG0000508
OrthoInspector	1	1.000	-	-		oto94724
orthoMCL	1	0.900	-	-		OOG6_102170
Panther	1	1.100	-	-	LDO	PTHR43884
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3530
SonicParanoid	1	1.000	-	-		X2781
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750