DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and acox1

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_001015762.1	Gene:	acox1 / 548479	XenbaseID:	XB-GENE-1008078	Length:	661	Species:	Xenopus tropicalis

Alignment Length:	479	Identity:	104/479 - (21%)
Similarity:	180/479 - (37%)	Gaps:	114/479 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 MLANAARQQSAAMSSATGLPPPLTFLTD--DEKMMKETVAKLAQEQIQPLV-KKMDFEHKFDPSV 73
            |..:.:|:::||..:    |..:|.:.|  .|:..:       :.:|:.|| ....|:|: ||:.
Frog     1 MNPDLSRERAAASFN----PETITVILDGSPERTRR-------RREIEGLVLNDPSFQHE-DPNF 53

  Fly    74 VK-------AVFENGLMGIEIDTELGGSGCNFMTNIVVVEELSKIDPA----VAAFV-------- 119
            :.       |:.::.||                  :..:.|....||.    ..:||
Frog    54 LSRSERYELAIKKSALM------------------VQKMREHGISDPEEIYWFKSFVHRGRPEPL 100

  Fly   120 DIHNTLVNSLMIKFGNAEQKAK-YLPKLAQEYAGSFALTEPGAGSDAFSLKTVAKKDGS--HYVI 181
            |:|..:....::.....||:.: ::|....|..|::|.||.|.|:....|:|.|..|.|  .:::
Frog   101 DLHLGMFLPTLLNQATPEQQERLFMPAWNLEIIGTYAQTEMGHGTHLRGLETTATYDPSTQEFIL 165

  Fly   182 NGS-----KMW------ISNSDVAGVFLIFANAKPEDGYRGITTFIV-------DRETPGLIVNK 228
            |..     |.|      .||..|     :.|....:...||:..|||       ....||::|..
Frog   166 NSPTVSSIKWWPGGLGKTSNHAV-----VLAQLYTQGECRGLHAFIVPIRHMGTHEPLPGVVVGD 225

  Fly   229 PEDKLGIRASGTCQLTFDNVRVPEENIL---------GTFGH--GYKYAAG---FLNEGRIGIAA 279
            ...|.|...:....|.||.:|:|.||:|         ||:..  ..|...|   |:....:|.:|
Frog   226 IGPKFGFDETDNGFLKFDKLRIPRENMLMKYAKVEPDGTYVKPLSDKLTYGTMVFIRSMIVGDSA 290

  Fly   280 QMVGLAQGTFDATIPYLLERKQ----FGD---AIYNFQSMQHQIATVATEIEAARLM------TY 331
            :.:..|   ....|.|...|.|    .|:   .|.:||:.|:::..:.....|.:.:      ||
Frog   291 RSLSRA---CTIAIRYSAVRHQSEIRAGEPEPQILDFQTQQYKLFPLLATAYAFQFVGSYMSHTY 352

  Fly   332 N--AARLQEQGVPFQKE----AAMAKYYASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIG 390
            :  :|.:|...:....|    :|..|.:.:..|.....:|....||.|::|.......|......
Frog   353 HRISAEIQAGNLNELPELHALSAGLKAFTTWAANTGIEECRMACGGHGYSRCSGIPDIYVTFTPA 417

  Fly   391 AIYEGTTNMQLSTIAKCIKKDYAA 414
            ..|||...:.:...|:.:.|.|.|
Frog   418 CTYEGENTVMMLQTARFLVKSYKA 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	97/452 (21%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	95/446 (21%)
acox1	NP_001015762.1	AXO	3..638	CDD:173839	103/477 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910