DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and Acox1

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_059036.1	Gene:	Acox1 / 50681	RGDID:	619757	Length:	661	Species:	Rattus norvegicus

Alignment Length:	459	Identity:	101/459 - (22%)
Similarity:	162/459 - (35%)	Gaps:	100/459 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 SSATGLPPPLTFLTDDEKMMKETVAKLAQEQIQPLV-KKMDFEH----------------KFDPS 72
            :|||..|..:|.:.|..   .|...:  :.:|:.|: ...||:|                |...:
  Rat    10 ASATFNPELITHILDGS---PENTRR--RREIENLILNDPDFQHEDYNFLTRSQRYEVAVKKSAT 69

  Fly    73 VVKAVFENGLMGIEIDTELGGSGCNFMTNIVVVEELSKIDPAVAAFVDIHNTLVNSLMIKFGNAE 137
            :||.:.|.|:...|   |:......::.|.|        :|....:.....||:|.     |...
  Rat    70 MVKKMREYGISDPE---EIMWFKKLYLANFV--------EPVGLNYSMFIPTLLNQ-----GTTA 118

  Fly   138 QKAKYL-PKLAQEYAGSFALTEPGAGSDAFSLKTVAKKD--GSHYVINGS-----KMW------I 188
            |:.|:: |....:..|::|.||.|.|:....|:|.|..|  ...:::|..     |.|      .
  Rat   119 QQEKWMRPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKT 183

  Fly   189 SNSDVAGVFLIFANAKPEDGYRGITTFIV-------DRETPGLIVNKPEDKLGIRASGTCQLTFD 246
            ||..:     :.|....:....|:..|:|       .:..||:.|.....|.|........|..|
  Rat   184 SNHAI-----VLAQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMD 243

  Fly   247 NVRVPEENIL---------GTFGH--GYKYAAG---FLNEGRIGIAAQMVGLAQGTFDATIPYLL 297
            |.|:|.||:|         ||:..  ..|...|   |:....:|.|||.:..|   ....|.|..
  Rat   244 NYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKA---CTIAIRYSA 305

  Fly   298 ERKQF-------GDAIYNFQSMQHQ----IATVATEIEAARLMTYNAARLQE---QG----VP-F 343
            .|:|.       ...|.:||:.|::    :||........|.|.....|:.|   ||    :| .
  Rat   306 VRRQSEIKQSEPEPQILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPEL 370

  Fly   344 QKEAAMAKYYASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIGAIYEGTTNMQLSTIAKCI 408
            ....|..|.:.:..|.....:|....||.|::........|........:||...:.:...|:.:
  Rat   371 HALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFL 435

  Fly   409 KKDY 412
            .|.|
  Rat   436 MKIY 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	96/447 (21%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	94/441 (21%)
Acox1	NP_059036.1	AXO	3..638	CDD:173839	101/459 (22%)
Acox1	NP_059036.1	Microbody targeting signal	659..661
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810