DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and Acox57D-p

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_001286677.1	Gene:	Acox57D-p / 37445	FlyBaseID:	FBgn0034628	Length:	677	Species:	Drosophila melanogaster

Alignment Length:	512	Identity:	90/512 - (17%)
Similarity:	166/512 - (32%)	Gaps:	149/512 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MMNSLKKLPVRMLANAARQQSAAMSSATGLPPPLTFLTDDEKMMK--ETVAKLAQEQIQPLVKKM 63
            |.:|...:|..:..:..:::.||..::...   ..:....|:::|  ..|.:..::.:. |.:.:
  Fly     1 MASSTSVIPTTVNPDLQKERDAASFNSEEF---AAWWAGGEEVLKFNRGVREYMEKDVD-LSEML 61

  Fly    64 DFEHKFDPSVVKAVFENGLMGIE----IDTELGGSGCNFMTNIVVVEELSKIDPAVAAFVDIHNT 124
            ..::|....:::......:.|.:    :..|....|..:..|:...:.:..:.|....|..::..
  Fly    62 QLQNKTHEEIIEFSTRGAIEGAKKLRRLQEERNPGGDVYWPNLYDAQVMWGLVPGGNPFGVMYVM 126

  Fly   125 LVNSLMIKFGNAEQKAKYLPKLAQEY---------AGSFALTEPGAGSDAFSLKTVAKKD--GSH 178
            ||.:|         :|:..|:..:|:         .|::|.||.|.|:....|:|.|..|  ...
  Fly   127 LVKAL---------QAQCTPEQYEEFGKRVELFEICGTYAQTELGHGTYLRGLETRADFDRKTDQ 182

  Fly   179 YVIN-----GSKMW------ISN-----------SDVAGVFLIFANAKPEDGYRGITTFIVDRET 221
            :|:|     ..|.|      .||           .|..|..:.|...:.||.:..:
  Fly   183 FVLNTPNISSYKWWPGGLGHSSNHCLVMAQLYIDGDCKGPHMFFIQVRDEDTHEPL--------- 238

  Fly   222 PGLIVNKPEDKLGIRASGTCQLTFDNVRVPEENILGTFGHGYKYAAGFLNEGRIGIAAQMVGLAQ 286
            ||:.:.....|:|........|...|||:|...:|  ..|                 ||:  .|.
  Fly   239 PGVHIGDIGKKMGFIGVNNGFLGLKNVRIPRTRML--MRH-----------------AQV--KAD 282

  Fly   287 GTFDAT----IPYLLERKQFGDAIYNFQSMQHQIATVATEIEAARLMTYNAARLQEQGVPFQKEA 347
            |::.::    :.|....:.......|...|....||:||.        |:|.|.|....|.::|.
  Fly   283 GSYVSSPTNVLTYFAMVRTRCVIAKNNAVMLASAATIATR--------YSAVRRQSPINPNEREP 339

  Fly   348 AMAKY----------YASEVAQRAA----------------------------------IKC--- 365
            .:..:          .|:.||.|.|                                  :.|
  Fly   340 QIMDHVTQQMKLFPEIATSVAYRKAGDYLWNLYDVTIEDIENGKYERLPELHSLSCALKVTCSMD 404

  Fly   366 ----VDWM----GGVGFTRDFPQEKYYRDVKIGAIYEGTTNMQLSTIAKCIKKDYAA 414
                |:.:    ||.||.........|........|||...:.|..|.:.:.|.:.|
  Fly   405 SASGVEKLRLACGGHGFLTSSNMSSIYVSATAACTYEGENTVLLLQIGRFLMKTWRA 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	84/474 (18%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	83/468 (18%)
Acox57D-p	NP_001286677.1	ACAD	14..653	CDD:299127	87/499 (17%)
Acox57D-p	NP_001286677.1	PLN02443	16..677	CDD:178062	87/497 (18%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45460761
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740