DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and ACADS

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_000008.1	Gene:	ACADS / 35	HGNCID:	90	Length:	412	Species:	Homo sapiens

Alignment Length:	403	Identity:	147/403 - (36%)
Similarity:	240/403 - (59%)	Gaps:	8/403 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RMLANAARQQSAAMSSATGLPPPLTFLTDDEKMMKETVAKLAQEQIQPLVKKMDFEHKFDPSVVK 75
            |.|...|.:|...:..:..||       :..:|:.:|....|::::.|:..::|.||.|..:.||
Human    15 RALCPRAWRQLHTIYQSVELP-------ETHQMLLQTCRDFAEKELFPIAAQVDKEHLFPAAQVK 72

  Fly    76 AVFENGLMGIEIDTELGGSGCNFMTNIVVVEELSKIDPAVAAFVDIHNTLVNSLMIKFGNAEQKA 140
            .:...||:.:::..||||:|.:::...:.:||:|:...:....:.::|:|....::|||:.|||.
Human    73 KMGGLGLLAMDVPEELGGAGLDYLAYAIAMEEISRGCASTGVIMSVNNSLYLGPILKFGSKEQKQ 137

  Fly   141 KYL-PKLAQEYAGSFALTEPGAGSDAFSLKTVAKKDGSHYVINGSKMWISNSDVAGVFLIFANAK 204
            .:: |..:.:..|.|||:|||.||||.:..|.|:.:|..:|:||:|.||:|:..|...::||:..
Human   138 AWVTPFTSGDKIGCFALSEPGNGSDAGAASTTARAEGDSWVLNGTKAWITNAWEASAAVVFASTD 202

  Fly   205 PEDGYRGITTFIVDRETPGLIVNKPEDKLGIRASGTCQLTFDNVRVPEENILGTFGHGYKYAAGF 269
            .....:||:.|:|...||||.:.|.|||||||.|.|..|.|::.|:|:::|||..|.|:|.|...
Human   203 RALQNKGISAFLVPMPTPGLTLGKKEDKLGIRGSSTANLIFEDCRIPKDSILGEPGMGFKIAMQT 267

  Fly   270 LNEGRIGIAAQMVGLAQGTFDATIPYLLERKQFGDAIYNFQSMQHQIATVATEIEAARLMTYNAA 334
            |:.||||||:|.:|:||...|..:.|...|..||..:...|.:|.::|.:|..:|:|||:|:.||
Human   268 LDMGRIGIASQALGIAQTALDCAVNYAENRMAFGAPLTKLQVIQFKLADMALALESARLLTWRAA 332

  Fly   335 RLQEQGVPFQKEAAMAKYYASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIGAIYEGTTNM 399
            .|::...||.|||||||..|||.|...:.:.:..:||:|:..:.|.|::|||.:|..|||||:.:
Human   333 MLKDNKKPFIKEAAMAKLAASEAATAISHQAIQILGGMGYVTEMPAERHYRDARITEIYEGTSEI 397

  Fly   400 QLSTIAKCIKKDY 412
            |...||..:.:.|
Human   398 QRLVIAGHLLRSY 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	141/377 (37%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	140/371 (38%)
ACADS	NP_000008.1	CaiA	33..412	CDD:224871	143/385 (37%)
ACADS	NP_000008.1	SCAD_SBCAD	36..408	CDD:173847	140/371 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D589058at2759
OrthoFinder	1	1.000	-	-		FOG0000508
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820