DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and Acad11

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_001101651.1	Gene:	Acad11 / 315973	RGDID:	1306270	Length:	779	Species:	Rattus norvegicus

Alignment Length:	426	Identity:	110/426 - (25%)
Similarity:	189/426 - (44%)	Gaps:	46/426 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RMLANAARQQSAAMSSATGLPPPLTFLTDDEKMMKETVAKLAQEQIQPLVKKMDFEHKFD-PSVV 74
            |:.|.:.|.|..              ||..::.||:.|....:|..:...:..:...|:: |.|:
  Rat   370 RLFAQSRRGQEV--------------LTRVKQFMKQHVFPAEKEVAEYYAQNGNSAEKWEHPLVI 420

  Fly    75 KAVFE----NGLMGIEIDTELGGSGCNFMTNIVVVEELSKIDPAVAAF----VDIHNTLVNSLMI 131
            :.:.|    .||..:.:...   ||.:.:...::.||..|...|...|    .|..|..|..|
  Rat   421 EKLKEMAKAEGLWNLFLPAV---SGLSQVDYALIAEETGKCFFAPDVFNCQAPDTGNMEVLHL-- 480

  Fly   132 KFGNAEQKAKYL-PKLAQEYAGSFALTEPG-AGSDAFSLKTVAKKDGSHYVINGSKMWISNSDVA 194
             :|:.:||.::| |.|..:....|.:|||. :.|||.:::...::||..|:::|.|.|.|.   |
  Rat   481 -YGSEQQKQQWLEPLLRGDITSVFCMTEPNVSSSDATNMECSIQRDGGSYIVHGKKWWSSG---A 541

  Fly   195 G-------VFLIFANAKPEDGYRGITTFIVDRETPGLIVNKPEDKLGIRAS---GTCQLTFDNVR 249
            |       |.|....:.....::..:..:|..:|||:.:.:|....|...:   |..::.|::||
  Rat   542 GNPKCKIAVVLGRTESPSVSRHKVHSMILVPMDTPGVELIRPLSVFGYMDNVHGGHWEVHFNHVR 606

  Fly   250 VPEENILGTFGHGYKYAAGFLNEGRIGIAAQMVGLAQGTFDATIPYLLERKQFGDAIYNFQSMQH 314
            ||..|::...|.|::.:.|.|..|||....:.||||:..........::|:.||..:|..:.:.|
  Rat   607 VPASNLILGEGRGFEISQGRLGPGRIHHCMRSVGLAERILQIMCDRAVQREAFGKKLYEHEVVAH 671

  Fly   315 QIATVATEIEAARLMTYNAARLQEQ--GVPFQKEAAMAKYYASEVAQRAAIKCVDWMGGVGFTRD 377
            .||.....||..||:|..||...:.  ....:||.||.|..|.:...:.|.:.:...||.|.::|
  Rat   672 WIAKSRIAIEEIRLLTLKAAHSIDTLGSAAARKEIAMIKVAAPKAVCKIADRAIQVHGGAGVSQD 736

  Fly   378 FPQEKYYRDVKIGAIYEGTTNMQLSTIAKCIKKDYA 413
            :|....|..::...:.:|...:.||.|||...:|.|
  Rat   737 YPLANMYAIIRTLRLADGPDEVHLSAIAKMELQDQA 772

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	106/400 (27%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	102/393 (26%)
Acad11	NP_001101651.1	PLN02876	10..769	CDD:215473	108/421 (26%)
		ACAD10_11_N-like	42..295	CDD:270703
		ACAD_FadE2	376..769	CDD:173844	106/415 (26%)
		Substrate binding. /evidence=ECO:0000250	628..631		0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910