DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and Acadsb

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	XP_008758088.1	Gene:	Acadsb / 25618	RGDID:	2013	Length:	449	Species:	Rattus norvegicus

Alignment Length:	393	Identity:	226/393 - (57%)
Similarity:	293/393 - (74%)	Gaps:	10/393 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KLPVRMLANAARQQSAAMSSATGLP---PPLTFLTDDEKMMKETVAKLAQEQIQPLVKKMDFEHK 68
            |:|.|:|.::   |..|:.|.|...   .||...||::.||::.|.|.|||||.|||..||...|
  Rat    27 KIPPRVLKSS---QPEALLSVTNNALCFAPLQTFTDEDIMMQKAVKKFAQEQIAPLVSTMDENSK 88

  Fly    69 FDPSVVKAVFENGLMGIEIDTELGGSGCNFMTNIVVVEELSKIDPAVAAFVDIHNTLVNSLMIKF 133
            .:.||::.:|:.|:||||::.:.||:..:|:.:::|:|||:|:|.:||...||.||::|.|..|.
  Rat    89 MEKSVIQGLFQQGMMGIEVEAKYGGTEASFLCSVLVIEELAKVDASVALLCDIQNTVINKLFRKH 153

  Fly   134 GNAEQKAKYLPKLAQEYAGSFALTEPGAGSDAFSLKTVAKKDGSHYVINGSKMWISNSDVAGVFL 198
            |..||||.|||||..|..|||.|:|.|||||:|:|||.|.|.|::||||||||||||::.|.:||
  Rat   154 GTEEQKATYLPKLVTEKLGSFCLSEAGAGSDSFALKTRADKSGNYYVINGSKMWISNAEHAELFL 218

  Fly   199 IFANAKPEDGYRGITTFIVDRETPGLIVNKPEDKLGIRASGTCQLTFDNVRVPEENILGTFGHGY 263
            :|||..|..||||||.|:|||:|.|..:.:.|:|:|||||.||||||:||:|||.::||..||||
  Rat   219 VFANVDPPSGYRGITCFLVDRDTEGFQIGRRENKMGIRASSTCQLTFENVKVPETSVLGKIGHGY 283

  Fly   264 KYAAGFLNEGRIGIAAQMVGLAQGTFDATIPYLLERKQFGDAIYNFQSMQHQIATVATEIEAARL 328
            |||.|.||||||||||||:|||||.||.||||:.||.|||..|::||.:|||:|.|||::|||||
  Rat   284 KYAIGSLNEGRIGIAAQMLGLAQGCFDYTIPYIKERMQFGKRIFDFQGLQHQVAHVATQLEAARL 348

  Fly   329 MTYNAARLQEQGVPFQKEAAMAKYYASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIGAIY 393
            :|||||||.|.|.||.|||:||||||||||.....||::||||||:|:|:|.||::||.||
  Rat   349 LTYNAARLVEAGRPFIKEASMAKYYASEVAGLTTSKCIEWMGGVGYTKDYPVEKFFRDAKI---- 409

  Fly   394 EGT 396
            ||:
  Rat   410 EGS 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	216/360 (60%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	215/358 (60%)
Acadsb	XP_008758088.1	CaiA	57..409	CDD:224871	212/351 (60%)
Acadsb	XP_008758088.1	SCAD_SBCAD	59..409	CDD:173847	211/349 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343261
Domainoid	1	1.000	222	1.000	Domainoid score	I2510
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1216
Inparanoid	1	1.050	485	1.000	Inparanoid score	I1392
OMA	1	1.010	-	-		QHG53594
OrthoDB	1	1.010	-	-		D331445at33208
OrthoFinder	1	1.000	-	-		FOG0000508
OrthoInspector	1	1.000	-	-		oto98229
orthoMCL	1	0.900	-	-		OOG6_102170
Panther	1	1.100	-	-	LDO	PTHR43884
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2781
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	16	15.770