DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and Acadvl

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_037023.1	Gene:	Acadvl / 25363	RGDID:	2014	Length:	655	Species:	Rattus norvegicus

Alignment Length:	427	Identity:	140/427 - (32%)
Similarity:	221/427 - (51%)	Gaps:	26/427 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SLKKLPVRMLANAARQQSAAMSSATG-------LPPPLTFLTDDEKMMKETVAKLAQ--EQIQPL 59
            |.::.|.|     |..:|.|:....|       .|.|........:.:||.|..:|:  |::...
  Rat    60 STREKPAR-----AESKSFAVGMFKGQLTTDQVFPYPSVLNEGQTQFLKELVGPVARFFEEVNDP 119

  Fly    60 VKKMDFEHKFDPSVVKAVFENGLMGIEIDTELGGSGCNFMTNIVVVEELSKIDPAVAAFVDIHNT 124
            .|....| |.:...::.:.|.|..|:::.:||||.|.:......:.|.:...|..|:..:..|.:
  Rat   120 AKNDSLE-KVEEDTLQGLKELGAFGLQVPSELGGLGLSNTQYARLAEIVGMHDLGVSVTLGAHQS 183

  Fly   125 LVNSLMIKFGNAEQKAKYLPKLAQEYA-GSFALTEPGAGSDAFSLKT--VAKKDGSHYVINGSKM 186
            :....::.:|...||.||||::|...| .:|.||||.:|||..|:::  |....|.:|.:||||:
  Rat   184 IGFKGILLYGTKAQKEKYLPRVASGQALAAFCLTEPSSGSDVASIRSSAVPSPCGKYYTLNGSKI 248

  Fly   187 WISNSDVAGVFLIFANAKPEDGYRG-----ITTFIVDRETPGLIVNKPEDKLGIRASGTCQLTFD 246
            ||||..:|.:|.:||....:|...|     ||.|:|:|...|:....||.|:||:||.|.::.||
  Rat   249 WISNGGLADIFTVFAKTPIKDAATGAVKEKITAFVVERSFGGVTHGLPEKKMGIKASNTSEVYFD 313

  Fly   247 NVRVPEENILGTFGHGYKYAAGFLNEGRIGIAAQMVGLAQGTFDATIPYLLERKQFGDAIYNFQS 311
            .|:||.||:||..|.|:|.|...||.||.|:||.:.|..:......:.:...|.||||.|:||..
  Rat   314 GVKVPAENVLGEVGDGFKVAVNILNNGRFGMAATLAGTMKAIIAKAVDHATNRTQFGDKIHNFGV 378

  Fly   312 MQHQIATVATEIEAARLMTYNAARLQEQGV-PFQKEAAMAKYYASEVAQRAAIKCVDWMGGVGFT 375
            :|.::|.:|........|.|..:...:||. .||.|||::|.:.||.|.:...:|:..|||:||.
  Rat   379 IQEKLARMAILQYVTESMAYMLSANMDQGFKDFQIEAAISKIFGSEAAWKVTDECIQIMGGMGFM 443

  Fly   376 RDFPQEKYYRDVKIGAIYEGTTNMQLSTIA--KCIKK 410
            ::...|:..||::|..|:|||.::....:|  .|:.|
  Rat   444 KEPGVERVLRDIRIFRIFEGTNDILRLFVALQGCMDK 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	131/387 (34%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	130/383 (34%)
Acadvl	NP_037023.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..70		4/14 (29%)
		Catalytic. /evidence=ECO:0000250\|UniProtKB:P49748	41..482		140/427 (33%)
		VLCAD	72..481	CDD:173850	136/410 (33%)
		CaiA	100..473	CDD:224871	128/373 (34%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:P49748	461..463		0/1 (0%)
		Membrane-anchoring. /evidence=ECO:0000250\|UniProtKB:P49748	483..516
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810