DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and F54D5.7

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_001369890.1	Gene:	F54D5.7 / 174768	WormBaseID:	WBGene00010052	Length:	409	Species:	Caenorhabditis elegans

Alignment Length:	412	Identity:	125/412 - (30%)
Similarity:	210/412 - (50%)	Gaps:	24/412 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SLKKLPVRMLANAARQQSAAMSSATGLPPPLTFLTDDEKMMKETVAKLAQEQIQPLVKKMDFEHK 68
            |:.|:..|.|::...|.:..:|..         ||:||:.:..:..:..||::.|.|.:.....|
Worm     8 SIGKIASRGLSSTFYQDAFQLSDQ---------LTEDERSLMLSAREYCQERLLPRVTEAYRTEK 63

  Fly    69 FDPSVVKAVFENGLMGIEIDTELGGSGCNFMTNI---VVVEELSKIDPAVAAFVDIHNTLVNSLM 130
            ||||::..:...||:|....    |.||...:.:   ::..|:.::|....:.:.:..:||...:
Worm    64 FDPSLIPEMGSMGLLGAPYQ----GYGCAGTSTVGYGLIAREVERVDSGYRSTMSVQTSLVIGPI 124

  Fly   131 IKFGNAEQKAKYLPKLAQ-EYAGSFALTEPGAGSDAFSLKTVAKKDGS--HYVINGSKMWISNSD 192
            ..:|:.:||.||:|.||. :..|.|.||||..||:...::|.|..|.:  .|.:||||.|||||.
Worm   125 YNYGSEDQKQKYIPDLASGKKIGCFGLTEPNHGSNPGGMETKATWDETTKTYKLNGSKTWISNSP 189

  Fly   193 VAGVFLIFA-NAKPEDGYRGITTFIVDRETPGLIVNKPEDKLGIRASGTCQLTFDNVRVPEENIL 256
            |:.|.:::| :|:..:..:|   ||::|...||...|.|.||.:|||.|.|:..|:|.|||||:|
Worm   190 VSDVMVVWARSARHNNKIKG---FILERGMKGLTTPKIEGKLSLRASITGQIAMDDVPVPEENLL 251

  Fly   257 GTFGHGYKYAAGFLNEGRIGIAAQMVGLAQGTFDATIPYLLERKQFGDAIYNFQSMQHQIATVAT 321
            .. ..|.:...|.||..|:|||...:|.|:..|.....|.|:|:|||..:...|.||.::|.:.|
Worm   252 PN-AEGLQGPFGCLNNARLGIAWGALGAAEECFHLARQYTLDRQQFGRPLAQNQLMQLKMADMLT 315

  Fly   322 EIEAARLMTYNAARLQEQGVPFQKEAAMAKYYASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRD 386
            ||..........:||:::|....::.::.|..:...|...|.|..|.:||.|...::...::..:
Worm   316 EISLGLQGCLRVSRLKDEGKVQSEQISIIKRNSCGKALEVARKARDMLGGNGIVDEYHIMRHMVN 380

  Fly   387 VKIGAIYEGTTNMQLSTIAKCI 408
            ::....||||.::....:.:.|
Worm   381 LETVNTYEGTHDVHALILGRAI 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	119/379 (31%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	117/377 (31%)
F54D5.7	NP_001369890.1	GCD	20..408	CDD:173840	121/400 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D589058at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820