DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and acdh-5

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_491942.1	Gene:	acdh-5 / 172400	WormBaseID:	WBGene00016491	Length:	442	Species:	Caenorhabditis elegans

Alignment Length:	415	Identity:	118/415 - (28%)
Similarity:	206/415 - (49%)	Gaps:	13/415 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 NSLKKLPVRMLANAARQQSAAMSSA---TGLPPPLTFLTDDEK--MMKETVAKLAQEQIQPLVKK 62
            |:|.|.....|.|..|..|.|::|.   :..|.....:..||.  :|::::.||.:|:|.|.|.|
Worm    20 NNLNKFRSSNLGNQRRSVSVAVTSTSPKSEKPVAREHMIYDETHFVMQKSLGKLIEEKINPNVAK 84

  Fly    63 MDFEHKFDPSVV-KAVFENGLMGIEIDTELGGSGCNFMTNIVVVEELSKID-PAVAAFVDIHNTL 125
            .:.:.::...:| |.:.::|:.|:......||:|.:......:.|::..|: .::...|.:...:
Worm    85 WEQDGRYPAHLVFKMLGDHGVFGVNKPEAFGGTGTDIAMATAIAEQMGAINCGSIPMSVMVQTDM 149

  Fly   126 VNSLMIKFGNAEQKAKYL-PKLAQEYAGSFALTEPGAGSDAFSLKTVAKKDGSHYVINGSKMWIS 189
            ....:.:||:...:.::| |.:..:...|.|::||.||||..::.|.|::.||..:||||||||:
Worm   150 STPALAQFGSDALRERFLRPSITGDLVSSLAVSEPHAGSDVSAVHTHARRQGSDLIINGSKMWIT 214

  Fly   190 NSDVAGVFLIFAN-AKPEDGYRGITTFIVDRETPGLIVNKPEDKLGIRASGTCQLTFDNVRVPEE 253
            |...|....:..| :...:.::..:...|..:..|:..:.|.||||:|:|.|.||.|::||||..
Worm   215 NGGQADWACVLVNTSNTSNVHKNKSLVCVPLDAVGVHRSTPLDKLGMRSSDTVQLFFEDVRVPSS 279

  Fly   254 NILGTFGHGYKYAAGFLNEGRIGIAAQMVGL--AQGTFDATIPYLLERKQFGDAIYNFQSMQHQI 316
            .|:|..|.|:.|.....|:.|:...|  |||  .|...|.||.|..:|..||..:.:.|.:|.|:
Worm   280 YIIGEEGRGFGYQMKQFNDERLVTVA--VGLLPLQKCIDETIEYARDRLLFGKTLLDQQYIQFQL 342

  Fly   317 ATVATEIEAARLMTYNAARLQEQGVPFQKEAAMAKYYASEVAQRAAIKCVDWMGGVGFTRDFPQE 381
            |.:..|:||.|.:.|.....:.:|.......||||.....:|:....:|:...||.|:..:....
Worm   343 AELEAELEATRALLYRTVLARSRGDDVSMLTAMAKLKIGRLARAITDQCLQVWGGAGYLNENGIS 407

  Fly   382 KYYRDVKIGAIYEGTTNMQLSTIAK 406
            :.:||.::.:|..|...:.:..|.|
Worm   408 RAFRDFRLFSIGAGCDEVMMRIIHK 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	108/378 (29%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	108/376 (29%)
acdh-5	NP_491942.1	CaiA	57..441	CDD:224871	108/378 (29%)
		Acyl-CoA_dh_N	60..174	CDD:280866	24/113 (21%)
		ACAD	149..430	CDD:173838	86/282 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D589058at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820