DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and acdh-1

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_001370604.1	Gene:	acdh-1 / 172358	WormBaseID:	WBGene00016943	Length:	427	Species:	Caenorhabditis elegans

Alignment Length:	385	Identity:	222/385 - (57%)
Similarity:	290/385 - (75%)	Gaps:	0/385 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 TGLPPPLTFLTDDEKMMKETVAKLAQEQIQPLVKKMDFEHKFDPSVVKAVFENGLMGIEIDTELG 92
            ||.|||:..||::|....:||.|.:::.::|||::||...|..|.|.:.||||||||:.:..|.|
Worm    39 TGTPPPVNLLTENELFFADTVRKFSKDVVKPLVREMDKYSKMSPIVTQGVFENGLMGVHVPEEYG 103

  Fly    93 GSGCNFMTNIVVVEELSKIDPAVAAFVDIHNTLVNSLMIKFGNAEQKAKYLPKLAQEYAGSFALT 157
            |||.:|...::|:|||:|.||:|:|.|.|||||..|::|.:|..|||.||||:|..:...||.::
Worm   104 GSGSSFFNAMIVIEELAKTDPSVSAMVGIHNTLPVSMIIDYGTEEQKLKYLPRLCSDSLASFCIS 168

  Fly   158 EPGAGSDAFSLKTVAKKDGSHYVINGSKMWISNSDVAGVFLIFANAKPEDGYRGITTFIVDRETP 222
            |.|||||||:|||:||:||.|::|:|:||||:||..|.||::||||.|...|:|||.|||:|...
Worm   169 ESGAGSDAFALKTIAKRDGDHFLISGTKMWITNSGEAQVFVVFANADPSQKYKGITCFIVERSAD 233

  Fly   223 GLIVNKPEDKLGIRASGTCQLTFDNVRVPEENILGTFGHGYKYAAGFLNEGRIGIAAQMVGLAQG 287
            ||.|:|.|||||||||.|||:.||||||.:..|||.:|.|||||...||.|||.|.|||:|||||
Worm   234 GLTVDKEEDKLGIRASSTCQVHFDNVRVHKSAILGEYGKGYKYAIECLNAGRIAIGAQMIGLAQG 298

  Fly   288 TFDATIPYLLERKQFGDAIYNFQSMQHQIATVATEIEAARLMTYNAARLQEQGVPFQKEAAMAKY 352
            .||.|||||.:|:|||..:.:||.:|||||...||||||||:.|||||::|.|:|:.:||||||.
Worm   299 CFDQTIPYLQQREQFGQRLIDFQGLQHQIAQARTEIEAARLLVYNAARMKEYGIPYVREAAMAKL 363

  Fly   353 YASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIGAIYEGTTNMQLSTIAKCIKKDY 412
            :||:||...:.:||.|:||||||::||.||:|||..||.|||||:|:||:||||.|..:|
Worm   364 FASQVATSTSAQCVKWLGGVGFTKEFPAEKFYRDAMIGEIYEGTSNIQLNTIAKLIDNEY 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	217/376 (58%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	214/370 (58%)
acdh-1	NP_001370604.1	SCAD_SBCAD	50..420	CDD:173847	213/369 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163674
Domainoid	1	1.000	204	1.000	Domainoid score	I1720
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1216
Inparanoid	1	1.050	465	1.000	Inparanoid score	I856
Isobase	1	0.950	-	0	Normalized mean entropy	S1951
OMA	1	1.010	-	-		QHG53594
OrthoDB	1	1.010	-	-		D331445at33208
OrthoFinder	1	1.000	-	-		FOG0000508
OrthoInspector	1	1.000	-	-		otm14107
orthoMCL	1	0.900	-	-		OOG6_102170
Panther	1	1.100	-	-	O	PTHR43884
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2781
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.860