DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and AgaP_AGAP001951

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	XP_321112.5	Gene:	AgaP_AGAP001951 / 1281174	VectorBaseID:	AGAP001951	Length:	404	Species:	Anopheles gambiae

Alignment Length:	419	Identity:	161/419 - (38%)
Similarity:	245/419 - (58%)	Gaps:	20/419 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MMNSLKKLPVRMLANAARQQSAAMSSATGLPPPLTFLTDDEKMMKETVAKLAQEQIQPLVKKMDF 65
            ||.:| ::..||   ..|.:|.:::|.:.||       |..:|:::|....|..::.|...:.|.
Mosquito     1 MMFAL-RIASRM---GQRVRSRSIASLSALP-------DTHQMLQKTCRDFADNELVPNAARFDR 54

  Fly    66 EHKFDPSVVKAVFENGLMGIEIDTELGGSGCNFMTNIVVVEELSKIDPAVAAFVDIHNTLVNSLM 130
            ||.:....::.:.|.|||.|.:..|.||:|.:::...:.:||:|:...:....:.::|:|....:
Mosquito    55 EHLYPAEQIRKMGELGLMAISVKEEYGGTGLDYVAYAIAMEEISRGCASAGVIMSVNNSLYLGPL 119

  Fly   131 IKFGNAEQKAKYLPKLAQEY-----AGSFALTEPGAGSDAFSLKTVAKKDGSHYVINGSKMWISN 190
            ..|||.:|:.||:    .||     .|.|||:|||.||||.:..|.|...|.|:|:||:|.||:|
Mosquito   120 THFGNEQQQQKYV----TEYTDGSRVGCFALSEPGNGSDAGAASTTATLKGDHWVLNGTKCWITN 180

  Fly   191 SDVAGVFLIFANAKPEDGYRGITTFIVDRETPGLIVNKPEDKLGIRASGTCQLTFDNVRVPEENI 255
            ...||..::||.......::||:.|||.:||||..:.|.|||||||.|.||.|.|::..:|.||:
Mosquito   181 GYEAGAAVVFATTDKSLKHKGISAFIVPKETPGFSLGKKEDKLGIRGSSTCSLIFEDCAIPRENL 245

  Fly   256 LGTFGHGYKYAAGFLNEGRIGIAAQMVGLAQGTFDATIPYLLERKQFGDAIYNFQSMQHQIATVA 320
            ||..|.|:|.|...|:.||||||:|.:|:||.:.:..:.|..:|..||..|...|::|.:||.:|
Mosquito   246 LGEPGFGFKIAMQTLDAGRIGIASQALGIAQASLECAVDYANKRIAFGKPIAKLQAIQTKIADMA 310

  Fly   321 TEIEAARLMTYNAARLQEQGVPFQKEAAMAKYYASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYR 385
            |.:|||||:|:.||.|::...||.||||.||..|||.|...|.:.:..:||:|:..|.|.|::||
Mosquito   311 TRLEAARLLTWRAAWLKDNKKPFTKEAAQAKLAASEAATYCAHQSIQVLGGMGYVSDMPAERHYR 375

  Fly   386 DVKIGAIYEGTTNMQLSTIAKCIKKDYAA 414
            |.:|..|||||:.:|...||..:.|:..|
Mosquito   376 DARITEIYEGTSEIQRLVIAGAVIKELTA 404

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	150/381 (39%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	149/375 (40%)
AgaP_AGAP001951	XP_321112.5	CaiA	26..404	CDD:224871	152/388 (39%)
AgaP_AGAP001951	XP_321112.5	SCAD_SBCAD	28..400	CDD:173847	149/375 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D589058at2759
OrthoFinder	1	1.000	-	-		FOG0000508
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820