DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3902 and AgaP_AGAP009783

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	XP_318878.3	Gene:	AgaP_AGAP009783 / 1279196	VectorBaseID:	AGAP009783	Length:	417	Species:	Anopheles gambiae

Alignment Length:	415	Identity:	308/415 - (74%)
Similarity:	348/415 - (83%)	Gaps:	13/415 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 RMLANAARQ-------------QSAAMSSATGLPPPLTFLTDDEKMMKETVAKLAQEQIQPLVKK 62
            :||.|..||             .|::..:|.....|||:|::||.:|||||||||||||.|||||
Mosquito     1 KMLQNVLRQVVRSVGSIGTRSFASSSFGTAKSATSPLTYLSEDEMVMKETVAKLAQEQIAPLVKK 65

  Fly    63 MDFEHKFDPSVVKAVFENGLMGIEIDTELGGSGCNFMTNIVVVEELSKIDPAVAAFVDIHNTLVN 127
            ||.||:||||||:|:|:|||||||:..|.|||.|||||.::|||||||:.||.||||||||||||
Mosquito    66 MDEEHQFDPSVVRALFDNGLMGIEVSDEYGGSACNFMTTMLVVEELSKVCPATAAFVDIHNTLVN 130

  Fly   128 SLMIKFGNAEQKAKYLPKLAQEYAGSFALTEPGAGSDAFSLKTVAKKDGSHYVINGSKMWISNSD 192
            |||||.|.||||:||||||:|||:|||||:||.||||||||||.|||||:||::||:||||||||
Mosquito   131 SLMIKLGTAEQKSKYLPKLSQEYSGSFALSEPSAGSDAFSLKTTAKKDGNHYILNGTKMWISNSD 195

  Fly   193 VAGVFLIFANAKPEDGYRGITTFIVDRETPGLIVNKPEDKLGIRASGTCQLTFDNVRVPEENILG 257
            ::|||||.|||.|..||||||||||:||..|..|.|.|.||||.|||||.|..||||||||||||
Mosquito   196 LSGVFLIMANANPSAGYRGITTFIVEREYEGFTVGKKESKLGICASGTCTLHMDNVRVPEENILG 260

  Fly   258 TFGHGYKYAAGFLNEGRIGIAAQMVGLAQGTFDATIPYLLERKQFGDAIYNFQSMQHQIATVATE 322
            .||.||:|||||||||||||.|||:|||||..||||||||||||||..:|:||||||||||:|||
Mosquito   261 EFGKGYQYAAGFLNEGRIGIGAQMIGLAQGCLDATIPYLLERKQFGSDLYSFQSMQHQIATIATE 325

  Fly   323 IEAARLMTYNAARLQEQGVPFQKEAAMAKYYASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDV 387
            ||||||:|||||||||.|.||.|:||||||||||||||..:||:|||||||||:||||||:|||.
Mosquito   326 IEAARLLTYNAARLQEAGAPFLKQAAMAKYYASEVAQRTTVKCIDWMGGVGFTKDFPQEKFYRDC 390

  Fly   388 KIGAIYEGTTNMQLSTIAKCIKKDY 412
            |||||||||||||||||||.:||:|
Mosquito   391 KIGAIYEGTTNMQLSTIAKVMKKEY 415

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	298/376 (79%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	294/370 (79%)
AgaP_AGAP009783	XP_318878.3	CaiA	40..409	CDD:224871	293/368 (80%)
AgaP_AGAP009783	XP_318878.3	SCAD_SBCAD	42..413	CDD:173847	294/370 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	260	1.000	Domainoid score	I4582
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1216
Inparanoid	1	1.050	620	1.000	Inparanoid score	I2294
OMA	1	1.010	-	-		QHG53594
OrthoDB	1	1.010	-	-		D331445at33208
OrthoFinder	1	1.000	-	-		FOG0000508
OrthoInspector	1	1.000	-	-		otm51024
Panther	1	1.100	-	-	LDO	PTHR43884
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2781
TreeFam	1	0.960	-	-
	13	12.940