DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3902 and Acox1

DIOPT Version :9

Sequence 1:	NP_649069.2	Gene:	CG3902 / 40059	FlyBaseID:	FBgn0036824	Length:	414	Species:	Drosophila melanogaster
Sequence 2:	NP_001258827.1	Gene:	Acox1 / 11430	MGIID:	1330812	Length:	661	Species:	Mus musculus

Alignment Length:	468	Identity:	103/468 - (22%)
Similarity:	164/468 - (35%)	Gaps:	107/468 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 RQQSAAMSSATGLPPPLTFLTDDEKMMKETVAKLAQEQIQPLV-KKMDFEH-------------- 67
            |::.||   ||..|..:|.:.|..   .|...:  :.:|:.|: ...||:|
Mouse     6 RKERAA---ATFNPELITHILDGS---PENTRR--RREIENLILNDPDFQHEDYNFLTRSQRYEV 62

  Fly    68 --KFDPSVVKAVFENGLMGIEIDTELGGSGCNFMTNIVVVEELSKIDPAVAAFVDIHNTLVNSLM 130
              |...::||.:.|.|:...|   |:.......|.|.|        :|....:.....||:|.
Mouse    63 AVKKSATMVKKMREFGIADPE---EIMWFKKLHMVNFV--------EPVGLNYSMFIPTLLNQ-- 114

  Fly   131 IKFGNAEQKAKYL-PKLAQEYAGSFALTEPGAGSDAFSLKTVAKKD--GSHYVINGS-----KMW 187
               |...|:.|:: |....:..|::|.||.|.|:....|:|.|..|  ...:::|..     |.|
Mouse   115 ---GTTAQQEKWMHPSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWW 176

  Fly   188 ------ISNSDVAGVFLIFANAKPEDGYRGITTFIV-------DRETPGLIVNKPEDKLGIRASG 239
                  .||..:     :.|.........|:..|:|       .:..||:.|.....|.|.....
Mouse   177 PGGLGKTSNHAI-----VLAQLITRGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMD 236

  Fly   240 TCQLTFDNVRVPEENIL---------GTFGH--GYKYAAG---FLNEGRIGIAAQMVGLAQGTFD 290
            ...|..||.|:|.||:|         ||:..  ..|...|   |:....:|.|||.:..|   ..
Mouse   237 NGYLKMDNYRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGSAAQSLSKA---CT 298

  Fly   291 ATIPYLLERKQF-------GDAIYNFQSMQHQIATVATEIEAARLM------TYNAARLQE---Q 339
            ..|.|...|:|.       ...|.:||:.|:::..:.....|...:      ||  .|:.|   |
Mouse   299 IAIRYSAVRRQSEIKRSEPEPQILDFQTQQYKLFPLLATAYAFHFLGRYIKETY--MRINESIGQ 361

  Fly   340 G----VP-FQKEAAMAKYYASEVAQRAAIKCVDWMGGVGFTRDFPQEKYYRDVKIGAIYEGTTNM 399
            |    :| .....|..|.:.:..|.....:|....||.|::........|........:||...:
Mouse   362 GDLSELPELHALTAGLKAFTTWTANAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTV 426

  Fly   400 QLSTIAKCIKKDY 412
            .:...|:.:.|.|
Mouse   427 MMLQTARFLMKIY 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3902	NP_649069.2	CaiA	37..414	CDD:224871	96/449 (21%)
CG3902	NP_649069.2	SCAD_SBCAD	39..410	CDD:173847	94/443 (21%)
Acox1	NP_001258827.1	AXO	3..638	CDD:173839	103/468 (22%)
Acox1	NP_001258827.1	Microbody targeting signal	659..661
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810