DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3961 and Acsbg1

DIOPT Version :9

Sequence 1:	NP_649067.2	Gene:	CG3961 / 40056	FlyBaseID:	FBgn0036821	Length:	704	Species:	Drosophila melanogaster
Sequence 2:	XP_030100613.1	Gene:	Acsbg1 / 94180	MGIID:	2385656	Length:	754	Species:	Mus musculus

Alignment Length:	777	Identity:	197/777 - (25%)
Similarity:	308/777 - (39%)	Gaps:	163/777 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 GGTLGTLTLGS------------------LAASVAYYFATRP-VPERPLV---PLENQSPL---- 72
            |.:|||....|                  |:.::.|....|| |....|:   .|..:||.
Mouse    28 GASLGTSQDNSQTRFVSRLLPGGPGCVRKLSLNLKYQQGIRPSVRSSSLIDGQTLSKESPSHGLE 92

  Fly    73 LEGPEQIHVSK-------FYKESKNG----KFVSYITENVRTLYQTFREGAYASNNGPCLGWRET 126
            |..||:...:.       .:....:|    :...:.|:...|::|.|.|......|...||::.
Mouse    93 LSAPEKARAASLDGAEEALWTTRADGRVRLRLEPFCTQRPYTVHQMFYEALDKYGNLSALGFKR- 156

  Fly   127 LTSPYQWINYDEALLRAKNFGAGMLALGARPKQLIGIYSQNRPEWILYEQGCYSFSLVVVPLYDT 191
             ...::.|:|.:..|.|:....|.|.||......:.|...|.|||.....|......:|..:|.|
Mouse   157 -KDKWERISYYQYYLIARKVAKGFLKLGLERAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTT 220

  Fly   192 LGPDACAFIIRQTDMQVVIVEDDGKAAMLLE--KAPRSLKIIVAIKPIRQTTLERARSRGIQIFS 254
            ..|:||.:|.......|::|:...:...:|:  |....||.:|..:       |....:...:::
Mouse   221 SSPEACQYISHDCRANVIVVDTQKQLEKILKIWKDLPHLKAVVIYQ-------EPPPKKMANVYT 278

  Fly   255 FIDVEKLGAKGNHPEVPPTAED----------LCTVCYTSGTTGNPKGVMLTHGNVVAGVCSVIL 309
            ..::.:||     .|||..|.|          .|.:.||||||||||||||:..|        |.
Mouse   279 MEELIELG-----QEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDN--------IT 330

  Fly   310 QMGDHRIRAGD---------VMVSFLPLAHMFERCCE--NGMYYVGGCVGFYSGDIKE--LTNDL 361
            ....:..:|||         |:||:|||:|:..:..:  .|:.: |..|.|...|..:  |.|.|
Mouse   331 WTARYGSQAGDIQPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQW-GAQVCFADPDALKGTLVNTL 394

  Fly   362 KMLKPTVMPAVPRLLNRVYDKIQNDISASG-LKRGLFNMAMRAKEKEIARGVLRRN-GC------ 418
            :.::||....|||:..::.::||...:.|| ::|.:...||..        .|.:| .|
Mouse   395 REVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSV--------TLEQNLTCPSNDLK 451

  Fly   419 ------WDKLVFKKVHQAFG-GNLRLMVVGSAPLAGNVLTFMRCALGCLVLEGYGQTECTGAITL 476
                  .|.||..:|.||.| ...:....|:||:......|. ..|...:..|||.:|.||
Mouse   452 PFTSRLADYLVLARVRQALGFAKCQKNFYGAAPMTAETQRFF-LGLNIRLYAGYGLSESTG---- 511

  Fly   477 TVQGDHVPNHVGPPVS------------CNAVKLVDVPEMEYFANQNT---GEVCVRGSNVFHGY 526
                   |:.:..|.:            |. ||||         ||:.   ||:|:.|..:|.||
Mouse   512 -------PHFMSSPYNYRLYSSGRVVPGCR-VKLV---------NQDADGIGEICLWGRTIFMGY 559

  Fly   527 YKDPEKTAEAIDSEGWHHTGDVGMWLPNGTLRIIDRRKHIFKLSQGEYIVPEKIENIYTLS-QYV 590
            ....:||.||||||||.||||:|....:|.|.|..|.|.:...:.||.:.|..||....:. ..:
Mouse   560 LNMEDKTCEAIDSEGWLHTGDMGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPII 624

  Fly   591 NQVYVYGE---------SLKSCIIAVVVPDTDVLKQWATE-----NNVRGTLSVLCNNKN--VKE 639
            :...:.|:         :||..:.......||.|.:.|.|     .:...|:|.:...::  |.:
Mouse   625 SSAMLIGDQRKFLSMLLTLKCTLDPETSEPTDSLTEQAVEFCQRVGSKASTVSEIVGQRDEAVYQ 689

  Fly   640 LIMNDMLNWGKQSGLKSFEQVKDIYLHPDPFSVQNGLLTPTFKAKRPQLKSYFKPQLEDMYK 701
            .|...:......:..:.:...|...|..| ||:..|.|.||.|.||..:...:|..::..|:
Mouse   690 AIHEGIQRVNANAAARPYHIQKWAILQRD-FSISGGELGPTMKLKRLTVLEKYKDIIDSFYQ 750

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3961	NP_649067.2	LC-FACS_euk	130..701	CDD:341250	170/642 (26%)
Acsbg1	XP_030100613.1	ACSBG_like	155..749	CDD:341256	170/647 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810