Protein Alignment CG3961 and FAA2

DIOPT Version :10

• Sequence 1: NP_649067.2
• Gene: CG3961 / 40056
• FlyBaseID: FBgn0036821
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_010931.3
• Gene: FAA2 / 856734
• SGDID: S000000817
• Length: 744
• Species: Saccharomyces cerevisiae
• Alignment Length: 710
• Identity: 221/710 - (31%)
• Similarity: 355/710 - (50%)
• Gaps: 106/710 - (14%)

  Fly    66 LENQSPLLEGPE-QIHVSKFYKESKNGK-FVSYITENVRTLYQTFREGAYASNNGPCLG------ 122
            |:.|:..:..|: :...|..|:.|.:.: .||.:.:|:||.|..|...|.......|||
Yeast    55 LKKQAVAISNPDNEAGFSSIYRSSLSSENLVSCVDKNLRTAYDHFMFSARRWPQRDCLGSRPIDK 119

  Fly   123 ----WRETLTSPYQWINYDEALLRAKNFGAGMLAL----GARPKQ----LIGIYSQNRPEWILYE 175
                |.||    :::.:|.....|..|.|:|:|:|    ..||.:    ::.|.|.|.|||||.:
Yeast   120 ATGTWEET----FRFESYSTVSKRCHNIGSGILSLVNTKRKRPLEANDFVVAILSHNNPEWILTD 180

  Fly   176 QGCYSFSLVVVPLYDTLGPDACAFIIRQTDMQVVIVEDDGKAAM--LLEKAPRSLKIIVAIKPIR 238
            ..|.::||....||:||||:...:|:..|:..::|.   .|:.|  :|:..| .:|.:..:..:.
Yeast   181 LACQAYSLTNTALYETLGPNTSEYILNLTEAPILIF---AKSNMYHVLKMVP-DMKFVNTLVCMD 241

  Fly   239 QTTLERAR--------------SRGIQIFSFIDVEKLGAKGNHPEVPPTAEDLCTVCYTSGTTGN 289
            :.|.:..|              :..|..||...||::|.....|.:|||.:.|.|:.:||||||.
Yeast   242 ELTHDELRMLNESLLPVKCNSLNEKITFFSLEQVEQVGCFNKIPAIPPTPDSLYTISFTSGTTGL 306

  Fly   290 PKGVMLTHGNVVAGVCSVI-----------LQMGDHRIRAGDVMVSFLPLAHMFERCCENGMYYV 343
            ||||.::|.|:.:|:....           .|:.|         :.||||||:|||........:
Yeast   307 PKGVEMSHRNIASGIAFAFSTFRIPPDKRNQQLYD---------MCFLPLAHIFERMVIAYDLAI 362

  Fly   344 GGCVGF-YSGDIKELTNDLKMLKPTVMPAVPRLLNRVYDKIQNDISASGLKRGLFNMAMRAKEKE 407
            |..:|| :..|...|..|||:|||..:..|||:|.|....|:|.:..|.::|.:.|..:.:|...
Yeast   363 GFGIGFLHKPDPTVLVEDLKILKPYAVALVPRILTRFEAGIKNALDKSTVQRNVANTILDSKSAR 427

  Fly   408 I-ARG----VLRRNGCWDKLVFKKVHQAFG-GNLRLMVVGSAPLAGNVLTFMRCALGCLVLEGYG 466
            . |||    .:.....:.:::..|:..:.| .|...::.||||::.:.|.|:|.||...:.:|||
Yeast   428 FTARGGPDKSIMNFLVYHRVLIDKIRDSLGLSNNSFIITGSAPISKDTLLFLRSALDIGIRQGYG 492

  Fly   467 QTECTGAITLTVQGDHVPNHVGPPVSCNAV------KLVDVPEMEYFANQN-TGEVCVRGSNVFH 524
            .||....:.|:   :.....||   ||.|:      :|..||||.|.|::: .||:.:||..||.
Yeast   493 LTETFAGVCLS---EPFEKDVG---SCGAIGISAECRLKSVPEMGYHADKDLKGELQIRGPQVFE 551

  Fly   525 GYYKDPEKTAEAIDSEGWHHTGDVGMWLPNGTLRIIDRRKHIFKLSQGEYIVPEKIENIYTLS-Q 588
            .|:|:|.:|::|:|.:||..||||......|.:.:|||.|:.|||:.||||.||||||||..| .
Yeast   552 RYFKNPNETSKAVDQDGWFSTGDVAFIDGKGRISVIDRVKNFFKLAHGEYIAPEKIENIYLSSCP 616

  Fly   589 YVNQVYVYGESLKSCIIAVVVPDTDV-----------LKQWATENNVRGTLSVLCNNKNVKELIM 642
            |:.|::|:|:.||:.::.:|..|.|.           :|.|..|        ||..|.|..:.:.
Yeast   617 YITQIFVFGDPLKTFLVGIVGVDVDAAQPILAAKHPEVKTWTKE--------VLVENLNRNKKLR 673

  Fly   643 NDMLNWGKQ--SGLKSFEQVKDIYLHPDPFSVQNGLLTPTFKAKRPQLKSYFKPQLEDMY 700
            .:.||...:  .||:.||::.:|.:..:|.::::.::|||||.||.:...:||..|:.:|
Yeast   674 KEFLNKINKCTDGLQGFEKLHNIKVGLEPLTLEDDVVTPTFKIKRAKASKFFKDTLDQLY 733

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3961	NP_649067.2	LC-FACS_euk	130..701	CDD:341250	201/634 (32%)
FAA2	NP_010931.3	LC-FACS_euk	126..734	CDD:341250	203/639 (32%)