Protein Alignment CG3961 and FAA4

DIOPT Version :10

• Sequence 1: NP_649067.2
• Gene: CG3961 / 40056
• FlyBaseID: FBgn0036821
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_013974.1
• Gene: FAA4 / 855288
• SGDID: S000004860
• Length: 694
• Species: Saccharomyces cerevisiae
• Alignment Length: 695
• Identity: 207/695 - (29%)
• Similarity: 326/695 - (46%)
• Gaps: 112/695 - (16%)

  Fly    89 KNGKFVSYITENVRTLY----QTFREGAYASNNGPCLGWRETL---------------------- 127
            |:...:..|..:..|||    :.|.:|  ...:|  :.||:.:
Yeast    27 KDQPLIRPINSSASTLYEFALECFTKG--GKRDG--MAWRDIIDIHETKKTIVKRVDGKDKPIEK 87

  Fly   128 ------TSPYQWINYDEALLRAKNFGAGMLALGARP--KQLIGIYSQNRPEWILYEQGCYSFSLV 184
                  .:||..:.|:|.:....:.|.|::.:|.:|  :....|::....:|:....||.|..:.
Yeast    88 TWLYYELTPYITMTYEEMICVMHDIGRGLIKIGVKPNGENKFHIFASTSHKWMKTFLGCMSQGIP 152

  Fly   185 VVPLYDTLGPDACAFIIRQTDMQVVIVEDD--GKAAMLLEKAPRSLKIIVAIKPI-----RQT-- 240
            ||..|||||.......:.:||...:..::.  .|.|:.| |..:::|.::..:||     ||.
Yeast   153 VVTAYDTLGESGLIHSMVETDSVAIFTDNQLLSKLAVPL-KTAKNVKFVIHNEPIDPSDKRQNGK 216

  Fly   241 ----------TLERARSRGIQIFSFIDVEKLGAKGNHPEVP---PTAEDLCTVCYTSGTTGNPKG 292
                      .::..|. .|:|:||.::.::|.|.. .||.   |..||...:.||||:||.|||
Yeast   217 LYKAAKDAVDKIKEVRP-DIKIYSFDEIIEIGKKAK-DEVELHFPKPEDPACIMYTSGSTGTPKG 279

  Fly   293 VMLTHGNVVAGVCSVILQMGDHR----IRAGDVMVSFLPLAHMFERCCENGMYYVGGCVGFYSGD 353
            |:|||.|:|||:..|     .|.    |...|.:::||||||:||...|...:|..|.:|:  .:
Yeast   280 VVLTHYNIVAGIGGV-----GHNVIGWIGPTDRIIAFLPLAHIFELTFEFEAFYWNGILGY--AN 337

  Fly   354 IKELT--------NDLKMLKPTVMPAVPRLLNRVYDKIQNDISAS-----GLKRGLFNMAMRAKE 405
            :|.||        .||...|||||..|.    .|::.::..|.|.     |..:.||......||
Yeast   338 VKTLTPTSTRNCQGDLMEFKPTVMVGVA----AVWETVRKGILAKINELPGWSQTLFWTVYALKE 398

  Fly   406 KEIARGVLRRNGCWDKLVFKKVHQAFGGNLRLMVVGSAPLAGNVLTFMRCALGCLVLEGYGQTE- 469
            :.|.     .:|....|:||::.:|.|||||.::.|.:.::.:...|:...| |.:|.|||.||
Yeast   399 RNIP-----CSGLLSGLIFKRIREATGGNLRFILNGGSAISIDAQKFLSNLL-CPMLIGYGLTEG 457

  Fly   470 CTGAITLTVQGDHVPNH-----VGPPVSCNAVKLVDVPEMEYFANQNTGEVCVRGSNVFHGYYKD 529
            ...|..|.      |.|     .|..|.....|||||.::.|||..|.||:..:|:.:...|||:
Yeast   458 VANACVLE------PEHFDYGIAGDLVGTITAKLVDVEDLGYFAKNNQGELLFKGAPICSEYYKN 516

  Fly   530 PEKTAEAIDSEGWHHTGDVGMWLPNGTLRIIDRRKHIFKLSQGEYIVPEKIENIYTLSQYVNQVY 594
            ||:||.|...:||..|||:..|.|.|.::||||:|::.|...||||..||:|:||..:.||..:.
Yeast   517 PEETAAAFTDDGWFRTGDIAEWTPKGQVKIIDRKKNLVKTLNGEYIALEKLESIYRSNPYVQNIC 581

  Fly   595 VYGESLKSCIIAVVVPDTDVLKQWATENNVR---GTLSVLCNNKNVKELIMNDMLNWGKQSGLKS 656
            ||.:..|...:.:|||:...|.:.|.|..:.   ..:....:.|.:::.:..|||:..|..||..
Yeast   582 VYADENKVKPVGIVVPNLGHLSKLAIELGIMVPGEDVESYIHEKKLQDAVCKDMLSTAKSQGLNG 646

  Fly   657 FEQVKDIYLHPDPFSVQNGLLTPTFKAKRPQLKSYFKPQLEDMYK 701
            .|.:..|....:.::.:|||:|...|.||..:.:..||.:|.:||
Yeast   647 IELLCGIVFFEEEWTPENGLVTSAQKLKRRDILAAVKPDVERVYK 691

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3961	NP_649067.2	LC-FACS_euk	130..701	CDD:341250	195/620 (31%)
FAA4	NP_013974.1	LC_FACS_euk1	96..678	CDD:341294	192/607 (32%)
		PRK04319	<230..>285	CDD:235279	24/56 (43%)