DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3961 and LACS6

DIOPT Version :9

Sequence 1:	NP_649067.2	Gene:	CG3961 / 40056	FlyBaseID:	FBgn0036821	Length:	704	Species:	Drosophila melanogaster
Sequence 2:	NP_566265.1	Gene:	LACS6 / 819767	AraportID:	AT3G05970	Length:	701	Species:	Arabidopsis thaliana

Alignment Length:	673	Identity:	272/673 - (40%)
Similarity:	387/673 - (57%)	Gaps:	37/673 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 LVPLENQSPLLEG-----------------PEQIHVSKF--YKESKNG-KFVSYITE--NVRTLY 105
            ||.....||||..                 ||:::...:  |:.:|:. |.||...:  ::.||:
plant    23 LVTSSRSSPLLRSNPTAGEFCLDNGYSVVLPEKLNTGSWNVYRSAKSPFKLVSRFPDHPDIATLH 87

  Fly   106 QTFREGAYASNNGPCLGWR---ETLTSPYQWINYDEALLRAKNFGAGMLALGARPKQLIGIYSQN 167
            ..|....:...:...||.|   :.....|:|:.|.||.......|:|::..|......:|||..|
plant    88 DNFEHAVHDFRDYKYLGTRVRVDGTVGDYKWMTYGEAGTARTALGSGLVHHGIPMGSSVGIYFIN 152

  Fly   168 RPEWILYEQGCYSFSLVVVPLYDTLGPDACAFIIRQTDMQVV--IVEDDGKAAMLLEKAPRSLKI 230
            ||||::.:..|.|:|.|.|||||||||||..||:....:|.:  :.|........|.:.| |:::
plant   153 RPEWLIVDHACSSYSYVSVPLYDTLGPDAVKFIVNHATVQAIFCVAETLNSLLSCLSEMP-SVRL 216

  Fly   231 IVAIKPIRQTTLERARSRGIQIFSFIDVEKLGAKGNHPEVPPTAEDLCTVCYTSGTTGNPKGVML 295
            :|.:..:.::......|.|:::.|:..:...|........||..:|:.|:||||||||.||||:|
plant   217 VVVVGGLIESLPSLPSSSGVKVVSYSVLLNQGRSNPQRFFPPKPDDVATICYTSGTTGTPKGVVL 281

  Fly   296 THGNVVAGVCSVILQMGDHRIRAGDVMVSFLPLAHMFERCCENGMYYVGGCVGFYSGDIKELTND 360
            ||.|::|.|......:   :..:.||.:|:|||||::||..:....|.|..||||.||..:|.:|
plant   282 THANLIANVAGSSFSV---KFFSSDVYISYLPLAHIYERANQILTVYFGVAVGFYQGDNMKLLDD 343

  Fly   361 LKMLKPTVMPAVPRLLNRVYDKIQNDISAS-GLKRGLFNMAMRAKEKEIARGVLRRNGCWDKLVF 424
            |..|:|||..:||||.||:|..|.|.:..| |||..|||.|..||::.:..| ...:..||:|||
plant   344 LAALRPTVFSSVPRLYNRIYAGIINAVKTSGGLKERLFNAAYNAKKQALLNG-KSASPIWDRLVF 407

  Fly   425 KKVHQAFGGNLRLMVVGSAPLAGNVLTFMRCALGCLVLEGYGQTECTGAITLTVQGDHVPNHVGP 489
            .|:....||.:|.|..|::||:..|:.|::...|..|.||||.||.:..|:...:||::..|||.
plant   408 NKIKDRLGGRVRFMTSGASPLSPEVMEFLKVCFGGRVTEGYGMTETSCVISGMDEGDNLTGHVGS 472

  Fly   490 PVSCNAVKLVDVPEMEYFANQN---TGEVCVRGSNVFHGYYKDPEKTAEAIDSEGWHHTGDVGMW 551
            |.....|||||||||.|.:...   .||:||||..:|.|||||..:|.|.||.:||.||||:|:|
plant   473 PNPACEVKLVDVPEMNYTSADQPHPRGEICVRGPIIFTGYYKDEIQTKEVIDEDGWLHTGDIGLW 537

  Fly   552 LPNGTLRIIDRRKHIFKLSQGEYIVPEKIENIYTLSQYVNQVYVYGESLKSCIIAVVVPDTDVLK 616
            ||.|.|:||||:|:||||:|||||.||||||:|...::|.|.::||:|..|.::|||..|.||||
plant   538 LPGGRLKIIDRKKNIFKLAQGEYIAPEKIENVYAKCKFVGQCFIYGDSFNSSLVAVVSVDPDVLK 602

  Fly   617 QWATENNVR-GTLSVLCNNKNVKELIMNDMLNWGKQSGLKSFEQVKDIYLHPDPFSVQNGLLTPT 680
            .||....:: |.|..||||..||..:::||...|:::.|:.||..|.:.|..:||:::|||||||
plant   603 SWAASEGIKGGDLRELCNNPRVKAAVLSDMDTVGREAQLRGFEFAKAVTLVLEPFTLENGLLTPT 667

  Fly   681 FKAKRPQLKSYFKPQLEDMYKHL 703
            ||.||||.|.||...:.:|||.|
plant   668 FKIKRPQAKEYFAEAITNMYKEL 690

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3961	NP_649067.2	LC-FACS_euk	130..701	CDD:341250	250/577 (43%)
LACS6	NP_566265.1	PLN02736	41..691	CDD:178337	266/655 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	370	1.000	Domainoid score	I177
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69208
Inparanoid	1	1.050	500	1.000	Inparanoid score	I318
OMA	1	1.010	-	-		QHG53493
OrthoDB	1	1.010	-	-		D630541at2759
OrthoFinder	1	1.000	-	-		FOG0000532
OrthoInspector	1	1.000	-	-		otm3365
orthoMCL	1	0.900	-	-		OOG6_100152
Panther	1	1.100	-	-	O	PTHR43272
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X329
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840