Protein Alignment CG3961 and ACSBG2

DIOPT Version :10

• Sequence 1: NP_649067.2
• Gene: CG3961 / 40056
• FlyBaseID: FBgn0036821
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_112186.3
• Gene: ACSBG2 / 81616
• HGNCID: 24174
• Length: 666
• Species: Homo sapiens
• Alignment Length: 690
• Identity: 167/690 - (24%)
• Similarity: 299/690 - (43%)
• Gaps: 113/690 - (16%)

  Fly    63 LVPLENQSPLLEGPEQIHVSKFYKESKNGKFVSYITENVRTLYQTFREGAYASNNGPCLGWRETL 127
            |:.|....|..|.|  :.:.:|::||.| :|.:|              .|.||.||
Human    37 LLRLSKHGPGHETP--MTIPEFFRESVN-RFGTY--------------PALASKNG--------- 75

  Fly   128 TSPYQWINYDEALLRAKNFGAGMLALGARPKQLIGIYSQNRPEWILYEQGCYSFSLVVVPLYDTL 192
             ..::.:|:::.....:.....::.||......:||...|..||.:...|......:.|.:|.|.
Human    76 -KKWEILNFNQYYEACRKAAKSLIKLGLERFHGVGILGFNSAEWFITAVGAILAGGLCVGIYATN 139

  Fly   193 GPDACAFIIRQTDMQVVIVEDDGKAAMLLEKAPRSLKIIVAIKPIRQTTLERARSRGIQIFSFID 257
            ..:.|.::|....:.:::||:|.:...:|.....||:   .:|.|.|..|...::.  .::|:.|
Human   140 SAEVCQYVITHAKVNILLVENDQQLQKILSIPQSSLE---PLKAIIQYRLPMKKNN--NLYSWDD 199

  Fly   258 VEKLGAKGNHPEVPPT----------AEDLCTVCYTSGTTGNPKGVMLTHGNV--VAGVCSVILQ 310
            ..:||.     .:|.|          |.....:.|||||||.||||||:|.|:  :||..:...:
Human   200 FMELGR-----SIPDTQLEQVIESQKANQCAVLIYTSGTTGIPKGVMLSHDNITWIAGAVTKDFK 259

  Fly   311 MGDHRIRAGDVMVSFLPLAHMFERCCENGM-YYVGGCVGFYSGDIKE--LTNDLKMLKPTVMPAV 372
            :.|..    :.:||:|||:|:..:..:..: ..:|....|...|..:  |.:.||.:||||...|
Human   260 LTDKH----ETVVSYLPLSHIAAQMMDIWVPIKIGALTYFAQADALKGTLVSTLKEVKPTVFIGV 320

  Fly   373 PRLLNRVYDKI-QNDISASGLKRGLF----NMAMRAKEKEIARGVLRRNGCWD---------KLV 423
            |::..::::.: :|...:.|||:..|    |:..:...|::.       |.::         .||
Human   321 PQIWEKIHEMVKKNSAKSMGLKKKAFVWARNIGFKVNSKKML-------GKYNTPVSYRMAKTLV 378

  Fly   424 FKKVHQAFG-GNLRLMVVGSAPLAGNVLTFMRCALGCLVLEGYGQTECTGAITLTVQGDHVPNHV 487
            |.||..:.| .:....:.|:|||......|. .:|...:.|.||.:|.:|..|::.|.::
Human   379 FSKVKTSLGLDHCHSFISGTAPLNQETAEFF-LSLDIPIGELYGLSESSGPHTISNQNNY----- 437

  Fly   488 GPPVSCNAVKLVDVPEMEYFANQN-TGEVCVRGSNVFHGYYKDPEKTAEAIDSEGWHHTGDVGMW 551
             ..:||..: |.....|.:..|:: .||:|:.|.::|.||.:...:|.||||.|||.|:||:|..
Human   438 -RLLSCGKI-LTGCKNMLFQQNKDGIGEICLWGRHIFMGYLESETETTEAIDDEGWLHSGDLGQL 500

  Fly   552 LPNGTLRIIDRRKHIFKLSQGEYIVPEKIENIYTLS-QYVNQVYVYGESLKSCIIAVVVPDTDVL 615
            ...|.|.:....|.|...:.||.:.|..:|.:.... ..::...:.|:.||  .:::::.....:
Human   501 DGLGFLYVTGHIKEILITAGGENVPPIPVETLVKKKIPIISNAMLVGDKLK--FLSMLLTLKCEM 563

  Fly   616 KQWATE----------NNVRGTLSVLCNNKNVKELI----------MNDMLNWGKQSGLKSFEQV 660
            .|.:.|          |..||..|   ....|.|::          :...:|...|..:.:.:::
Human   564 NQMSGEPLDKLNFEAINFCRGLGS---QASTVTEIVKQQDPLVYKAIQQGINAVNQEAMNNAQRI 625

  Fly   661 KDIYLHPDPFSVQNGLLTPTFKAKRPQLKSYFKPQLEDMY 700
            :...:....||:..|.|.|..|.||..:...:|.|::.||
Human   626 EKWVILEKDFSIYGGELGPMMKLKRHFVAQKYKKQIDHMY 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3961	NP_649067.2	LC-FACS_euk	130..701	CDD:341250	151/623 (24%)
ACSBG2	NP_112186.3	ACSBG_like	73..665	CDD:341256	151/635 (24%)