Protein Alignment CG3961 and hll

DIOPT Version :10

• Sequence 1: NP_649067.2
• Gene: CG3961 / 40056
• FlyBaseID: FBgn0036821
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_609696.1
• Gene: hll / 34822
• FlyBaseID: FBgn0286723
• Length: 681
• Species: Drosophila melanogaster
• Alignment Length: 680
• Identity: 179/680 - (26%)
• Similarity: 287/680 - (42%)
• Gaps: 114/680 - (16%)

  Fly   102 RTLYQTFREGAYASNNGPCLGWRETLTSPYQW--INYDEALLRAKNFGAGMLALGARPKQLIGIY 164
            :|:.:.|:|.....::.|.|.|....:....|  :.:.|...|.:.....:|::|...:..:||.
  Fly    36 QTIPEFFKESCEKYSDLPALVWETPGSGNDGWTTLTFGEYQERVEQAALMLLSVGVEERSSVGIL 100

  Fly   165 SQNRPEWILYEQGCYSFSLVVVPLYDTLGPDACAFIIRQTDMQVVIVEDDGKAAML---LEKAPR 226
            :.|.|||...|.|......||..:|.:...:|...::...:..|.:|:|..:.|.|   .|:.||
  Fly   101 AFNCPEWFFAEFGALRAGAVVAGVYPSNSAEAVHHVLATGESSVCVVDDAQQMAKLRAIKERLPR 165

  Fly   227 SLKIIVAIKPIRQTTLERA------RSRGIQIFSFIDVEKLGAKGNHPEVPPTAEDLCTVCYTSG 285
             ||.::.:....:..::..      :....|.||....|:|.|:    |....|.:...:.:|||
  Fly   166 -LKAVIQLHGPFEAFVDHEPGYFSWQKLQEQTFSSELKEELLAR----ESRIRANECAMLIFTSG 225

  Fly   286 TTGNPKGVMLTHGNVVAGVCSVILQMGDHRIRAG-DVMVSFLPLAHMFERCCENGMYYVG----G 345
            |.|.||.|||:|.|:|....|....|.|  |:.| :..||:|||:|:..:..:   .::|    |
  Fly   226 TVGMPKAVMLSHDNLVFDTKSAAAHMQD--IQVGKESFVSYLPLSHVAAQIFD---VFLGLSHAG 285

  Fly   346 CVGFYSGDIKE--LTNDLKMLKPTVMPAVPRLLNRVYDKIQNDISASGLKRGLFNMAMRAKEKEI 408
            ||.|...|..:  |....:..:||.|..||    ||::|:|..:.|:..|...::..:.|:
  Fly   286 CVTFADKDALKGTLIKTFRKARPTKMFGVP----RVFEKLQERLVAAEAKARPYSRLLLAR---- 342

  Fly   409 ARGVLRRN--------------------GCWDKLVFKKVHQAFG-GNLRLMVVGSAPLAGNVLTF 452
            ||..:..:                    .|   .|.|.:.:..| .|.|:...|.||.:..:..|
  Fly   343 ARAAVAEHQTTLMAGKSPSIYGNAKYWLAC---RVVKPIREMIGVDNCRVFFTGGAPTSEELKQF 404

  Fly   453 ---MRCALGCLVLEGYGQTECTGAITLTVQGDHVPNHVGPPVSCNAVKL-VDVPEMEYFANQNTG 513
               :..|||    |.||.:|.:|||||.|.   :.|......:|..|.| :..|:.     ...|
  Fly   405 FLGLDIALG----ECYGMSETSGAITLNVD---ISNLYSAGQACEGVTLKIHEPDC-----NGQG 457

  Fly   514 EVCVRGSNVFHGYYKDPEKTAEAIDSEGWHHTGDVGMWLPNGTLRIIDRRKHIFKLSQGEYIVPE 578
            |:.:||..||.||...|:||.|.:..:||.|:||:|...|.|.|.|..|.|.:...:.||.|.|.
  Fly   458 EILMRGRLVFMGYLGLPDKTEETVKEDGWLHSGDLGYIDPKGNLIISGRLKELIITAGGENIPPV 522

  Fly   579 KIENIYTLS-QYVNQVYVYGE---------SLKS-CIIAVVVPDTDVLK----QWATENNVRGT- 627
            .||.:.... ..|:.|.:.|:         |||: |.....:| .|.|:    :|..:.::..|
  Fly   523 HIEELIKKELPCVSNVLLIGDHRKYLTVLLSLKTKCDAKTGIP-LDALREETIEWLRDLDIHETR 586

  Fly   628 LSVLCN--------NKNVK-----ELIMNDMLNWGKQSGLK--------SFEQVKDIYLHPDPFS 671
            ||.|.|        |....     |:.....|....:.|:|        :.::|:...|....||
  Fly   587 LSELLNIPADLQLPNDTAALAATLEITAKPKLLEAIEEGIKRANKYAISNAQKVQKFALIAHEFS 651

  Fly   672 VQNGLLTPTFKAKRPQLKSYFKPQLEDMYK 701
            |..|.|.||.|.:|..:.:.:...:|.:||
  Fly   652 VATGELGPTLKIRRNIVHAKYAKVIERLYK 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3961	NP_649067.2	LC-FACS_euk	130..701	CDD:341250	171/650 (26%)
hll	NP_609696.1	Adenylate forming domain, Class I superfamily	62..680	CDD:473059	171/651 (26%)