Protein Alignment CG3961 and lcf2

DIOPT Version :10

• Sequence 1: NP_649067.2
• Gene: CG3961 / 40056
• FlyBaseID: FBgn0036821
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_596185.1
• Gene: lcf2 / 2541350
• PomBaseID: SPBP4H10.11C
• Length: 689
• Species: Schizosaccharomyces pombe
• Alignment Length: 612
• Identity: 193/612 - (31%)
• Similarity: 309/612 - (50%)
• Gaps: 44/612 - (7%)

  Fly   123 WRETLTSPYQWINYDEALLRAKNFGAGMLALGARPKQLIGIYSQNRPEWILYEQGCYSFSLVVVP 187
            |......||::|::::....|...|:|::|.|...:..:..::....:|....|||.|.::.:|.
pombe    90 WTTYELGPYEYISFNKVYEIALALGSGLVASGITSETTMLFFAATSAKWFTTAQGCSSQAIPIVT 154

  Fly   188 LYDTLGPDACAFIIRQTDMQVVIVEDDGKAAMLLEKAPRS--LKIIVAIKPIRQTTLERARSRG- 249
            .|:|||.|.....:.:...:.:.. |......||....:|  :|:||......:..:|..:|..
pombe   155 AYETLGEDGIYTSLDECKSRAIFT-DPNLIPKLLGPLKQSTWVKLIVCSSTPSEDLVELVKSTAP 218

  Fly   250 -IQIFSFIDVEKLGAKGNHPEVPPTAEDLCTVCYTSGTTGNPKGVMLTHGNVVAGVCSVILQMGD 313
             ::|.::.::..||.:...|..||.|:|:|...||||:||.||||:|.|.|::|.:..:...:..
pombe   219 DVEIITYDNLLSLGKEKPQPPHPPKADDICCYMYTSGSTGKPKGVVLLHRNIIAALGGINRILSQ 283

  Fly   314 HRIRAGDVMVSFLPLAH----MFERCCENGMYYVGGCVGFYS------GDIKELTNDLKMLKPTV 368
            | |...|.::::|||||    :||.||    .|.||.:|:.|      ..:.....||...:|||
pombe   284 H-INVKDYVLAYLPLAHIFEFIFEMCC----LYWGGVLGYASPRTLTDASVVNCKGDLTEFRPTV 343

  Fly   369 MPAVPRLLNRVYDKIQNDI-----SASGLKRGLFNMAMRAKEKEIARGVLRRNGCWDKLVFKKVH 428
            :..||    .||:.|:..|     |....::.:|:.::..|:..|.|. |..:...|.:||.||.
pombe   344 LIGVP----AVYELIKKGILAKVSSMPAHRQKVFSGSLSLKQYLIERN-LPGSAALDAIVFNKVK 403

  Fly   429 QAFGGNLRLMVVGSAPLAGNVLTFMRCALGCLVLEGYGQTE-CTGAITLTVQGDHV-PNHVGPPV 491
            .|.||.||..:.|.|.||.:...|:...: |.||.|||.|| |.|:..|:.:..|: .|.||.|:
pombe   404 AATGGRLRYCISGGAALAASTQAFLSSCI-CPVLPGYGLTETCAGSFVLSPEQWHLYANTVGFPI 467

  Fly   492 SCNAVKLVDVPEMEYFANQN--TGEVCVRGSNVFHGYYKDPEKTAEAIDSEGWHHTGDVGMWLPN 554
            .....||||:|::.|:.:.:  .|||.:||..|.:||...||....|...:||..|||||.....
pombe   468 PSIEFKLVDIPDLGYYTDSSPPRGEVWIRGPAVCNGYLNRPEDNKAAFTEDGWFKTGDVGEIAKG 532

  Fly   555 GTLRIIDRRKHIFKLSQGEYIVPEKIENIYTLSQYVNQVYVYGESLKSCIIAVVVPDTDVLKQWA 619
            .|||:|||:|:|.|...||||..||||..:..|..|:.|..|.:...:..:.:|.||.:.|:.:.
pombe   533 NTLRLIDRKKNIVKSLNGEYIALEKIEAQFFTSPLVSNVCAYADVNHAKPVVIVNPDENGLRTYL 597

  Fly   620 TEN-------NVRGTLSVLCNNKNVKELIMNDMLNWGKQSGLKSFEQVKDIYLHPDPFSVQNGLL 677
            |:|       |...||:.||.:..|:.||:.:::|.|||..|.|.|..:.:.|....::.:|..|
pombe   598 TKNSGSSFNGNPNDTLTNLCKDSGVQHLILKELINIGKQQRLASIEIPEGVVLSDFEWTAENNFL 662

  Fly   678 TPTFKAKRPQLKSYFKPQLEDMY--KH 702
            |.:.|.||..:.:::..:::..|  ||
pombe   663 TASRKVKRQVIVAHYSDEIQKAYSKKH 689

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3961	NP_649067.2	LC-FACS_euk	130..701	CDD:341250	190/602 (32%)
lcf2	NP_596185.1	LC_FACS_euk1	96..673	CDD:341294	189/588 (32%)
		Adenylate forming domain, Class I superfamily	<149..>267	CDD:473059	35/118 (30%)