Protein Alignment CG3961 and ACSL6

DIOPT Version :9

• Sequence 1: NP_649067.2
• Gene: CG3961 / 40056
• FlyBaseID: FBgn0036821
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_001009185.1
• Gene: ACSL6 / 23305
• HGNCID: 16496
• Length: 722
• Species: Homo sapiens
• Alignment Length: 672
• Identity: 338/672 - (50%)
• Similarity: 457/672 - (68%)
• Gaps: 20/672 - (2%)

  Fly    40 LTLGSLAASVAYYFATRPVPERPLVPLENQSPLLEGPEQIHVSKFYKESKNG---KFVSYITENV 101
            :::|:|||.:||:|..||...:|...|..||      |::..|...:.|..|   :.:::..::.
Human    56 VSMGALAAILAYWFTHRPKALQPPCNLLMQS------EEVEDSGGARRSVIGSGPQLLTHYYDDA 114

  Fly   102 RTLYQTFREGAYASNNGPCLGWRETLTSPYQWINYDEALLRAKNFGAGMLALGAR--PKQLIGIY 164
            ||:||.||.|...|.||||||:|:. ..||||::|.|...||:..|:|:|....:  ..|.||::
Human   115 RTMYQVFRRGLSISGNGPCLGFRKP-KQPYQWLSYQEVADRAEFLGSGLLQHNCKACTDQFIGVF 178

  Fly   165 SQNRPEWILYEQGCYSFSLVVVPLYDTLGPDACAFIIRQTDMQVVIVEDDGKAAMLLEKAPR--- 226
            :|||||||:.|..||::|:|||||||||||.|..:||...|:..|||:...||.:|||...|
Human   179 AQNRPEWIIVELACYTYSMVVVPLYDTLGPGAIRYIINTADISTVIVDKPQKAVLLLEHVERKET 243

  Fly   227 -SLKIIVAIKPIRQTTLERARSRGIQIFSFIDVEKLGAKGNHPEVPPTAEDLCTVCYTSGTTGNP 290
             .||:|:.:.|..:...||.:..|:.|.|...||..|.:.:...|||..:||..||:||||||||
Human   244 PGLKLIILMDPFEEALKERGQKCGVVIKSMQAVEDCGQENHQAPVPPQPDDLSIVCFTSGTTGNP 308

  Fly   291 KGVMLTHGNVVAGVCSVILQMGDHRI--RAGDVMVSFLPLAHMFERCCENGMYYVGGCVGFYSGD 353
            ||.|||||||||.. |..|::.:..|  |..||::|||||||||||..::.:|..||.|||:.||
Human   309 KGAMLTHGNVVADF-SGFLKVTEKVIFPRQDDVLISFLPLAHMFERVIQSVVYCHGGRVGFFQGD 372

  Fly   354 IKELTNDLKMLKPTVMPAVPRLLNRVYDKIQNDISASGLKRGLFNMAMRAKEKEIARGVLRRNGC 418
            |:.|::|:|.|.||:.|.|||||||:||||.:..: :.|||.|...|.:.|:.|:..|::|.:..
Human   373 IRLLSDDMKALCPTIFPVVPRLLNRMYDKIFSQAN-TPLKRWLLEFAAKRKQAEVRSGIIRNDSI 436

  Fly   419 WDKLVFKKVHQAFGGNLRLMVVGSAPLAGNVLTFMRCALGCLVLEGYGQTECTGAITLTVQGDHV 483
            ||:|.|.|:..:.||.:|::|.|:||.:..||.|:|.||||.|.|||||||||...|.|..||..
Human   437 WDELFFNKIQASLGGCVRMIVTGAAPASPTVLGFLRAALGCQVYEGYGQTECTAGCTFTTPGDWT 501

  Fly   484 PNHVGPPVSCNAVKLVDVPEMEYFANQNTGEVCVRGSNVFHGYYKDPEKTAEAIDSEGWHHTGDV 548
            ..|||.|:.||.:|||||.|:.|:|.:..||:||||.|||.||.|||::|.||:||:||.||||:
Human   502 SGHVGAPLPCNHIKLVDVEELNYWACKGEGEICVRGPNVFKGYLKDPDRTKEALDSDGWLHTGDI 566

  Fly   549 GMWLPNGTLRIIDRRKHIFKLSQGEYIVPEKIENIYTLSQYVNQVYVYGESLKSCIIAVVVPDTD 613
            |.|||.|||:||||:||||||:||||:.||||||||..||.|.|:||:|:|||:.::.:||||.:
Human   567 GKWLPAGTLKIIDRKKHIFKLAQGEYVAPEKIENIYIRSQPVAQIYVHGDSLKAFLVGIVVPDPE 631

  Fly   614 VLKQWATENNVRGTLSVLCNNKNVKELIMNDMLNWGKQSGLKSFEQVKDIYLHPDPFSVQNGLLT 678
            |:..||.:..:.||.:.||.||::|:.|:.||:..||:|||.||||||.|::|.|.|||||||||
Human   632 VMPSWAQKRGIEGTYADLCTNKDLKKAILEDMVRLGKESGLHSFEQVKAIHIHSDMFSVQNGLLT 696

  Fly   679 PTFKAKRPQLKSYFKPQLEDMY 700
            ||.|||||:|:.|||.|:|::|
Human   697 PTLKAKRPELREYFKKQIEELY 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3961	NP_649067.2	LC-FACS_euk	130..701	CDD:341250	306/579 (53%)
ACSL6	NP_001009185.1	PLN02736	97..719	CDD:178337	323/625 (52%)
		LC-FACS_euk	141..718	CDD:213293	305/578 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	463	1.000	Domainoid score	I476
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	674	1.000	Inparanoid score	I730
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53493
OrthoDB	1	1.010	-	-		D331165at33208
OrthoFinder	1	1.000	-	-		FOG0000532
OrthoInspector	1	1.000	-	-		otm41114
orthoMCL	1	0.900	-	-		OOG6_100152
Panther	1	1.100	-	-	O	PTHR43272
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2176
SonicParanoid	1	1.000	-	-		X329
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	12	12.010