Protein Alignment CG3961 and acs-15

DIOPT Version :10

• Sequence 1: NP_649067.2
• Gene: CG3961 / 40056
• FlyBaseID: FBgn0036821
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_493856.3
• Gene: acs-15 / 187666
• WormBaseID: WBGene00019920
• Length: 703
• Species: Caenorhabditis elegans
• Alignment Length: 686
• Identity: 237/686 - (34%)
• Similarity: 361/686 - (52%)
• Gaps: 42/686 - (6%)

  Fly    40 LTLGSLAA-SVAYYFATRPVPERPLVPLENQSPLLEGPEQIHVSKFYKESKNGKFVSYITENVRT 103
            |..||||| ...::|..|   ..|...|:|||.:.....:.......|..::..|:..:|
 Worm    23 LKTGSLAAQDRGFFFGKR---REPRCDLKNQSIVQADGSRKSAWLGDKPLRHESFIGILT----- 79

  Fly   104 LYQTFREGAYAS-NNGPCLGWRETLTS--------PYQWINYDEALLRAKNFGAGMLALGAR--P 157
                    .||. ..||.:|.:|.|..        .::||.|::|...:.|....:..||..  .
 Worm    80 --------TYAGIRRGPTVGGKEMLGKRVMKNGKLEWEWITYEQAFEISDNVSQAIRKLGIEIGD 136

  Fly   158 KQLIGIYSQNRPEWILYEQGCYSFSLVVVPLYDTLGPDACAFIIRQTDMQVVIVEDDGKAAMLLE 222
            |..|||||:|||||:|.:...::||.|.||:||.:..:...:|....::.::.|:.:.|...|::
 Worm   137 KSNIGIYSKNRPEWVLSDMAIHNFSNVSVPIYDNIPNEDMHYITNLCEIPLMFVDSEDKTTQLIK 201

  Fly   223 K---APRSLKIIVAIKPIRQTTLERARSRGIQIFSFIDVEKLGAKGNH-PEVPPTAEDLCTVCYT 283
            .   ..:|||.||....:.......|.|...|::||.:..:||.|..| |..|||.|.|.|:.:|
 Worm   202 DKTYLSKSLKYIVQFDKVSDEMKAMAESNNFQLWSFDEFVELGKKHEHRPHAPPTPETLATISFT 266

  Fly   284 SGTTGNPKGVMLTHGNVVAGVCS--VILQMGDHRIRAGDVMVSFLPLAHMFERCCENGMYYVGGC 346
            |||||.|||.||||.|    :||  |..:..:|.....|..:|:|||||::||.|....:.:|..
 Worm   267 SGTTGRPKGAMLTHLN----LCSTTVACEEFEHVEGELDSYLSYLPLAHVYERHCTLAHFKIGSR 327

  Fly   347 VGFYSGDIKELTNDLKMLKPTVMPAVPRLLNRVYDKIQNDISASGLKRGLFNMAMRAKEKEI-AR 410
            :||..||...|..|::.|.|.....|||:|.::|..:.:.:....:|:.:.|.|:..|.... ..
 Worm   328 IGFSRGDPALLVEDIQALAPRTFACVPRVLGKIYKSVMSQVQDKPVKKMILNSAIAYKLYHYKMT 392

  Fly   411 GVLRRNGCWDKLVFKKVHQAFGGNLRLMVVGSAPLAGNVLTFMRCALGCLVLEGYGQTECTGAIT 475
            |...|:...||.:..|:....|.|::..::.:|....:.:.|.|.|.|..:||.||.||.:|..|
 Worm   393 GKATRDTLVDKYILHKIQMILGPNIKQFLIPAAKTDNSSMRFARGAFGIEILELYGLTETSGPTT 457

  Fly   476 LTVQGDHVPNHVGPPVSCNAVKLVDVPEMEYFANQNTGEVCVRGSNVFHGYYKDPEKTAEAIDSE 540
            :.:.||.: ..||||:||.::||||:.|:.||.::|.|||.|:|.||..||||||:.||.|...:
 Worm   458 IQLVGDML-GSVGPPISCTSIKLVDIAELGYFVDENGGEVLVKGHNVTSGYYKDPKATASAFTED 521

  Fly   541 GWHHTGDVGMWLPNGTLRIIDRRKHIFKLSQGEYIVPEKIENIYTLSQYVNQVYVYGESLKSCII 605
            |:..|||:|.:.|.|||::||||.::.||.|||::.|:..|::|..|::|.|:.|:|...|..::
 Worm   522 GFMKTGDIGKFTPEGTLQLIDRRDNVLKLPQGEFVAPDLTESLYISSKFVQQICVHGNKEKPWLV 586

  Fly   606 AVVVPDTDVLKQWAT-ENNVRG-TLSVLCNNKNVKELIMNDMLNWGKQSGLKSFEQVKDIYLHPD 668
            ||||||.:.|...|. |:|:.| |...||....:.|.::.|.::..|:......|.|..|:|.|.
 Worm   587 AVVVPDPEYLASHANLEHNIEGKTYEELCKIPALAEDVLRDFVDLTKEHNRPRHEGVFAIHLTPI 651

  Fly   669 PFSVQNGLLTPTFKAKRPQLKSYFKPQLEDMYKHLD 704
            .||.||||.|||.|.||..:..:||.|:.:|:..::
 Worm   652 AFSPQNGLTTPTHKNKRTAIAQFFKKQIVEMFDRIE 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3961	NP_649067.2	LC-FACS_euk	130..701	CDD:341250	214/581 (37%)
acs-15	NP_493856.3	Adenylate forming domain, Class I superfamily	107..683	CDD:473059	213/580 (37%)