DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3961 and acs-17

DIOPT Version :9

Sequence 1:	NP_649067.2	Gene:	CG3961 / 40056	FlyBaseID:	FBgn0036821	Length:	704	Species:	Drosophila melanogaster
Sequence 2:	NP_001360705.1	Gene:	acs-17 / 180859	WormBaseID:	WBGene00016716	Length:	721	Species:	Caenorhabditis elegans

Alignment Length:	734	Identity:	204/734 - (27%)
Similarity:	346/734 - (47%)	Gaps:	102/734 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 TLTLGSLAASVAYY------FATRPVPERPLVPLENQSPLLEGPEQIHVSKFYK--ESKNGKFVS 95
            |:||..:...:.::      |....:...|...||....:...|:....:..:|  .:|:|...|
Worm    19 TITLAIVLLKIVFFIYDVVTFIPFKIFADPAEKLEKSERVKAEPDNGDPTTPWKNVSAKDGLMNS 83

  Fly    96 YITENVRTLYQTFREGAYASNNGPCLGWRETL-----------------TSPYQWINYDEALLRA 143
            .. |.:..|...:.|......|.||:|.||.|                 ...|.|.:|.:...|.
Worm    84 SF-EGIHDLGTQWEECVRRYGNQPCMGTREVLKVHKEKQSNGKIFEKWQMGDYHWRSYAQVDKRV 147

  Fly   144 KNFGAGMLALGARPKQLIGIYSQNRPEWILYEQGCYSFSLVVVPLYDTLGPDACAFIIRQTDMQV 208
            ....:|:.:||.:.|:.|.::::.|.||:.....|...:..:..:|.|||.:|..|.|.:...:.
Worm   148 NMIASGLTSLGQQEKEPIILFAETREEWMTTALACMKMNFPIATMYATLGDEAVQFAINEVGAKT 212

  Fly   209 VIVEDD--GKAAMLLEKAPRSLKIIV---AIKPIRQTTLERARSRGIQI-----FSFIDVEKLGA 263
            :...:.  .|....:.....|::.|:   ::.|         .|||..:     |:.:..::|.:
Worm   213 IFTSEALISKVKKAMSNGATSIENIIFFDSVDP---------ASRGESVDVDLPFTLLSFDQLLS 268

  Fly   264 KG----NHPEVPPTA--EDLCTVCYTSGTTGNPKGVMLTHGNVVAGVCSVILQMGDHRIRAG--- 319
            :|    ::| ||..:  :||..:.|||||||||||||::|.|:||             :.||
Worm   269 RGEREYSYP-VPTRSKKDDLAFIMYTSGTTGNPKGVMISHQNIVA-------------VTAGQAF 319

  Fly   320 -------DVMVSFLPLAHMFERCCENGMYYVGGCVGFYSGD---------IKELTNDLKMLKPTV 368
                   |..:.:|||||:.|.|.|..::..|..:|:.|..         :|....|..:|:||:
Worm   320 NIVLGPDDRYIGYLPLAHILEVCAEMVVFTKGVRIGYSSAQTLFDRAPKIMKGEHGDCWVLQPTL 384

  Fly   369 MPAVPRLLNRVYDKIQNDISA-SGLKRGLFNMAMRAKEKEIARG----VLRRNGCWDKLVFKKVH 428
            |..||.:::|::..:.::::| |.|.:.||......|......|    :|      :||||.::.
Worm   385 MACVPAVMDRIFKAVIDEVNANSELFKQLFKTCYERKRSRYEEGYTSFIL------NKLVFNRIG 443

  Fly   429 QAFGGNLRLMVVGSAPLAGNVLTFMRCALGCLVLEGYGQTECTGAITLTVQGDHVPNHVGPPVSC 493
            :..||.:|.::.|.|||:.....||.....|.|::|||.||..|..|:....|.....||||::|
Worm   444 KLLGGKVRQILSGGAPLSPETQRFMNICFCCPVVQGYGLTETCGGGTIADIHDLSTGTVGPPLTC 508

  Fly   494 NAVKLVDVPEMEYFANQN--TGEVCVRGSNVFHGYYKDPEKTAE---AIDSEGWHHTGDVGMWLP 553
            ..:.|.:..|..|....:  .||:.:.|.||..||:|:.|||.|   .::.:.:..|||:|.:..
Worm   509 CEILLQEWAEAGYSPKNDPPQGEILISGPNVALGYFKNDEKTKEEFVKVNGKTFFATGDIGEFRE 573

  Fly   554 NGTLRIIDRRKHIFKLSQGEYIVPEKIENIYTLSQYVNQVYVYGESLKSCIIAVVVPDTDVLKQW 618
            :|:|:||||:|.:.||:.||||...|:|.....:..|:.|.|||:|.||.::|:|||:...|.|.
Worm   574 DGSLKIIDRKKDLLKLAHGEYISLGKVETNLLTNPNVDNVCVYGDSNKSFLVALVVPNQKNLTQL 638

  Fly   619 ATENNV-RGTLSVLCNNKNVKELIMNDMLNWGKQSGLKSFEQVKDIYLHPDPFSVQNGLLTPTFK 682
            |::... ......||.:|.|.|.:..::..:| .|.|:..|..:.|::..:|::..:||||...|
Worm   639 ASKAGASNDNFEKLCEDKKVVEALQKELAQYG-ASKLQRVEIPQKIFICHEPWTPASGLLTEALK 702

  Fly   683 AKRPQLKSYFKPQLEDMYK 701
            .||..::..|:.:|:::||
Worm   703 LKRKNIEKAFRKELDELYK 721

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3961	NP_649067.2	LC-FACS_euk	130..701	CDD:341250	180/616 (29%)
acs-17	NP_001360705.1	LC_FACS_euk1	133..708	CDD:341294	178/604 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53493
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820