Protein Alignment CG3961 and acs-13

DIOPT Version :9

• Sequence 1: NP_649067.2
• Gene: CG3961 / 40056
• FlyBaseID: FBgn0036821
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_001293196.1
• Gene: acs-13 / 171643
• WormBaseID: WBGene00022037
• Length: 726
• Species: Caenorhabditis elegans
• Alignment Length: 688
• Identity: 336/688 - (48%)
• Similarity: 460/688 - (66%)
• Gaps: 26/688 - (3%)

  Fly    28 GYLYYLGGTLGTLTLGSLAASVAYYFATRPVPERPLVPLENQSPLLEGPEQIHVSKFYKESKNGK 92
            |..|||..: .:.|.||.:.|...|...    .:|||...|||.:|  |:...:|.:.|:.   :
 Worm    52 GLGYYLSKS-SSSTSGSYSFSGVTYSGN----VKPLVDPMNQSRIL--PDGSRISAYLKDD---E 106

  Fly    93 FVSYITENVRTLYQTFREGAYASNNGPCLGWRETLTS---PYQWINYDEALLRAKNFGAGMLALG 154
            ..:::.|:.|||||..|.||..|||||.||.|...:.   ||.|.:|:..|.||.|.......||
 Worm   107 LQAFLFEDARTLYQGVRRGARLSNNGPMLGRRVKQSDGSIPYVWESYNTILERADNVSVAFRELG 171

  Fly   155 ARP--KQLIGIYSQNRPEWILYEQGCYSFSLVVVPLYDTLGPDACAFIIRQTDMQVVIVEDDGKA 217
            ...  .:.|||||:||.|||:.|...|::|.|:||:|:|||.:|..||:.|.::::|:.:|..||
 Worm   172 VPTGNAENIGIYSKNRAEWIITEFATYNYSNVIVPIYETLGSEASIFILNQAEIKIVVCDDISKA 236

  Fly   218 AMLL---EKAPRSLKIIVAIKPIRQTTLERARSRGIQIFSFIDVEKLG--AKGNHPEVPPTAEDL 277
            ..||   |:.| ||..:|.::|:.......|.|.|:::.:|.|:||:|  ||.....:|||.|||
 Worm   237 TGLLKFKEQCP-SLSTLVVMEPVTDELKTTASSLGVEVLTFEDLEKIGKNAKTRPAHIPPTPEDL 300

  Fly   278 CTVCYTSGTTGNPKGVMLTHGNVVA-GVCSVILQMGDHR-IRAGDVMVSFLPLAHMFERCCENGM 340
            .|:||||||||.||||||||.||:| |||   :....|. |.|.|.|:||||||||.||..|:..
 Worm   301 ATICYTSGTTGTPKGVMLTHANVIADGVC---MDFFKHSGIAATDSMISFLPLAHMLERVIESVC 362

  Fly   341 YYVGGCVGFYSGDIKELTNDLKMLKPTVMPAVPRLLNRVYDKIQNDISASGLKRGLFNMAMRAKE 405
            :.||..||||.|||:.|..|:|.|||||:|.|||:|||:|||:.::::.|.||:.||:.|:..|.
 Worm   363 FCVGAKVGFYRGDIRVLAEDIKELKPTVVPVVPRVLNRLYDKVMSEVNKSTLKKMLFDFAISYKA 427

  Fly   406 KEIARGVLRRNGCWDKLVFKKVHQAFGGNLRLMVVGSAPLAGNVLTFMRCALGCLVLEGYGQTEC 470
            :::|...:|.:|.:|.|||||:.:.|||.:|||:.|||||:.|||||:|.|:||:|:||||||||
 Worm   428 RDMANFNIRNDGFFDNLVFKKIREGFGGRVRLMITGSAPLSTNVLTFVRAAMGCVVVEGYGQTEC 492

  Fly   471 TGAITLTVQGDHVPNHVGPPVSCNAVKLVDVPEMEYFANQNTGEVCVRGSNVFHGYYKDPEKTAE 535
            ..|.|::::||.:..|||..:....:|||||||:.|:|....|||||:|..:|.||||:.::|.|
 Worm   493 VAACTVSMEGDSLAGHVGMVIPSCQIKLVDVPELNYYAKDQAGEVCVKGHIIFKGYYKNEQQTKE 557

  Fly   536 AIDSEGWHHTGDVGMWLPNGTLRIIDRRKHIFKLSQGEYIVPEKIENIYTLSQYVNQVYVYGESL 600
            .||.:||.||||:|.|.|.|||:|:||:|||||||||||:.||||||||..|:||.|.:|:||||
 Worm   558 TIDEDGWLHTGDIGRWTPEGTLKIVDRKKHIFKLSQGEYVAPEKIENIYVRSKYVAQSFVHGESL 622

  Fly   601 KSCIIAVVVPDTDVLKQWATENNVRGTLSVLCNNKNVKELIMNDMLNWGKQSGLKSFEQVKDIYL 665
            |:|:||:||||.:||.....:..::||...||||..||:.|::||:..||::||.|||||:||.|
 Worm   623 KTCLIAIVVPDAEVLVPAMADQGIKGTFEELCNNDAVKKAILDDMVAVGKKAGLFSFEQVRDISL 687

  Fly   666 HPDPFSVQNGLLTPTFKAKRPQLKSYFKPQLEDMYKHL 703
            ..:.|||:|.|||||.|:|||:||:::..||:.||..|
 Worm   688 SAEQFSVENDLLTPTLKSKRPKLKAHYSKQLDAMYSKL 725

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3961	NP_649067.2	LC-FACS_euk	130..701	CDD:341250	298/579 (51%)
acs-13	NP_001293196.1	LC-FACS_euk	147..723	CDD:341250	298/579 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162552
Domainoid	1	1.000	449	1.000	Domainoid score	I269
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H69208
Inparanoid	1	1.050	637	1.000	Inparanoid score	I454
Isobase	1	0.950	-	0	Normalized mean entropy	S1301
OMA	1	1.010	-	-		QHG53493
OrthoDB	1	1.010	-	-		D331165at33208
OrthoFinder	1	1.000	-	-		FOG0000532
OrthoInspector	1	1.000	-	-		oto18367
orthoMCL	1	0.900	-	-		OOG6_100152
Panther	1	1.100	-	-	LDO	PTHR43272
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2176
SonicParanoid	1	1.000	-	-		X329
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750