DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3961 and Acsbg1

DIOPT Version :9

Sequence 1:	NP_649067.2	Gene:	CG3961 / 40056	FlyBaseID:	FBgn0036821	Length:	704	Species:	Drosophila melanogaster
Sequence 2:	NP_599216.1	Gene:	Acsbg1 / 171410	RGDID:	708557	Length:	721	Species:	Rattus norvegicus

Alignment Length:	755	Identity:	193/755 - (25%)
Similarity:	303/755 - (40%)	Gaps:	152/755 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 GGTLGTLTLGSLAASVAYYFATRPVPERPLVPLENQSPL----LEGPEQIHVSK-------FYKE 87
            |.::||....|..:|:        :..|   .|..:||.    |..||:...:.       .:..
  Rat    28 GASMGTSPDNSQTSSL--------IDGR---TLSKESPSHGLELSAPEKARAASLDASEEALWTT 81

  Fly    88 SKNG----KFVSYITENVRTLYQTFREGAYASNNGPCLGWRETLTSPYQWINYDEALLRAKNFGA 148
            ..:|    :...:.|:...|::|.|.|......|...||::.  ...::.|:|.:..|.|:....
  Rat    82 RADGRVRLRLEPFCTQLPYTVHQMFYEALDKYGNLSALGFKR--KDKWERISYYQYYLIARKVAK 144

  Fly   149 GMLALGARPKQLIGIYSQNRPEWILYEQGCYSFSLVVVPLYDTLGPDACAFIIRQTDMQVVIVED 213
            |.|.||......:.|...|.|||.....|......:|..:|.|..|:||.:|.......|::|:.
  Rat   145 GFLKLGLERAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAHDCRANVIVVDT 209

  Fly   214 DGKAAMLLE--KAPRSLKIIVAIKPIRQTTLERARSRGIQIFSFIDVEKLGAKGNHPEVPPTAED 276
            ..:...:|:  |....||.:|..:       |....:...:::..::.:||     .|||..|.|
  Rat   210 QKQLEKILKIWKDLPHLKAVVIYQ-------EPPPKKMANVYTMEELIELG-----QEVPEEALD 262

  Fly   277 ----------LCTVCYTSGTTGNPKGVMLTHGNVVAGVCSVILQMGDHRIRAGD---------VM 322
                      .|.:.||||||||||||||:..|        |.....:..:|||         |:
  Rat   263 AIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDN--------ITWTARYGSQAGDIQPAEVQQEVV 319

  Fly   323 VSFLPLAHMFERCCE--NGMYYVGGCVGFYSGDIKE--LTNDLKMLKPTVMPAVPRLLNRVYDKI 383
            ||:|||:|:..:..:  .|:.: |..|.|...|..:  |.|.|:.::||....|||:..::.::|
  Rat   320 VSYLPLSHIAAQIYDLWTGIQW-GAQVCFADPDALKGTLVNTLREVEPTSHMGVPRVWEKIMERI 383

  Fly   384 QNDISASG-LKRGLFNMAMRAKEKEIARGVLRRN-GC------------WDKLVFKKVHQAFG-G 433
            |...:.|| ::|.:...||..        .|.:| .|            .|.||..:|.||.| .
  Rat   384 QEVAAQSGFIRRKMLLWAMSV--------TLEQNLTCPSNDLKPFTSRLADYLVLARVRQALGFA 440

  Fly   434 NLRLMVVGSAPLAGNVLTFMRCALGCLVLEGYGQTECTGAITLTVQGDHVPNHVGPPVS------ 492
            ..:....|:||:......|. ..|...:..|||.:|.||           |:.:..|.:
  Rat   441 KCQKNFYGAAPMTAETQRFF-LGLNIRLYAGYGLSESTG-----------PHFMSSPYNYRLYSS 493

  Fly   493 ------CNAVKLVDVPEMEYFANQNT---GEVCVRGSNVFHGYYKDPEKTAEAIDSEGWHHTGDV 548
                  |. ||||         ||:.   ||:|:.|..:|.||....:||.||||||||.||||:
  Rat   494 GRVVPGCR-VKLV---------NQDADGIGEICLWGRTIFMGYLNMEDKTHEAIDSEGWLHTGDM 548

  Fly   549 GMWLPNGTLRIIDRRKHIFKLSQGEYIVPEKIENIYTLS-QYVNQVYVYGE---------SLKSC 603
            |....:|.|.|..|.|.:...:.||.:.|..||....:. ..::...:.|:         :||..
  Rat   549 GRLDDDGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISSAMLIGDQRKFLSMLLTLKCT 613

  Fly   604 IIAVVVPDTDVLKQWATE-----NNVRGTLSVLCNNKN--VKELIMNDMLNWGKQSGLKSFEQVK 661
            :.......||.|.:.|.|     .:...|:|.:...|:  |.:.|...:......:..:.:...|
  Rat   614 LNPETSEPTDNLTEQAVEFCQRVGSKASTVSEIVGQKDEAVYQAIHEGIQRVNANAAARPYHIQK 678

  Fly   662 DIYLHPDPFSVQNGLLTPTFKAKRPQLKSYFKPQLEDMYK 701
            ...|..| ||:..|.|.||.|.||..:...:|..::..|:
  Rat   679 WAILERD-FSISGGELGPTMKLKRLTVLEKYKDIIDSFYQ 717

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3961	NP_649067.2	LC-FACS_euk	130..701	CDD:341250	171/642 (27%)
Acsbg1	NP_599216.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..64		10/46 (22%)
Acsbg1	NP_599216.1	ACSBG_like	122..716	CDD:341256	171/647 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810