Protein Alignment CG3961 and Acsl3

DIOPT Version :10

• Sequence 1: NP_649067.2
• Gene: CG3961 / 40056
• FlyBaseID: FBgn0036821
• Length: 704
• Species: Drosophila melanogaster
• Sequence 2: NP_476448.1
• Gene: Acsl3 / 114024
• RGDID: 70552
• Length: 720
• Species: Rattus norvegicus
• Alignment Length: 759
• Identity: 229/759 - (30%)
• Similarity: 364/759 - (47%)
• Gaps: 109/759 - (14%)

  Fly     2 TPEKSVMAYVNHLIVSNFSYFWDEIDGYLYYLGGTLGTLTLGSLAASVAYYFATRPVPERPLVPL 66
            ||....:....|.|:..|.:|                .::|.::...:.:||......|:|
  Rat     8 TPSTMKLKQTIHPILLYFIHF----------------IISLYTILTYIPFYFLCESKQEKP---- 52

  Fly    67 ENQ---SPLLEGPEQIHVSKFYKESKNGKFVSYITENVRTLYQTFREGAYASN---NGPCLGWRE 125
             |.   .|:...|:..:.|   ..|.:| ..|.:.....||.:.|   .||.|   :...||.||
  Rat    53 -NHIKAKPVSSKPDSAYRS---VNSMDG-LASVLYPGCDTLDKVF---MYAKNKFKDKRLLGTRE 109

  Fly   126 TLTSP-----------------YQWINYDEALLRAKNFGAGMLALGARPKQLIGIYSQNRPEWIL 173
            .|...                 |.|::|::..:||.:||.|:..||.:||..|.|:.:.|.||::
  Rat   110 ILNEEDEIQPNGKVFKKVILGHYNWLSYEDVFIRALDFGNGLQMLGQKPKANIAIFCETRAEWMI 174

  Fly   174 YEQGCYSFSLVVVPLYDTLGPDACAFIIRQTDMQVVIVEDD---GKAAMLLEKAPRSLKIIVAI- 234
            ..|.|:.::..:|.||.|||..|....:.:|::..:|...:   .|...::...|| |:.|:.:
  Rat   175 AAQACFMYNFQLVTLYATLGGPAIVHGLNETEVTNIITSKELLQTKLKDIVSLVPR-LRHIITVD 238

  Fly   235 -KPIRQTTLERARSRGIQIFSFIDVEKLGAKGN-----HPEVPPTAEDLCTVCYTSGTTGNPKGV 293
             ||...:..    .:|:.:.:...|:.||.|.:     |.:  |...|:..:.||||:||.||||
  Rat   239 GKPPTWSEF----PKGVIVHTMAAVQALGVKADVDKKAHSK--PLPSDIAVIMYTSGSTGIPKGV 297

  Fly   294 MLTHGNVVA---GVCSVILQMGDHRIRAGDVMVSFLPLAHMFERCCENGMYYVGGCVGF------ 349
            |::|.|::|   |:...|.::|:.     ||.:.:|||||:.|...|......|..:|:
  Rat   298 MISHSNIIASITGMARRIPRLGEE-----DVYIGYLPLAHVLELSAELVCLSHGCRIGYSSPQTL 357

  Fly   350 --YSGDIKE-LTNDLKMLKPTVMPAVPRLLNRVYDKIQNDIS-ASGLKRGLFNMAMRAKEKEIAR 410
              .|..||: ...|..:||||:|.|||.:::|:|..:.|.:: .|..:|.||.:|...|.::|::
  Rat   358 ADQSSKIKKGSKGDTSVLKPTLMAAVPEIMDRIYKNVMNKVNEMSAFQRNLFILAYNYKMEQISK 422

  Fly   411 GVLRRNGC----WDKLVFKKVHQAFGGNLRLMVVGSAPLAGNVLTFMRCALGCLVLEGYGQTECT 471
                  ||    .|:.||:.|.:..|||:|:::.|.|||:.....||.....|.|.:|||.||.|
  Rat   423 ------GCSTPLCDRFVFRNVRRLLGGNIRVLLCGGAPLSATTQRFMNICFCCPVGQGYGLTEST 481

  Fly   472 GAITLTVQGDHVPNHVGPPVSCNAVKLVDVPEMEYFANQNT------GEVCVRGSNVFHGYYKDP 530
            ||.|:|...|:....||.|:.|..:||.:..|..||   ||      ||:.:.|.||..||||:.
  Rat   482 GAGTITEVWDYNTGRVGAPLVCCEIKLKNWEEGGYF---NTDKPHPRGEILIGGQNVTMGYYKNE 543

  Fly   531 EKT-AEAIDSEG---WHHTGDVGMWLPNGTLRIIDRRKHIFKLSQGEYIVPEKIENIYTLSQYVN 591
            .|| |:..:.|.   |..|||:|.:.|:|.|:||||:|.:.||..|||:...|:|........::
  Rat   544 AKTKADFFEDENGQRWLCTGDIGEFDPDGCLKIIDRKKDLVKLQAGEYVSLGKVEAALKNLPLID 608

  Fly   592 QVYVYGESLKSCIIAVVVPDTDVLKQWATENNVRGTLSVLCNNKNVKELIMNDMLNWGKQSGLKS 656
            .:..|..|..|.:|..|||:...|.:.|......||...|||:..::..::..:......:.|:.
  Rat   609 NICAYANSYHSYVIGFVVPNQKELTELARTKGFNGTWEELCNSSEMENEVLKVLSEAAISASLEK 673

  Fly   657 FEQVKDIYLHPDPFSVQNGLLTPTFKAKRPQLKSYFKPQLEDMY 700
            ||....|.|.|||::.:.||:|..||.||.:||::::..:|.||
  Rat   674 FEIPLKIRLSPDPWTPETGLVTDAFKLKRKELKTHYQADIERMY 717

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3961	NP_649067.2	LC-FACS_euk	130..701	CDD:341250	200/625 (32%)
Acsl3	NP_476448.1	Adenylate forming domain, Class I superfamily	30..717	CDD:473059	221/719 (31%)