DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3961 and acsbg1

DIOPT Version :9

Sequence 1:	NP_649067.2	Gene:	CG3961 / 40056	FlyBaseID:	FBgn0036821	Length:	704	Species:	Drosophila melanogaster
Sequence 2:	XP_001344904.2	Gene:	acsbg1 / 100006023	ZFINID:	ZDB-GENE-110914-219	Length:	674	Species:	Danio rerio

Alignment Length:	680	Identity:	182/680 - (26%)
Similarity:	276/680 - (40%)	Gaps:	144/680 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 TLYQTFREG--------AYASNNGPCLGWRETLTSPYQWINYDEALLRAKNFGAGMLALGARPKQ 159
            |::|.|...        |.||..|.  .|.:.....|    |....:.||    |.|.||.....
Zfish    57 TVHQMFYNSVQKYGNLTALASKRGN--KWEKATFLEY----YHLCRMAAK----GFLKLGLEQFH 111

  Fly   160 LIGIYSQNRPEWILYEQGCYSFSLVVVPLYDTLGPDACAFIIRQTDMQVVIVEDD---GKAAMLL 221
            .:.|...|..||.:...|......::..:|.|..||||..:...:...|::||:.   .|...:.
Zfish   112 GVAILGFNSAEWFIAAVGTVFAGGIMAGIYTTNSPDACLHVANDSRANVIVVENQKQLDKIMQVK 176

  Fly   222 EKAPRSLKIIVAIKPIRQTTLERARSRGIQIFSFIDVEKLGAKGNHPEVPPT-----AEDLCTVC 281
            :|.|. ||.||......:..|       ..::|:.:..:||.:.:..|:...     |...|.:.
Zfish   177 DKLPH-LKAIVQYSGSLKEKL-------ANLYSWEEFMELGLEVSDHELDEVISKQRANQCCVLI 233

  Fly   282 YTSGTTGNPKGVMLTHGNVVAGVCSVILQMGDHRIRAGDV---------MVSFLPLAHMFERCCE 337
            |||||||:||||||:|.|        |.....|..||||:         :||:|||:|:..:..:
Zfish   234 YTSGTTGSPKGVMLSHDN--------ITWTAHHASRAGDMQPAEIRQESLVSYLPLSHIAAQIYD 290

  Fly   338 --NGMYYVGGCVGFYSGDIKE--LTNDLKMLKPTVMPAVPRLLNRVYDKIQNDISASG-LKRGLF 397
              .|:.: |..:.|...|..:  |.:.|:.:.||....|||:..::.:||:..||..| :||.:.
Zfish   291 LWTGIKW-GEQISFAQPDALKGTLVDSLREVTPTAHMGVPRVWEKIMEKIKEGISRCGYMKRKMV 354

  Fly   398 NMAM--------RAKEKE-------IARGVLRRNGCWDKLVFKKVHQAFG-GNLRLMVVGSAPLA 446
            ..||        |.|:.|       :|          :||:.:|:....| .:......|:||:.
Zfish   355 TWAMSVSLDANQRLKKDEEKSFLFTLA----------EKLILQKLRAELGFSSCVKFFSGAAPIG 409

  Fly   447 GNVLTFMRCALGCLVLEGYGQTECTGAITLTVQGDHVPNHVGPP-----VSCNAVKLVDVPEMEY 506
            ...|.|. ..|...:.|.||.:|.:|           |:.:..|     :||..|    ||..:|
Zfish   410 RETLQFF-LGLNIRLYEAYGMSETSG-----------PHFMSGPEAYQFLSCGKV----VPGCQY 458

  Fly   507 -FANQN---TGEVCVRGSNVFHGYYKDPEKTAEAIDSEGWHHTGDVGMWLPNGTLRIIDRRKHIF 567
             ..|.|   :||||..|.|||.|:....:||.||:|.:||..:||:|....:|.:.|..|.|.:.
Zfish   459 KLININADGSGEVCFWGRNVFMGFLNLEDKTKEALDEDGWLRSGDLGKVDEDGFIYINGRIKELI 523

  Fly   568 KLSQGEYIVPEKIENI--YTLSQYVNQVYVYGE--------SLKSCIIAVVVPDTDVLKQWATEN 622
            ..:.||.|.|..||:.  ..||...|.:.:..|        :||..:.......||:|...|.|
Zfish   524 ITAGGENIPPLPIEDAVKQELSIISNAMLIGDERKFLSMLLTLKCTVNPETTEPTDILSLEAVE- 587

  Fly   623 NVRGTLSVLCNNKNVKELIMNDMLNWGKQSGLKSFE----QV------------KDIYLHPDPFS 671
                    .|.....:...::|:.....:...||.|    ||            |...|..| ||
Zfish   588 --------FCQRIGSQSTKLSDITGGKDKLVYKSIEDGIGQVNSKATSNAQRIQKWTILDKD-FS 643

  Fly   672 VQNGLLTPTFKAKRPQLKSYFKPQLEDMYK 701
            |..|.|.||.|.:||.:...:..::|:.|:
Zfish   644 VAGGELGPTMKLRRPVVLQMYHNEIENFYR 673

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3961	NP_649067.2	LC-FACS_euk	130..701	CDD:341250	173/643 (27%)
acsbg1	XP_001344904.2	FAA1	60..674	CDD:223953	181/677 (27%)
acsbg1	XP_001344904.2	ACSBG_like	78..672	CDD:213299	175/656 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1022
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810