Protein Alignment Uggt and uggt-2

DIOPT Version :9

• Sequence 1: NP_524151.2
• Gene: Uggt / 40055
• FlyBaseID: FBgn0014075
• Length: 1548
• Species: Drosophila melanogaster
• Sequence 2: NP_492484.2
• Gene: uggt-2 / 172758
• WormBaseID: WBGene00009178
• Length: 1381
• Species: Caenorhabditis elegans
• Alignment Length: 1548
• Identity: 522/1548 - (33%)
• Similarity: 797/1548 - (51%)
• Gaps: 231/1548 - (14%)

  Fly    30 ITTLINAKWTQTPLYLEIAEYLADEQAGLFWDYVSGVT-KLDTVLNEYDTESQQYNAALELVKSH 93
            |...:||||..:.:..||:||:..|....||::|:.|. ::|...|:.|:...:|:..:.:..:.
 Worm    22 INVRLNAKWRSSSILAEISEYIGKENPEAFWNFVNSVNQEIDETSNKNDSIRNKYDFGMSVANNI 86

  Fly    94 VSSPQLPLLRLVVSMHSLTPRIQTHFQLAEELRSSGSCQSFTFAQVGSELACSFNELQKKLEVPL 158
            :...::.|||..::..|::||:|.|.|:..|.:.. .| ||:|...|.:..|..:||.
 Worm    87 LGPFEMKLLRFSLATRSISPRVQAHEQIGMEFKPE-KC-SFSFFVYGGQAGCQLSELN------- 142

  Fly   159 AKDSLDASVVTYSFDHIFPGSENNTRTVVLYGDLGSSQFRTY----HKLLEKEANAGRIRYILRH 219
            ..:..|.::..:|||||:|......:|:::||:||:.:.:..    ..|:||..|   :|:::||
 Worm   143 LNNYDDNNLKIFSFDHIYPVQSTAEKTILIYGELGTYELKNLLLEAQSLIEKHKN---LRFVVRH 204

  Fly   220 QLAKKDKRPVRLSGYGVELHLKSTEYKSQDDAPKPEAGSTSDEDLANESDVQGFDFKVLKQKHPT 284
            .....|::| .||||||||.||:||||:.|        |:|...|....::.|.:||:||.:|..
 Worm   205 FSRFSDQKP-SLSGYGVELALKNTEYKAVD--------SSSTNKLDEPENLHGLNFKILKNRHLE 260

  Fly   285 LKRALDQLRQRLLQGNDEIAQLKAWEFQDLGLQAAAAIAEIQGDETLQILQYTAHNFPMLARTLL 349
            |:..|:.||:. |:...||..||.|:.:|||.:....:..:.....::||   ..:||..||...
 Worm   261 LQNELESLREN-LEKQGEIVPLKQWQLKDLGFKTCQKLKSLTEIREMEIL---LQDFPTHARVTS 321

  Fly   350 AHKVTDGLRAEV---KHNTEAFG--RSLNVAPPDGALFINGLFFDADTMDLYSLIETLRSEMRVL 409
            ...:.:.|:..:   :...||.|  ...|:...:|.:...|..|    :||::|:|.:..|.:::
 Worm   322 HQNLNETLQRSIQKGQETLEAKGIESGTNILAINGRVIAKGDSF----VDLFALMEKVEEEKKMV 382

  Fly   410 ESLHSNNVRG------------SLASSLLALDLTASSKKEFAIDIRDTAVQWVNDIENDVQYRRW 462
            ...    |:|            ::...|..:||::....|.|.|.......::||:|:    .|.
 Worm   383 NEF----VKGFGNSETEEFERINIPKMLTLVDLSSVKLSEHAFDYSIAEPVYLNDLES----TRS 439

  Fly   463 P-SSVMDLLRPTFPGMLRNIRKNVFNLVLVVDALQPTARSVIKLSESFV--IHQAPIRLGLVFDA 524
            | .|:|.:|:|..||.:|.|.:|:|||::.:|......|....:..:|.  ||   ||.|
 Worm   440 PYKSLMLMLQPFPPGQIRPISRNIFNLIMFLDPFDSDDRVFDDVIRNFQTGIH---IRFG----- 496

  Fly   525 RDANEDNLADYVAITCAYNYVSQKKDARAALSFLTDIYAAVGETKVV---TKKDIVKQLTKEFTS 586
                      :|.|.....|....::|..::        .|..||.|   :|..::..|.|
 Worm   497 ----------FVPILDEAKYGKSIEEAVDSM--------IVPPTKKVFWKSKDSLINALKK---- 539

  Fly   587 LSFAKAEEFLEEDSTYDYGRELAAEFIQRLGFGDKGQPQALLNGVPMPSNVVTADSDFEEAIFTE 651
                                  .:.|:...|...  .|..||||.|:.   ||:...||.::...
 Worm   540 ----------------------GSRFVAEAGLTQ--LPLVLLNGYPLD---VTSIERFESSLTQN 577

  Fly   652 IMTHTSNLQKAVYKGELTDNDVAID----YLMNQPHVMPRLNQRILSQEDVKYLDINGVAYKNLG 712
            |...|:.||.|:..| |.::.|.||    .....|.::.||||||.:            |:.|..
 Worm   578 IQKQTTRLQLALLHG-LIEDSVQIDRWWFEKKTNPDIIQRLNQRITT------------AFNNKE 629

  Fly   713 NVGVLNRLSNRDMTATLMDNLKYFGGKKSTELIGRASLQFLTIWVFADLETDQGRDLLTHALDYV 777
            .:.:..|      :...:.|:.||..:..|.|....    :|.|:.||.|....|...|.|:..:
 Worm   630 FLNISRR------SIQFLKNVHYFSEESDTVLANAD----VTTWIIADFENPSNRLFATKAIRSI 684

  Fly   778 QSGESVRVAFIPNTESSSASSRRNLNRLVWAAMQSLPPTQATEQVLKWLKKPKEKIEIPTQLEDI 842
            .|.::.::|.|||    .:|||.|.|          |.:...|.|     .|...:.|.:::|..
 Worm   685 ASQKNNKIALIPN----PSSSRSNDN----------PCSFNFENV-----GPNSDMTILSKIESF 730

  Fly   843 LGSTELHLKMLRVYSQRVLGLNKSQRLVIGNGRLYGPLSS-DESFDSADFALLARFSSLQYSDKV 906
            .      :|.:.: |...:|:|..:.:|:.||.|.|||:. .|...:.||..|..|...:.:.|
 Worm   731 C------MKNINL-SPLDIGVNPGETVVVSNGLLIGPLAGRTELLKTDDFNYLDTFWKEKGATK- 787

  Fly   907 RQVLKESAQDVNEEFNSDTLLKLYASLLPRQTKTRFKLPTD--LKTDH-SVVKLPPKQENLPHFD 968
                  :|...||....|..:..|.|:..:..:.:.::..|  :::.: :.:..||.........
 Worm   788 ------AATFFNENTVYDVTISFYCSIAKKFKEDQQRMDFDEFMESGNGNTIIFPPIDSTNSTIT 846

  Fly   969 VAAVLDPASRAAQKLTPILILLRQVLNCQLNLYLIPVPQHSDMPVKNFYRYVVEPEVQFEANGGR 1033
            |..:.:|.||.||::..::.:|:::.|.::.:...|.....:||:|.|||:|...::.|..:|..
 Worm   847 VTWIANPVSREAQQIISVVKILQRITNSRIEIIFNPSADIQEMPIKRFYRFVANEKLLFNEDGSM 911

  Fly  1034 SDGPLAKFSGLPANPLLTQQLQVPENWLVEAVRAVYDLDNIKLTDIGGPVHSEFDLEYLLLEGHC 1098
            .:..:. ||.||...|||..|:..:.|::|..:|.||||||.|......|.:.:.||::|:|| .
 Worm   912 ENHSVV-FSNLPQKQLLTMSLETNDAWMIEVKKAEYDLDNILLETASEDVEAVYSLEHILVEG-T 974

  Fly  1099 FDAASGAPPRGLQLVLGTQSQPTLVDTIVMANLGYFQLKANPGAWSLRLREGKSADIYAISHIEG 1163
            ....||....||::.|.:..:.  .|||||.|||||||||.||.|:|.||.|.|||.:.|..|:.
 Worm   975 SRKMSGEASDGLEVELSSGGKN--YDTIVMLNLGYFQLKAEPGVWNLHLRNGHSADEHKIVTIDS 1037

  Fly  1164 TNTHHSAGSSEVQVLITSLRSHVVKLRVSKKPGMQQAELLSDDNEQAAQSGMWNSIASSFGGGSA 1228
            ...     .:::|:::.|.....|:|.|.     :..|....|:|.:.:| :.||        :.
 Worm  1038 IPV-----ENDIQIVVDSFSGKWVELSVE-----ELTEPKESDDELSIES-LLNS--------AK 1083

  Fly  1229 NQAATDEDTETINIFSVASGHLYERLLRIMMVSLLKHTKS-PVKFWFLKNYLSPQFTDFLPHMAS 1292
            |..|:.|.:|.||:||:||||||||.:||||.|:|.:||: .||||.|||||||:|.:.:|.:|.
 Worm  1084 NYFASPEPSEVINVFSLASGHLYERFMRIMMTSVLNNTKTQKVKFWLLKNYLSPKFKETIPKLAE 1148

  Fly  1293 EYNFQYELVQYKWPRWLHQQTEKQRTIWGYKILFLDVLFPLNVRKIIFVDADAIVRTDIKELYDM 1357
            .|.|::|||:||||:|||:||||||.:||||||||||||||||.||||||||.:||.|::||.|.
 Worm  1149 FYKFEFELVEYKWPKWLHKQTEKQRVMWGYKILFLDVLFPLNVDKIIFVDADQVVRADLQELMDF 1213

  Fly  1358 DLGGAPYAYTPFCDSRKEMEGFRFWKQGYWRSHLMGRRYHISALYVVDLKRFRKIAAGDRLRGQY 1422
            :|.||||.|.|||:||.||:||||||.|||::|||||:||||||||||||.||:.:|||||||:|
 Worm  1214 NLNGAPYGYVPFCESRTEMDGFRFWKSGYWKNHLMGRKYHISALYVVDLKAFREFSAGDRLRGRY 1278

  Fly  1423 QALSQDPNSLSNLDQDLPNNMIHQVAIKSLPDDWLWCQTWCSDSNFKTAKVIDLCNNPQTKEAKL 1487
            .:||.||||||||||||||||:|:|.|||||.:||||:|||.|.:.:.||.|||||||.|||.||
 Worm  1279 DSLSADPNSLSNLDQDLPNNMLHEVPIKSLPQEWLWCETWCDDGSKEKAKTIDLCNNPLTKEPKL 1343

  Fly  1488 TAAQRIVPEWKDYDAELKTLMSRIEDHENSHSRDSAVDDSVDDSVEVTTVTPS 1540
            .:|:||:.||.:||:|:..::                     :|.::.|.:||
 Worm  1344 NSAKRIIKEWTEYDSEISKVL---------------------NSADINTPSPS 1375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uggt	NP_524151.2	UDP-g_GGTase	29..1196	CDD:283964	322/1201 (27%)
		RfaJ	1238..>1456	CDD:224359	157/218 (72%)
		GT8_HUGT1_C_like	1240..1487	CDD:133054	176/247 (71%)
uggt-2	NP_492484.2	UDP-g_GGTase	21..1060	CDD:283964	321/1196 (27%)
		GT8_HUGT1_C_like	1095..1343	CDD:133054	176/247 (71%)
		RfaJ	1112..>1302	CDD:224359	136/189 (72%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167583
Domainoid	1	1.000	436	1.000	Domainoid score	I284
eggNOG	1	0.900	-	-		E1_KOG1879
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55769
OrthoDB	1	1.010	-	-		D231263at2759
OrthoFinder	1	1.000	-	-		FOG0002023
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101176
Panther	1	1.100	-	-	O	PTHR11226
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2174
SonicParanoid	1	1.000	-	-		X1498
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.750