Protein Alignment Uggt and uggt2

DIOPT Version :9

• Sequence 1: NP_524151.2
• Gene: Uggt / 40055
• FlyBaseID: FBgn0014075
• Length: 1548
• Species: Drosophila melanogaster
• Sequence 2: XP_002942882.2
• Gene: uggt2 / 100493790
• XenbaseID: XB-GENE-997034
• Length: 1517
• Species: Xenopus tropicalis
• Alignment Length: 1585
• Identity: 677/1585 - (42%)
• Similarity: 951/1585 - (60%)
• Gaps: 105/1585 - (6%)

  Fly     1 MLRAVALCVSVVLIA---LYTPTSGESSQSYPITTLINAKWTQTPLYLEIAEYLADEQAGLFWDY 62
            ||..:.||...:.:|   ...||.|       :|..:.|||..:|..||.:|::|:|....||.:
 Frog     1 MLSPLILCFFSLTLASALAQVPTKG-------VTASLAAKWPASPFLLEASEFIAEEGNDKFWQF 58

  Fly    63 VSGVTKLDTVLNEYDTESQQYNAALELVKSHVSSPQLPLLRLVVSMHSLTPRIQTHFQLAEELRS 127
            ::.|.:| |:....|||...|:..|:.....:|..|:.||:...|:.:.:|.:|...|:|.:...
 Frog    59 LATVQEL-TIYKNKDTEYSYYSLILKKAAQFLSDLQIALLKFAFSIRAYSPTVQMFQQIAADESP 122

  Fly   128 SGSCQSFTFAQVGSELACSFNELQKKLEVPLAKDSLDAS----VVTYSFDHIFPGSENNTRTVVL 188
            ...|.:  |..|.....|..::::|.|:        :||    ...|..|||||........|:|
 Frog   123 PEGCSA--FVAVHGMHTCKPSQIKKLLK--------EASERPRPYLYKTDHIFPTLSKTAPVVIL 177

  Fly   189 YGDLGSSQFRTYHKLLEKEANAGRIRYILRHQLAKKDKRPVRLSGYGVELHLKSTEYKSQDDAPK 253
            |.::|:.:|..:||.|.::|.:|.|.|:|||.:.....|.|:||||||||.:||||||:.||. |
 Frog   178 YAEVGTKEFAKFHKTLAEKAESGEIIYVLRHYIQHPGTRKVQLSGYGVELAIKSTEYKAMDDT-K 241

  Fly   254 PEAGSTS---DEDLANESDVQGFDFKVLKQKHPTLKRALDQLRQRLLQGNDEIAQLKAWEFQDLG 315
            .||.::|   |:.:|.|  ||||.|..|.|.:|.||..|...|:.|::...|:..||.||.|||.
 Frog   242 VEANNSSPKTDDGIAEE--VQGFYFDRLMQMYPDLKENLVDFRKHLIESTHEMVPLKVWELQDLS 304

  Fly   316 LQAAAAIAEIQGDETLQILQYTAHNFPMLARTLLAHKVTDGLRAEVKHNTEAFGRSLNVAPPDGA 380
            .|||:.|......|.|::|:.|:.|||:.||:|....:...::.|::.|.:....:..:.|.|.:
 Frog   305 FQAASKIVSTPVYEALKVLRDTSQNFPIKARSLTRIALNQEMKKEIEENQKHLSETFGIHPGDAS 369

  Fly   381 LFINGLFFDADTMDLYSLIETLRSEMRVLESLHSNNVRGSLASSLLALDLTASSKKEFAIDIRDT 445
            |:||||..|.|..:.:|::|||::|.:.|..|.:..:.....|..|.:.: .|..:.:|:|||.:
 Frog   370 LYINGLHIDLDVHNSFSILETLKNEGKTLNGLSALGINNEDLSKFLRIQV-HSGDENYALDIRHS 433

  Fly   446 AVQWVNDIENDVQYRRWPSSVMDLLRPTFPGMLRNIRKNVFNLVLVVDALQPTARSVIKLSESFV 510
            ::.|:||||.|..|..|||||.:||||.|||::|.||:|.|||||.||.:|..|...:||:|.|.
 Frog   434 SITWINDIETDHMYSPWPSSVQELLRPAFPGVIRPIRRNFFNLVLFVDPVQEYAADYVKLAELFY 498

  Fly   511 IHQAPIRLGLVFDARDANEDNLAD--YVAITCAYNYVSQKKDARAALSFLTDIYAAV--GETKVV 571
            .|..|:|:|.||......|.|..:  ..|...|:||:.::.|:..|.|.:.::|..|  |||..|
 Frog   499 RHNVPLRIGFVFVVNSDEESNTGEDAGAAFLKAFNYIVEESDSAQAFSSIINMYNKVDDGETLTV 563

  Fly   572 TKKDIVKQLTKEFTSLSFAKAEEFLEEDSTYDYGRELAAEFIQRLGFGDKGQPQALLNGVPMPSN 636
               |::|.:.|  ..|.....|:.:...|.|....:..|.|.::.|.|.  .||.|.||||..|.
 Frog   564 ---DMIKSVLK--YDLPKMDIEQVMGLHSEYSNKLKAGATFYKKSGLGP--LPQVLFNGVPFNSE 621

  Fly   637 VVTADSDFEEAIFTEIMTHTSNLQKAVYKGELTDNDVAIDYLMNQPHVMPRLNQRILSQED--VK 699
            .:..: :.|..|..:|:..|...|:||:.|.|:|...|:|:||:||.|:.|:|..||:.|.  :.
 Frog   622 EMDIE-EMETVILQKILDATGFFQRAVFMGLLSDQLDAVDFLMDQPSVVSRINPSILTSEKNYIN 685

  Fly   700 YLDINGVAYKNLGNVGVLNRLSNRDMTATLMDNLKYFGGKKSTELIGRASLQFLTIWVFADLETD 764
            ::.....|...|......:.|.::|.:|.:.:::||...:....:.|      :|||:.||.:..
 Frog   686 FISTPVAAKYTLHEFDTFSFLDSQDKSAVIAEHMKYLTKEDEDVIHG------VTIWIIADFDKP 744

  Fly   765 QGRDLLTHALDYVQSGESVRVAFIPNTESSSASSRRNLNRLVWAAMQSLPPTQATEQVLKWLKK- 828
            .||.||..||.::|.....|:..:.|...........::|.:||::.    ||.::.:||:.|:
 Frog   745 SGRQLLAKALKHMQKTSITRLGILNNPTVKMTEENTLISRALWASLL----TQKSQNMLKFFKRL 805

  Fly   829 PKE----------KIE--IPTQLEDILGSTE---LHLKMLR---VYSQRVLGLNKSQRLVIGNGR 875
            .||          ||:  |.::::|.....:   :.|.:||   :|.:.||.|...|...:.|||
 Frog   806 AKEETAEALLNGRKIKDFIVSEIDDDAFEKKYNTMGLDVLRTQELYCREVLKLLPGQMATVSNGR 870

  Fly   876 LYGPLSSDESFDSADFALLARFSSLQYSDKVRQVLKESAQDVNEEFNSDTLLKLYASLLPRQTKT 940
            |...:.:|| |...||.||.:.:....::|::.::|::....|.. .||.::|: .|||....|.
 Frog   871 LLSSIDADE-FSEEDFHLLEKITYSTSAEKIKNLVKKTTTLPNRA-ASDLVMKV-DSLLSSVPKG 932

  Fly   941 RFKLPTDL-KTDHSVVKLPPKQENLPHFDVAAVLDPASRAAQKLTPILILLRQVLNCQLNLYLIP 1004
            ..:...:| |..||:||:.|:... |.|||.|::||.||.||.::..||:|.:::|.:|.:::..
 Frog   933 ESRQDVNLIKQKHSLVKVEPEDAG-PFFDVFAIVDPLSREAQMMSHFLIVLGRLINMKLTMFMNC 996

  Fly  1005 VPQHSDMPVKNFYRYVVEPEVQFEANGGRSDGPLAKFSGLPANPLLTQQLQVPENWLVEAVRAVY 1069
            ..:.|:||:|:|||.|:||||.|..|...|.||.|||..:|.:.|||..:..||:|:||||::..
 Frog   997 KSKLSEMPLKSFYRLVLEPEVTFLRNNSLSMGPSAKFLDMPESALLTLNMITPESWIVEAVQSSC 1061

  Fly  1070 DLDNIKLTDIGGPVHSEFDLEYLLLEGHCFDAASGAPPRGLQLVLGTQSQPTLVDTIVMANLGYF 1134
            |||||.|.||.|.|.:.::||||||||||||..:|.||||||..||.::.|.:||||||||||||
 Frog  1062 DLDNIHLQDIDGIVTANYELEYLLLEGHCFDVTTGQPPRGLQFTLGMKNDPVMVDTIVMANLGYF 1126

  Fly  1135 QLKANPGAWSLRLREGKSADIYAI-SHIEGTNTHHSAGSSEVQVLITSLRSHVVKLRVSKKPGMQ 1198
            |||||||||:||||||:|.:||.| ||: ||::  .:...|:.|::.:..|.::|:.|.|||...
 Frog  1127 QLKANPGAWTLRLREGRSEEIYHIFSHM-GTDS--PSDQEEIIVVLNNFNSKIIKVHVQKKPDQI 1188

  Fly  1199 QAELLSDDNEQAAQSGMWNSIASSFGGGSANQAATDEDTETINIFSVASGHLYERLLRIMMVSLL 1263
            .|:|||.:.|:  :||:|||:.|..|.|:........|  .:|||||||||||||.|||||:|:|
 Frog  1189 HADLLSSEPEE--KSGLWNSLMSFTGAGNIEDKEKKHD--VLNIFSVASGHLYERFLRIMMLSVL 1249

  Fly  1264 KHTKSPVKFWFLKNYLSPQFTDFLPHMASEYNFQYELVQYKWPRWLHQQTEKQRTIWGYKILFLD 1328
            ::||:|||||||||||||:|.:.:|.||.:|.||||||||||||||||||||||.||||||||||
 Frog  1250 RNTKTPVKFWFLKNYLSPKFKEIIPFMAEKYGFQYELVQYKWPRWLHQQTEKQRIIWGYKILFLD 1314

  Fly  1329 VLFPLNVRKIIFVDADAIVRTDIKELYDMDLGGAPYAYTPFCDSRKEMEGFRFWKQGYWRSHLMG 1393
            |||||.|.||||||||.|||.|:|||.|.:||||||.|||||||||||:|:||||.|||.|||..
 Frog  1315 VLFPLAVDKIIFVDADQIVRADLKELRDFNLGGAPYGYTPFCDSRKEMDGYRFWKSGYWASHLGH 1379

  Fly  1394 RRYHISALYVVDLKRFRKIAAGDRLRGQYQALSQDPNSLSNLDQDLPNNMIHQVAIKSLPDDWLW 1458
            |:||||||||||||:|||||||||||||||||||||||||||||||||||||||:|||||.:|||
 Frog  1380 RKYHISALYVVDLKKFRKIAAGDRLRGQYQALSQDPNSLSNLDQDLPNNMIHQVSIKSLPQEWLW 1444

  Fly  1459 CQTWCSDSNFKTAKVIDLCNNPQTKEAKLTAAQRIVPEWKDYDAELKTLMSRIEDHENSHSRDSA 1523
            |:|||.|.:.:.||.|||||||:|||.||.||.||||||.:||.|::.|:..||:...:
 Frog  1445 CETWCDDKSKEKAKTIDLCNNPKTKEPKLKAAARIVPEWTEYDTEIRQLLKDIEEQSKN------ 1503

  Fly  1524 VDDSVDDSVEVTTVTPSHEPKHGEL 1548
                       .|.:..:..||.||
 Frog  1504 -----------ITASSGNGLKHDEL 1517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uggt	NP_524151.2	UDP-g_GGTase	29..1196	CDD:283964	434/1200 (36%)
		RfaJ	1238..>1456	CDD:224359	179/217 (82%)
		GT8_HUGT1_C_like	1240..1487	CDD:133054	199/246 (81%)
uggt2	XP_002942882.2	Thioredoxin_12	36..217	CDD:375826	54/191 (28%)
		Thioredoxin_13	287..415	CDD:375827	41/127 (32%)
		Thioredoxin_14	428..676	CDD:375828	98/255 (38%)
		Thioredoxin_15	702..927	CDD:375829	61/237 (26%)
		UDP-g_GGTase	1087..1194	CDD:368901	61/109 (56%)
		Glyco_transf_24	1226..1493	CDD:375830	212/266 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	464	1.000	Domainoid score	I467
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1233	1.000	Inparanoid score	I183
OMA	1	1.010	-	-		QHG55769
OrthoDB	1	1.010	-	-		D231263at2759
OrthoFinder	1	1.000	-	-		FOG0002023
OrthoInspector	1	1.000	-	-		otm47810
Panther	1	1.100	-	-	LDO	PTHR11226
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2174
SonicParanoid	1	1.000	-	-		X1498
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110