DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rad9 and rad9b

DIOPT Version :9

Sequence 1:	NP_001097639.2	Gene:	Rad9 / 40054	FlyBaseID:	FBgn0025807	Length:	456	Species:	Drosophila melanogaster
Sequence 2:	XP_012811318.1	Gene:	rad9b / 100490318	XenbaseID:	XB-GENE-990519	Length:	411	Species:	Xenopus tropicalis

Alignment Length:	442	Identity:	104/442 - (23%)
Similarity:	180/442 - (40%)	Gaps:	93/442 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKYTLEGSNARVIAKAVQSLSKVGKEMFIEIDQQSLQMRAINATQSAVGSISFKRSMFEVYDMPP 65
            ||..:.|.:.:|..|||.|||::|..::.:..::.|.:|.:|::.||...|.|....|..|....
Frog    26 MKCIIPGRHTKVFGKAVHSLSRIGNALWFDPLEKGLALRVVNSSMSAYACIVFSPHFFHSYHRSA 90

  Fly    66 -HS--------DFYCKISMKGCLAVFRNMN----EVEYCEL--NLLDNQTNLQVNLRCKLETTKE 115
             |.        :|.||.|:|..|.|||:::    .|:.|.:  |:.:...|.|:..|..:  ||.
Frog    91 LHEQGAAYAEINFKCKYSVKSVLPVFRSLSTLEKNVDKCTIYTNVNEGYMNFQLFYRNGI--TKT 153

  Fly   116 ATISIIDDQNINTNINTDQMPNIIRGDHKLLTDISNNFNSSEEELTLEANSGSVVAKNYIEGARV 180
            ..::..:.:.:......:..||::|...::|:|:..:|.|.:||:||......|..|.|.|....
Frog   154 HQLAYEECEPLQAVFAKNTCPNVLRIQPRVLSDVVVHFPSCQEEITLSVTPLRVSFKTYCEEELE 218

  Fly   181 NDKFMRTQLKLKPSEFEQYQVTKETVITFCIKEFRAFLLFAECLNASLTLEFDEAGMPFLLKIKK 245
            ..|.:.|::.|.|.||..:||.::..:|||:||.|.||.|||..::.:::...:||.|....: :
Frog   219 FSKSVHTEMHLGPEEFHYFQVGEDAEVTFCLKELRGFLGFAETTSSYISVHLSKAGKPVAFSM-E 282

  Fly   246 HGEIECLLIMSTLSPDDISFSEDYCQKDLTVQDEDVRAAAAKRKSSVSKPNVTNKRKGSSSEPA- 309
            :...|..:|::||:..::.                        |||...|.:....|..:..|.
Frog   283 NMFFEADIILATLAESEMG------------------------KSSQKSPGIIAGSKLCTPNPGT 323

  Fly   310 ----AVQPKRRVEETQLESSLDNPLFQFRDSEAPSVQHPRILAEVDTVVLIEDEAEQEALMLAAA 370
                |:.....::..|:.|:        :...|...|              :|..|:
Frog   324 GVSNAISLSENIDSQQIIST--------KHGNAEDAQ--------------QDTVEE-------- 358

  Fly   371 DAALEASMAPAPEPPNSTEVCFINTDDSQQPKP--------AKSSSDEDETI 414
                    .|...|.|.....|.....||..:.        |.:|.||||.:
Frog   359 --------TPNHSPYNKFCTLFFGAVSSQTQENADRMFCSLATASEDEDEDL 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rad9	NP_001097639.2	PCNA	7..262	CDD:238322	77/269 (29%)
Rad9	NP_001097639.2	Rad9	13..258	CDD:282052	73/259 (28%)
rad9b	XP_012811318.1	Rad9	38..295	CDD:367836	73/259 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I5020
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	140	1.000	Inparanoid score	I4389
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1176140at2759
OrthoFinder	1	1.000	-	-		FOG0002689
OrthoInspector	1	1.000	-	-		otm49138
Panther	1	1.100	-	-	LDO	PTHR15237
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3445
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	7.160