DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dysb and DBNDD2

DIOPT Version :9

Sequence 1:NP_001262023.1 Gene:Dysb / 40052 FlyBaseID:FBgn0036819 Length:288 Species:Drosophila melanogaster
Sequence 2:NP_060948.3 Gene:DBNDD2 / 55861 HGNCID:15881 Length:259 Species:Homo sapiens


Alignment Length:79 Identity:20/79 - (25%)
Similarity:32/79 - (40%) Gaps:19/79 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 QASGITTPISPLGL----------NESLSSSRSSSLSLSAPFQLTDGVPSHLNVAAGCSLLAKYE 94
            |:||:...:..|.|          ..|.|||..||.:|.:|....||..:.         ||:.:
Human   188 QSSGMDNHLEELSLPVPTSDRTTSRTSSSSSSDSSTNLHSPNPSDDGADTP---------LAQSD 243

  Fly    95 DDWQQIHGANEKNA 108
            ::.::..|..|..|
Human   244 EEEERGDGGAEPGA 257

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DysbNP_001262023.1 TMPIT 94..>189 CDD:285135 3/15 (20%)
DBNDD2NP_060948.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 27..56
Dysbindin 110..255 CDD:282316 18/75 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 174..259 20/79 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165148292
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_2BWXP
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D370127at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
43.800

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