Protein Alignment CG6865 and PRSS2

DIOPT Version :10

• Sequence 1: NP_001246825.1
• Gene: CG6865 / 40050
• FlyBaseID: FBgn0036817
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_001290343.1
• Gene: PRSS2 / 5645
• HGNCID: 9483
• Length: 261
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 92/260 - (35%)
• Similarity: 132/260 - (50%)
• Gaps: 37/260 - (14%)

  Fly    34 KIVGGSEAERNEMPYMVSLMRRGGHFCGGTIISERWILTAGHCICNGLQQFMKPA-----QIQGV 93
            |||||...|.|.:||.||| ..|.|||||::|||:|:::||||..:.:...:...     :||..
Human    23 KIVGGYICEENSVPYQVSL-NSGYHFCGGSLISEQWVVSAGHCYKSAINSKLSGRGCEYHRIQVR 86

  Fly    94 VGLHSIREYLNGIGNGPDALRVDFKNIVPHPQYDCNDVKHDIALLELVQPIRFSSHIQ------- 151
            :|.|:| |.|.|     :...::...|:.||:|:...:.:||.|::|..|...:|.:.
Human    87 LGEHNI-EVLEG-----NEQFINAAKIIRHPKYNSRTLDNDILLIKLSSPAVINSRVSAISLPTA 145

  Fly   152 PSCVGSEEGHRSLEQEYGTVSGWGWTHENQAENDRSDVLRKATVKIWNNEACERSYRSLGKSNTI 216
            |...|:|          ..:||||.|..:.|  |..|.|:.....:.:...||.||.  ||   |
Human   146 PPAAGTE----------SLISGWGNTLSSGA--DYPDELQCLDAPVLSQAECEASYP--GK---I 193

  Fly   217 GETQLCAGYENGQIDSCWADSGGPLMSKEHHLVGVVSTGIGCARPGLPGIYTRVSKYVSWMQKVI 281
            .....|.|:..|..|||..|||||::| ...|.|:||.|.|||:...||:||:|..||.|::..|
Human   194 TNNMFCVGFLEGGKDSCQGDSGGPVVS-NGELQGIVSWGYGCAQKNRPGVYTKVYNYVDWIKDTI 257

  Fly   282  281
            Human   258  257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6865	NP_001246825.1	Tryp_SPc	34..276	CDD:214473	90/253 (36%)
PRSS2	NP_001290343.1	Tryp_SPc	24..256	CDD:238113	90/256 (35%)