Protein Alignment CG6865 and PRSS48

DIOPT Version :10

• Sequence 1: NP_001246825.1
• Gene: CG6865 / 40050
• FlyBaseID: FBgn0036817
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_001340540.1
• Gene: PRSS48 / 345062
• HGNCID: 24635
• Length: 346
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 94/274 - (34%)
• Similarity: 131/274 - (47%)
• Gaps: 36/274 - (13%)

  Fly    21 IAFSNQPCSVRNPKIVGGSEAERNEMPYMVSLMRRGGHFCGGTIISERWILTAGHCICNGLQQFM 85
            |:...||  |.:.::|||.:|.....|:.|||.......|||:::|||.||||.||
Human    16 ISVCGQP--VYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHC--------- 69

  Fly    86 KPAQIQGVVGLHSIREYLNGIGNGPDALRVDF--KNIVPHPQYDCNDVKHDIALLELVQPIRFSS 148
                ||......|...:|..|..|....||.:  ..||.||:|  .|...|:|||:|...:.|:|
Human    70 ----IQPTWTTFSYTVWLGSITVGDSRKRVKYYVSKIVIHPKY--QDTTADVALLKLSSQVTFTS 128

  Fly   149 HIQPSCVGSEEGHRSLEQEYGTVSGWGWTHENQAENDRSDVLRKATVKIWNNEACERSYRSLG-- 211
            .|.|.|:.|.....:: ..:..|:|||...|: ::.|....|::|.|.|.:.:|||:.|..:|
Human   129 AILPICLPSVTKQLAI-PPFCWVTGWGKVKES-SDRDYHSALQEAEVPIIDRQACEQLYNPIGIF 191

  Fly   212 ---KSNTIGETQLCAGYENGQIDSCWADSGGPLMSKEHHL------VGVVSTGIGCARPGLPGIY 267
               ....|.|.::|||......|||..||||||..   |:      .||||.|:.|.: .|||:|
Human   192 LPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSC---HIDGVWIQTGVVSWGLECGK-SLPGVY 252

  Fly   268 TRVSKYVSWMQKVI 281
            |.|..|..|:...|
Human   253 TNVIYYQKWINATI 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6865	NP_001246825.1	Tryp_SPc	34..276	CDD:214473	88/254 (35%)
PRSS48	NP_001340540.1	Tryp_SPc	28..265	CDD:238113	89/257 (35%)