Protein Alignment CG6865 and Plat

DIOPT Version :10

• Sequence 1: NP_001246825.1
• Gene: CG6865 / 40050
• FlyBaseID: FBgn0036817
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_032898.2
• Gene: Plat / 18791
• MGIID: 97610
• Length: 559
• Species: Mus musculus
• Alignment Length: 280
• Identity: 81/280 - (28%)
• Similarity: 139/280 - (49%)
• Gaps: 48/280 - (17%)

  Fly    27 PCSV------RNP--KIVGGSEAERNEMPYMVSLMRR-----GGHF-CGGTIISERWILTAGHCI 77
            |||.      :.|  :|.||...:....|:..::..:     |..| |||.:||..|:|:|.||.
Mouse   293 PCSTCGLRQYKRPQFRIKGGLYTDITSHPWQAAIFVKNKRSPGERFLCGGVLISSCWVLSAAHCF 357

  Fly    78 CNGLQQFMKPAQIQGVVGLHSIREYLNGIGNGPDALRVDFKNIVPHPQYDCNDVKHDIALLEL-- 140
               |::| .|..::.|:|    |.|  .:..|.:....:.:..:.|.::|.:...:|||||:|
Mouse   358 ---LERF-PPNHLKVVLG----RTY--RVVPGEEEQTFEIEKYIVHEEFDDDTYDNDIALLQLRS 412

  Fly   141 --VQPIRFSSHIQPSCVGSEEGHRSLEQEYGT---VSGWGWTHENQAENDRSDVLRKATVKIWNN 200
              .|..:.||.:..:|:...    :|:....|   :||:| .|| .:....||.|::|.|:::.:
Mouse   413 QSKQCAQESSSVGTACLPDP----NLQLPDWTECELSGYG-KHE-ASSPFFSDRLKEAHVRLYPS 471

  Fly   201 EACERSYRSLGKSNTIGETQLCAGYE----NGQI-DSCWADSGGPL---MSKEHHLVGVVSTGIG 257
            ..|...:..   :.|:....||||..    |..: |:|..||||||   ::|:..|.|::|.|:|
Mouse   472 SRCTSQHLF---NKTVTNNMLCAGDTRSGGNQDLHDACQGDSGGPLVCMINKQMTLTGIISWGLG 533

  Fly   258 CARPGLPGIYTRVSKYVSWM 277
            |.:..:||:||:|:.|:.|:
Mouse   534 CGQKDVPGVYTKVTNYLDWI 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6865	NP_001246825.1	Tryp_SPc	34..276	CDD:214473	76/262 (29%)
Plat	NP_032898.2	FN1	38..80	CDD:214494
		Important for binding to annexin A2. /evidence=ECO:0000250	39..49
		EGF	83..115	CDD:394967
		Kringle	124..205	CDD:395005
		KR	210..295	CDD:238056	1/1 (100%)
		Tryp_SPc	311..556	CDD:238113	76/262 (29%)