Protein Alignment Indy and slc13a3

DIOPT Version :10

• Sequence 1: NP_730363.2
• Gene: Indy / 40049
• FlyBaseID: FBgn0036816
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: XP_031749933.1
• Gene: slc13a3 / 548493
• XenbaseID: XB-GENE-5765054
• Length: 602
• Species: Xenopus tropicalis
• Alignment Length: 592
• Identity: 193/592 - (32%)
• Similarity: 324/592 - (54%)
• Gaps: 64/592 - (10%)

  Fly    42 KGLVVFLVPLLCLPVMLLNEGAEFRCMYLLLVMAIFWVTEALPLYVTSMIPIVAFPIMGIMSSDQ 106
            |.:::...||:.|||:......|.:|::::|:||.:|.||||||.||:::|||.||::||:.|.:
 Frog    16 KYVILIATPLILLPVLFSLPPKEGKCLFVVLLMAFYWCTEALPLAVTALLPIVLFPLLGILPSSK 80

  Fly   107 TCRLYFKDTLVMFMGGIMVALAVEYCNLHKRLALRVIQIVGCSPRRLHFGLIMVTMFLSMWISNA 171
            .|..||.||..:|:.|:::|.|:|..|||:|:||:|:.:||..|.||..|::|.|.|||||:||.
 Frog    81 VCPQYFLDTNFLFLSGLLMAAAIEEWNLHRRIALKVLTLVGVQPARLILGMMMTTAFLSMWLSNT 145

  Fly   172 ACTAMMCPIIQAVLEELQAQGVCK---INHE----------------PQYQIVGGNKKNN----- 212
            |.||||.||..|:|:.|..:...|   :|:.                .:.|::..|::|.
 Frog   146 ASTAMMLPIANAILKSLYGERSSKEKGLNNNCDSTASIQEKGLHPVPTEMQLLAANEENKDLPEK 210

  Fly   213 -----------EDEPPYPTKITLCYYLGIAYASSLGGCGTIIGTATNLTFKGIYEARFKNSTEQM 266
                       :.|..|..:|...:.:.|.|::|:||..|:.|||.||...|..::.|. ..:.:
 Frog   211 IDIPTDTHPDLQKEKEYQNRIWKAFLISIPYSASIGGTATLTGTAPNLILLGQLKSFFP-GCDVV 274

  Fly   267 DFPTFMFYSVPSMLVYTLLTFVFLQWHFMGLW----------RPKSKEAQEVQRGREGADVAKKV 321
            :|.::..::.|.|::     |:|:.|    ||          |.|.|:..:::  .|....||.:
 Frog   275 NFGSWFAFAFPLMIL-----FLFVGW----LWISVLHGAISLRCKRKKKSDIR--SEAESKAKDI 328

  Fly   322 IDQRYKDLGPMSIHEIQVMILFIFMVVMYFTRKPGIFLGWADLLNSKDIRNSMPTIFVVVMCFML 386
            |.:.|:.|||.:..|..|.:.|....::.|||.|....|||.........:::..|.:.::.|..
 Frog   329 IQEDYRKLGPTNFAEKSVFVFFCLFAILLFTRDPKFIPGWASAFTPGFTSDAVTGISICIVLFFF 393

  Fly   387 PANYAFLRYCTRRGGPVPTGPTPSLITWKFIQTKVPWGLVFLLGGGFALAEGSKQSGMAKLIGNA 451
            |:....|::....  ..|.....:|::||..|:.|||.::.|||||||:|:|.:.||::..||:.
 Frog   394 PSEKPSLKWWFDL--KAPNTENKALLSWKKAQSTVPWNIILLLGGGFAMAKGCEVSGLSTWIGSR 456

  Fly   452 LIGLK-VLPNSVLLLVVILVAVFLTAFSSNVAIANIIIPVLAEMSLAIEIHPLYLILPAGLACSM 515
            |..|: :.|...:|||.:|:|.| |.|:||.|...:.:|:|:|:::.::::||||::|..:.||.
 Frog   457 LQPLEGISPALAVLLVTVLIASF-TEFASNTATIIVFLPILSELAIRLKVNPLYLMVPGTVGCSY 520

  Fly   516 AFHLPVSTPPNALVAGYANIRTKDMAIAGIGPTIITIITLFVFCQTWGLVVYPNLNSFPEW--AQ 578
            ||.||||||||::.....::..||||..|:...::.::.|.:...||...:: .|.:.|:|  :.
 Frog   521 AFMLPVSTPPNSIAFSTGHLMVKDMAKTGLVMNLMGVLLLSLAMNTWATSIF-QLGTIPDWVPSH 584

  Fly   579 IYAAAAL 585
            ||....|
 Frog   585 IYNVTEL 591

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Indy	NP_730363.2	CitT	120..545	CDD:440239	149/470 (32%)
slc13a3	XP_031749933.1	ArsB_NhaD_permease	<3..298	CDD:473875	98/291 (34%)
		CitT	94..567	CDD:440239	151/487 (31%)