Protein Alignment Indy and slc13a2

DIOPT Version :10

• Sequence 1: NP_730363.2
• Gene: Indy / 40049
• FlyBaseID: FBgn0036816
• Length: 590
• Species: Drosophila melanogaster
• Sequence 2: NP_998617.2
• Gene: slc13a2 / 406537
• ZFINID: ZDB-GENE-040426-2389
• Length: 613
• Species: Danio rerio
• Alignment Length: 594
• Identity: 218/594 - (36%)
• Similarity: 340/594 - (57%)
• Gaps: 63/594 - (10%)

  Fly    40 HWKGLVVFLVPLLCLPVMLLNEGAEFRCMYLLLVMAIFWVTEALPLYVTSMIPIVAFPIMGIMSS 104
            |...:::..||||.||:.|:....|.||.:.:::||:||.||.:||.:|:::|:|.||:||||.|
Zfish    16 HRNYILILCVPLLILPLPLVLPTPEARCGFAIILMALFWCTECMPLAITALLPVVLFPMMGIMES 80

  Fly   105 DQTCRLYFKDTLVMFMGGIMVALAVEYCNLHKRLALRVIQIVGCSPRRLHFGLIMVTMFLSMWIS 169
            .:.|..|.|||.::|:||::||:|||:.|||||:||.|:.:||..|..|..|.::||.|||||||
Zfish    81 GKVCVQYLKDTNMLFIGGLLVAIAVEHWNLHKRIALSVLLVVGVRPALLMLGFMIVTAFLSMWIS 145

  Fly   170 NAACTAMMCPIIQAVLEEL------------------QAQGVCKIN-HEPQYQIVGGNKKNNED- 214
            |.|.||||.||.|||||:|                  ||..:.::| .:|.....|....||.|
Zfish   146 NTATTAMMLPISQAVLEQLSATEADSDEKELREGQVNQAFELTEVNIKQPLDNTQGEKPNNNADV 210

  Fly   215 ---------------EPPYPTKITLCYYLGIAYASSLGGCGTIIGTATNLTFKGIYEARFKNSTE 264
                           |..| .::.....|.:.|::|:||..|:.||..||..||..:..|.::.:
Zfish   211 EEGINALSERRRKAREAKY-LRLFKGMSLSVCYSASIGGTATLTGTTPNLILKGQMDEIFPDNND 274

  Fly   265 QMDFPTFMFYSVPSMLVYTLLTFVFLQWHFMGLWRPKSKEAQEVQRGREGADVAKKVIDQRYKDL 329
            .::|.::..::.|:|::..:|::::||..::|.   ..|::.......||...|.||:...||.|
Zfish   275 VINFASWFGFAFPNMVLMLVLSWLWLQCMYLGF---NFKQSFGCGTKNEGDKDAYKVMKNEYKKL 336

  Fly   330 GPMSIHEIQVMILFIFMVVMYFTRKPGIFLGWADLL---NSKDIRNSMPTIFVVVMCFMLPANYA 391
            ||||..|..|:::|||:|:::|||:||...|||..|   |.:.:.:....||:..:.|::|:...
Zfish   337 GPMSFAEGAVLVIFIFLVILWFTREPGFMPGWATELFNKNGQYVTDGTVAIFMSTLFFVIPSRVD 401

  Fly   392 FLRYCT--------RRGGPVPTG----------PTPSLITWKFIQTKVPWGLVFLLGGGFALAEG 438
            ||  |:        ...|....|          .||:|:.||.:..::||.:|.|||||||||.|
Zfish   402 FL--CSIKYEEQDEEAVGEEQDGVEKEKKRKLKGTPTLLNWKVVHERMPWNIVLLLGGGFALASG 464

  Fly   439 SKQSGMAKLIGNALIGLKVLPNSVLLLVVILVAVFLTAFSSNVAIANIIIPVLAEMSLAIEIHPL 503
            |::||::..:|.:|..||.:|...:.:::.|:....|..|||.|...:.:|:||.|:..|.:|||
Zfish   465 SEESGLSVWLGQSLSPLKSIPPFAISIILCLLVGTFTECSSNTATTTLFLPILASMATTIGLHPL 529

  Fly   504 YLILPAGLACSMAFHLPVSTPPNALVAGYANIRTKDMAIAGIGPTIITIITLFVFCQTWGLVVYP 568
            |::||..::.|:||.|||:|||||:...|.|::..|||.||....||.|:.:.:...|||:.::
Zfish   530 YVMLPCTISASLAFMLPVATPPNAIAFSYGNLKVLDMAKAGFILNIIGILCINLGINTWGMAMF- 593

  Fly   569 NLNSFPEWA 577
            .|::||.||
Zfish   594 KLDTFPSWA 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Indy	NP_730363.2	CitT	120..545	CDD:440239	171/480 (36%)
slc13a2	NP_998617.2	ArsB_NhaD_permease	40..595	CDD:473875	205/561 (37%)